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Correlation Between Risk Factors of Carotid Artery Stenosis and Ischemic Stroke

Zheng Yu,Hua Yang,Ling Chen,et al Dept Ultrasound,Xuanwu Hospital,Capital University of Medical Sciences,Beijing 100053 China  
Objective:To study the risk factors of carotid artery stenosis(CAS) and the relationship of the degree of stenosis and characteristics of plaques with ischemic stroke occurrence.Methods:CDFI was used to study the morphology,structure,and hemodynamics of bilateral carotid arteries in 1 603 initial examined patients,and to emphasize the degree of stenosis and echo characteristics of plaques.The data about the risk factors of atherosclerosis and ischemic stroke occurrence were recorded.The patients were divided into A(stenosis50%)and B(stenosis50%.or occlusion)groups.Results:Carotid stenosis was found in 277 patients(17 3%).Older age,male,hypertension,ischemic cardiac disease and diabetes mellitus were in close relation to carotid stenosis ( r =0 024?0 777?0 827?0 762?0 750 respectively).The stroke incidence in the group B was 37 5%(103/277)which was higher than that of group A,21 6%(287/1 326, P 0 001) In the group B,the stroke occurrence of CAS was between 51-69%,(30 4%,38/125),while that of CAS greater than 70% or occlusion was 42 8%(65/152) The total plague occurrence was 64 3% (1 032/1 603).The incidence ratio of irregular and heterogeneous plaques was higher in patients with stroke and TIA than those without.Conclusions:Older age,male,hypertension,ischemic cardiac disease and diabetes mellitus are all risk factors of CAS.The stroke occurrence is higher along with the increment of stenosis degree.Irregular and heterogeneous plaques also have relationship with stroke.
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