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《Chinese Journal of CT and MRI》 2011-01
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The study of correlation of CT features, pathology and serum CA50 concentration in peripheral lung cancer

TAN Li-lian, ZHOU Jie, LI Zhi-ming, et al. CT Division, the Second Affiliated Hospital of Guangzhou Medical College, Guangzhou, 510260  
Objective To discuss the correlation of pathology, CT features and serum CA50 concentration of peripheral lung cancer. Methods The CT, pathology and CA50 of 48 cases of peripheral lung cancer, confirmed by operation and pathology, were analyed. Results The serum CA50 concentration was 5.90?.69ng/ml(adenocarcinoma), 3.44?.63ng/ml (squamous carcinoma). There was no significant difference between the serum CA50 concentration of adenocarcinoma and squamous carcinoma. There was no correlation between the serum CA50 concentration and the tumor differentiation degree in lung cancer.(r= -0.117). There was no significant difference between lung cancer with deep lobulation sign, diameter3cm, pleural indentation sign, spiculation sign, spinous protuberant sign, increased CT value 20Hu, cavity, calcification or lymph node enlargement of hilar or mediastinal and their serum CA50 concentration. There was no correlation between the percentage of Ki-67 antigen and the serum CA50 concentration in lung cancer(r=0.024). The serum CA50 concentration was 4.58?.82ng/ml( p53 positive group), 6.41?.43ng/ml (p53 negative group). Conclusion There was no significant difference between tumor differentiation degree , CT features, the expression of Ki-67 antigen or p53 and serum CA50 concentration in peripheral lung cancer.
【Fund】: 广州市属高校科技计划项目(61028);; 广东省医学科研基金项目(A2004298);; 广州医学院博士启动基金项目(0706073)
【CateGory Index】: R734.2
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