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《Infectious Disease Information》 2012-06
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Epidemiological investigation on HIV/AIDS patients in Guangdong Province in 2011

ZHANG Jian-sheng, NIE Jing-min, HE Hao-lan, CAI Wei-ping* Department of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou, Guangdong 510060, China  
Objective To investigate the epidemiological characteristics of emerging HIV/AIDS patients in Guangdong Province in 2011. Methods Totally 835 HIV/AIDS patients with antibody positive and without receiving highly active antiretroviral therapy, who were treated in Guangzhou Eighth People's Hospital in 2011, were included in the study. Gender, age, routes of infection and other general data were recorded. CD4+ and CD8+ T lymphocyte counts, WBC, HGB, PLT, ALT, AST, TBIL, HBV markers and HCV antibody were detected. SPSS 13.0 software was used to describe and analyze the statistics. Results The mean age of the 835 HIV/AIDS patients was 39.7±11.8 years old. The infection rate in males (n=585, 70.1%) was higher than that in females (n=250, 29.9%). The infection routes were mainly sexual transmission (n=689, 82.5%), 557 patients (66.7%) through heterosexual transmission and 132 (15.8%) through homosexual transmission, intravenous drug abuse (n=126, 15.1%) and blood transfusion (n=20, 2.4%). Of the 725 HIV/AIDS patients with complete data, 514 (70.9%) were affected with HIV infection alone (group A), 103 (14.2%) with HIV/HBV coinfection (group B), 83 (11.4%) with HIV/HCV/HBV coinfection (group C), and 25 (3.4%) with HIV/HCV coinfection (group D). The four groups had significant differences in the infection routes (χ2=415.358, P=0.000), group A and B mainly through heterosexual transmission, and group C and D mainly through intravenous drug use. The level of PLT dropped in 65 patients (7.8%), and that of group B dropped more greatly than that of group A, and the difference between the two groups was significant (χ2=10.451, P=0.001). The coinfection might aggravate liver injury. AST level in coinfection groups (group B, C and D) increased more significantly when compared with single infection group (group A) (χ2AB=20.012, PAB=0.000; χ2AC=14.237, PAC=0.000; χ2AD=26.725, PAD=0.000). ALT level in group D was significantly higher than that in group A (χ2=8.395, P=0.004). TBIL level in group B was significantly higher than that in group A (χ2=9.130, P=0.003). Conclusions The emerging HIV/AIDS patients in Guangdong Province in 2011 are mainly young male adults, and the majority are infected through sexual transmission. The rate of HIV and HBV/HCV coinfection is higher, and the HIV patients coinfected with HCV are mainly infected through injection drug use. The coinfection is the important cause leading to the aggravation of liver injury and myelosuppression.
【Fund】: 国家“十二五”科技重大专项(2012ZX10001003-003)
【CateGory Index】: R512.91
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【References】
Chinese Journal Full-text Database 2 Hits
1 LIANG Bi-yan;WANG Jian;ZHANG Xiao-ping;XU Li-ran;DENG Xin;LI Xiu-hui;FANG Lu;TAN Xing-hua;MAO Yu-xiang;ZHANG Guo-liang;TCM Center for AIDS Prevention and Treatment,China Academy of Chinese Medical Sciences;;Logistic regression analysis of risk factors influencing death in HIV/AIDS patients[J];Infectious Disease Information;2013-04
2 YAN Yi;JIANG Shi-qiang;WEN Qun-wen;Nanshan Center for Disease Prevention and Control;;HIV/AIDS epidemic in Nanshan District in Shenzhen from 1998 to 2012[J];Infectious Disease Information;2013-04
【Citations】
Chinese Journal Full-text Database 8 Hits
1 WANG Yong-yi,LI Jun,CHEN Wen,WANG Shu,ZHANG Ling-xia Editorial Office,Infectious Disease Information,Beijing 100039,China;New global situation of prevention and control of AIDS and other infectious diseases[J];Infectious Disease Information;2010-06
2 YIN Ning, MEI Shan, ZHANG Linqi, et al National Center for AIDS Prevention and Control, Beijing 100050, China;Outbreak of HIV and HCV co-infection among intravenous drug users and illegal blood donors in China[J];Chinese Journal of Infection and Chemotherapy;2002-02
3 MA Jian-xin WANG Jiang-rong SHEN Yin-zhong ZHANG Ren-fang LIU Xi-nian JIANG Xue-yan SUN Hong-qing LU Hong-zhou (Shanghai Public Health Center Affiliated to Fudan University,Shanghai 201508,China);Clinical epidemiology studies on HIV-1/AIDS subjects co-infected with HBV and/or HCV in Shanghai[J];Journal of Microbes and Infection;2006-04
4 CAI Yu-mao,LIU Hui,PAN Peng,et al.(Shenzhen Center for Chronic Disease Control and Prevention,Shenzhen 518020,China);Investigation of STD/AIDS high risk behavior among male sex workers in Shenzhen[J];Chinese Journal of AIDS & STD;2008-02
5 ZHOU Ning LIU Zhong-quan BAI Jian-yun.(Tianjin Municipal Center for Disease Prevention and Control,Tianjin 300011,China);A survey of level of AIDS related knowledge and high risk behavior among young men who have sex with men under 40 years in Tianjin in 2006[J];Chinese Journal of AIDS & STD;2008-05
6 WANG Li1,BAI Li2,YANG Hui-qing1,CEN Wen1,YANG Jing1,LIU Yong1,CHANG Hui-ling1,PENG Zhi-peng1(1.Department of Dermatology,Shanxi Medical University No.2 Hospital,Taiyuan 030001,China;2.Department of Dermatology,Shanxi Medical University No.1 Hospital,Taiyuan 030001,China);The Significance of Screening HIV of Venereal Outpatients[J];The Chinese Journal of Dermatovenereology;2010-01
7 ZHANG Chuntao,WEI Daying,LI Xiuhua,et al.Division of Cytology National Institute for the Control of Pharmaceutical and Biological Products(Beijing 100050,China);Investigation on infection status of HIV and HCV in drug user in Liangshan area[J];China Public Health;2005-11
8 LIU Zhen,XING Wen-ge,ZHANG Yong-hong,ZHANG Qi,LONG Xiao-shan,ZHANG Gui-yun,WU Hao,JIANG Yan Chinese Center for Disease Control and Prevention,Beijing 100050,China;Study on the epidemiology and HCV genotype distribution of HTV/HCV co-infection among HIV infected blood donors in China[J];Chinese Journal of Hepatology;2006-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Yu Fujun, He Shengsong, Zhang Shuling, et al.Department of Infection, the First Affiliated Hospitalof Wenzhou Medical College. Wenzhou, Zhejiang 325000;Discussion of effect of lamivudine treatment on IL-2 and IL-4 in chronic hepatits B[J];;2006-01
2 QIN Xin-Tian1,2, LU Yue1,2, CHEN Xiao-Qin1,2, XU Hai-Peng1,2, FAN Hui-Jie1,2 1. State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China 2. Department of Medical Oncology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, P. R. China;Correlation of Hepatitis B Virus Infection to Non-Hodgkin's Lymphoma[J];Chinese Journal of Cancer;2007-03
3 ZHAO Jing1, PAN Pinliang1, WANG Zhe2, et al. 1National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, China CDC, Beijing 10000, China; 2. Henan Center for Disease Control and Prevention;Study on HIV/HCV co-infection and genotyping of HCV in three provinces of China[J];Chinese Journal of Blood Transfusion;2009-05
4 ZENG Dong feng,LIU Lin,KONG Pei yan *, et al. (Department of Hemotology, Xinqiao Hospital,the Third Military Medical University,Chongqing 400037,China);Clinical study on the hepatic impairment associated with hematopoietic stem cell transplantation[J];Chongqing Medical Journal;2003-10
5 PENG Yong,YU Hua,WANG Xian Yili Center for Disease Prevention and Control,Xinjiang,Yili Prefecture 835000,China;Analysis of tuberculosis patients in Yili Prefecture,Xinjiang Uyghur Autonomous Region using network reporting system[J];Infectious Disease Information;2012-01
6 CHENG Juan,DUAN Hong-yan,LI An-xin Dermatology and STD Center,Out-Patient Clinic,302 Hospital of PLA,Beijing 100039,China;Current state of epidemiology,diagnosis and treatment of syphilis[J];Infectious Disease Information;2012-01
7 XI Cheng-hui,YIN Zheng-liu,DUAN Yi-juan,FANG Ke-fen,YANG Ying-bo,YANG Guang-wen,QIU Gui-xiang,LI Zhong-cheng,YANG Lu(Ruili Municipal Center for Disease Control and Prevention of Yunnan Province,Ruili,Yunnan 678600,China);Study on Combined Infection with HIV/HCV in 258 Drug Addicts and Influential Factors[J];Endemic Diseases Bulletin;2010-01
8 Wang Xue-mei Gong Xiang-feng Wang Li-mei,et al Cangzhou Detention Hospital of Hebei Province,Cangzhou 061001,China;Analysis of The Relevant Factors of The Discriminated Mentality of Patients with Chronic Hepatitis B and The Intervention of Personalized Nursing[J];Chinese Journal of Medicinal Guide;2009-03
9 Wang Xue-mei,Gong Xiang-feng,Wang Li-Mei,et al. (Cangzhou Contagious Hospital of Hebei Province,Cangzhou 061000,China);Analysis of Mental State of Patients with Chronic Hepatitis B and Their Mental Intervention[J];Chinese Journal of Medicinal Guide;2010-01
10 TIAN Kun-lun,WANG Jing,WANG Yi-xin et al(Department of Basic Medicine,Dali University,Dali,Yunnan 671000,China);Analysis on the Infection Rates of Blood Transmission Virus in Intravenous Drug Users[J];Journal of Dali College;2005-05
China Proceedings of conference Full-text Database 1 Hits
1 WU Guo-hui CHEN Hong MENG Xiong ZHOU Chao (Chongqing Center for Disease Control and Prevention,Chongqing 400042,China);EPIDEMIOLOGICAL SURVEY ON THE HCV AND HIV INFECTION AMONG DRUG USERS IN CHONGQING CITY[A];[C];2009
【Co-references】
Chinese Journal Full-text Database 9 Hits
1 XIE Shi-ping1,CHEN Jian-she2,LIU Ai-hua2,LI Su-xiang1,PENG Bo1,ZHU Ying-jun1,CHEN Xiao-hui1,HOU Ming-jie1(1AIDS Institute of Henan University of TCM,Zhengzhou 450008,China;2Andropathy Department of Henan Provincial Hospital of TCM,Zhengzhou 450002,China);Logistic analysis on quantitive diagnosis of deficient syndromes of HIV/AIDS[J];China Journal of Traditional Chinese Medicine and Pharmacy;2010-10
2 Zhao Qingxia,Sun Yan,He Yun,et al. Infectious Diseases Hospital of Henan Province,Zhengzhou 450015,China;Epidemiological and clinical characteristics of AIDS in Henan province[J];Infectious Disease Information;2009-06
3 LUO Hong-bing,LU Ran,MEI Jing-yuan,LU Ji-yun,SONG Li-jun,FU Li-ru,JIA Man-hong* AIDS Prevention and Control Center,Yunnan Provincial Centers for Disease Control and Prevention,Kunming,Yunnan 650022,China;HIV risk factors among 188 young students with HIV infection or AIDS in Yunnan province[J];Infectious Disease Information;2011-06
4 YAO Qin-jiang,LIANG Xin,MA Wei-guo,WEI Liang-hong,LI Can,HUANG Zi-qun,HUANG Li-jing,WANG Guang-yin(Department of Infectious Diseases,First People's Hospital of Qinzhou,Qinzhou 535000,China);Prognostic Factors of Disseminated Penicilliosis Marneffei in Patients with Acquired Immunodeficiency Syndrome[J];Guangxi Medical Journal;2011-05
5 LI Xia, LEI Su-yun, LAO Yun-fei, CHEN Qing-ling, LI Hui-qin* Yunnan AIDS Care Center, Yunnan Provincial Hospital of Infectious Diseases, Kunming, Yunnan 650301, China;AIDS clinical teaching practice[J];Infectious Disease Information;2012-06
6 DING Xian-bin,ZHANG Wei,FENG Lian-gui,LU Rong-rong,XU Jing,ZHOU Chao,OU Yang-lin(Chongqing Center for Disease Prevention and Control,Chongqing 400042,China);Study on AIDS epidemic and strategy of AIDS prevention and control in Chongqing[J];Journal of Tropical Medicine;2011-03
7 LI Jie,CHEN Xi,QIN Bi-yun,et al.(School of Public Health,University of South China,Hengyang 421002,Hunan,China);Investigation of HIV-related Risk Factors Among Elderly HIV-positive Patients[J];Practical Preventive Medicine;2010-02
8 WEN Jian-hua,ZHANG Hong,WU Li-ping,ZHU Lin,CHEN Wu,LU Jie-ying(Tianhe District Center for Disease Control and Prevention of Guangzhou City,Guangdong,Guangzhou 510655,China);Characteristics of HIV /AIDS epidemic in Tianhe district of Guangzhou city,1995-2010[J];Journal of Tropical Medicine;2012-09
9 DING Hai-bo,LIU Jing,XU Jun-jie,et al.(From Key Laboratory of AIDS Immunology of Ministry of Health,No 1 Hospital of China Medical University,Shenyang 110001,China);Analysis on quality of life and related factors among people living with HIV/AIDS[J];Chinese Journal of AIDS & STD;2012-01
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 LU Ji-yun 302 Hospital of PLA,Beijing 100039,China;Situation analysis and prospect of major infectious diseases in China in 2010[J];Infectious Disease Information;2010-01
2 ZHANG Ling-xia,WANG Yong-yi,CHEN Wen,LI Jun,WANG Shu Expert Panel,302 Hospital of PLA,Beijing 100039,China;Focus on 2009 global epidemic situation of infectious diseases[J];Infectious Disease Information;2010-01
3 HE Qun 1, WANG Ye 1, LIN Peng 1, ZHANG Zhou-bin 2, ZHAO Xi-xi 1, XU Hui-fang 2. 1.HIV/AIDS Institute, Guangdong Center for Disease Control and Prevention, Guangzhou 510300, China; 2.HIV/AIDS Division, Guangzhou Center for Disease Control and Prevention, Guangzhou 510300, China;KAP study on AIDS among men who have sex with men in Guangzhou, Guangdong province[J];Chinese Journal of Disease Control and Prevention;2005-02
4 Qi Shuzhen,Zhang Guocheng,Cao Ningxiao,et al.Institute of Dermatology,Chinese Academy of Medical Sciences & Peking Union Medical College,Nanjing,210042;Serological screening of HIV/STDs and assessment of risk factors in male sex workers[J];China Journal of Leprosy and Skin Diseases;2005-12
5 Li Qunhui,Wu Hao,Sun Lijun,Huang Xiaojie,Liu Yi,Sun Xin,Liu Rusheng,Liu An,Wei Hongjuan,Ye Jiangzhu (Beijing Center for AIDS and STDs Clinical Diagnosis and Therapy,Beijing Youan Hospital,Capital University of Medical Sciences);Infections of STDs/HIV and Assessment of Risk Factors in Male Sex Workers[J];Journal of Capital University of Medical Sciences;2006-06
6 Qu Shuquan,Zhang Dapeng,Wu Yuhua,et al National Centers for AIDS/STD Control and Prevention,China CDC,Beijing 100050,P R China;A Survey of Knowledge,Attitude and Practice Related to HIV/AIDS among Men Who Have Sex with Men in a Northeast City of China.[J];Journal for China AIDS/STD;2002-06
7 LU Zhuo-ping,ZHU Zuo-jin.(School of Public Health,Guangxi Medical University,Nanning,Guangxi 530021,China);The study of knowledge and attitude for AIDS among the mobile population[J];Journal for China AIDS/STD;2004-02
8 ZHANG Bei-chuan,WU Shao-wen,LI Xiu-fang,et al.(The Affiliated Hepital of Medical College,Qingdao University,Qingdao,Shandong 266003,China);Study on high risk behaviors among male sex workers related to STI/HIV.[J];Journal for China AIDS/STD;2004-05
9 WU Shao-wen,ZHANG Bei-chuan,LI Xiu-fang.(The Affiliated Hospital of Medical College,Qingdao University,Qingdao,Shandong 266033,China);AIDS high risk behavioral surveillance and comparison of homosexual/bisexual men in China.[J];Journal for China AIDS/STD;2004-05
10 ZHANG Man,RUI Bao-ling,CHEN Yang-gui.(Urumqi Sanitary and Anti-epidemic Station Xinjiang 830002,China);Investigation of the prevalence of HIV.HBV.anti-HCV infection and syphilis among drug users in Urumqi.[J];Journal for China AIDS/STD;2004-05
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