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《Infectious Disease Information》 2018-04
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Comparison the therapeutic efficacy of loopelectrosurgical excision procedure on cervical intraepithelialneoplasia (grade Ⅰ) combined with high-risk HPV infection with focused ultrasound

LIN Lin;FU Ya-jun;Department of Gynaecology and Obstetrics, the First People's Hospital of Chongqing Liangjiang New Area;  
Objective To investigate and compare the therapeutic effect of loop electrosurgical excision procedure on cervical intraepithelial neoplasia(grade Ⅰ) combined with high-risk HPV infection with focused ultrasound. Methods Sixty-seven CIN Ⅰ patients were selected from February 2015 to October 2017 in our hospital and they were divided into LEEP group and ultrasound group. LEEP group was treated with LEEP, and ultrasound group was treated with focused ultrasound. Therapeutic effect was observed. The levels of inflammatory factors before and after surgery were detected. Results The vaginal bleeding volume, bleeding time, drainage volume, drainage time and the time of cervical wound closure in the ultrasound group were(7.50±1.30) ml,(5.55±1.83) d,(9.89±1.90) ml,(6.51±1.15) d and(4.01±1.15) weeks, which were significantly shorter than those in the LEEP group(P 0.05); The effective rate of treatment in the ultrasound group and the LEEP group were 87.50% and 91.43%, respectively, and the difference was not statistically significant between 2 groups(P 0.05). The HPV negative rates in the ultrasound group and the LEEP group were 93.75% and 94.29%, respectively, and the difference was not statistically significant in 2 groups(P 0.05). Conclusions LEEP and focused ultrasound treatment are both effective in treatment of grade Ⅰ CIN combined with high-risk HPV infection. Moreover, focused ultrasound reduces vaginal discharge and bleeding and accelerates cervical wound healing.
【CateGory Index】: R737.33
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