Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Agricultural University of Hebei》 2008-02
Add to Favorite Get Latest Update

Study on experimental mastitis induced by Staphylococcus aureus in mice

LIU Ping1,2,HAO Man-liang1,QIN Jianhua1,YE Bao-na1,HOU Xi-cheng3,WANG Wei-yu1,XIE Fei1(1.College of Animal Science and Technology,Agricultural University of Hebei,Baoding 071001,China;2.The First Middle School of Cangzhou,Cangzhou 061001,China;3.College of Forestry,Agricultural University of Hebei,Baoding 071001,China)  
To establish mice mastitis model,thirty-five lactating BALB/C female mice were random1y divided into seven groups.50 μL of sterile physiological saline solution(PSS) or different concentration of Staphylococcus aureus were injected into the fourth abdominal mammary gland via the teat duct at 8~10 d after parturition.The changes of temperature,histopathologic evaluations,interstitial width,alveoli cases thickness from each group and colony for units(CFU),Tumor necrosis factor-α(TNF-α)and interleukin-γ(IFN-γ) concentration in the mammary glands were examined.The results showed that the temperature of treatment groups decreased at the beginning,and then increased,particularly in T3 group.Histopathologic examination of mammary gland revealed that the number of polymorphonuclear neutrophils(PMN) and exfoliated epithelial cells were present in alveoli cases,with increased interval width,and inflammation of the mammary glands was significant.Along with the increase of dose,pathological changes of mammary glands became more serious.The interstitial width of T3 group was wider than those of other groups.In comparison with those of PSS-treated mice,alveoli cases thickness,CFU,TNF-α and IFN-γ concentration were significantly(P0.01)higher in 50 μL1.4×104 CFU/mL Staphylococcus aureus-infused mammary glands.The results demonstrated that the mice experimental mastitis model infused with Staphylococcus aureus via teat duct was the same as immunopathology and inflammatory response,and can be used as a pathological model.
【Fund】: 国家十一五重大专项子专题“华北农区奶牛疾病综合防治技术应用与示范”(2006BAD04A10-4)
【CateGory Index】: S858.23
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 LI Li1,2,WEI Chun-mei2,3,LIU Dai-cheng1 ,YANG Hong-jun2 ,HE Hong-bin2,WANG Chang-fa2,GAO Yun-dong2,ZHONG Ji-feng2,PENG Guang-neng3(1.College of Life Science,Shandong Normal University,Jinan 250014,China;2.Dairy Cow Research Center of Shandong Academy of Agricultural Sciences,Jinan 250100,China;3.College of Animal Medical Science,Sichuan Agricultural University,Yaan 625014,China);Inflammation Pathology of Mouse Mammary Gland in Lactation Period Attacked by Staphylococcus aureus[J];Shandong Agricultural Sciences;2011-02
Chinese Journal Full-text Database 2 Hits
1 LI Hong-sheng,YU Jie,LI Xin-pu,LUO Jin-yin,XU Ji-ying,GUO Fu-cun,ZHANG Li-hua (Lanzhou Institute of Animal and Veterinary Pharmaceutics Science, CAAS,Lanzhou,Gansu,730050,China);Inducing Acute Mastitis in Milk Goats by Using Three Common Pathogenic Bacteria Isolated from Dairy Mastitis[J];Progress In Veterinary Medicine;2004-04
2 LIU Di jie, SHI Wei, ZHUANG Wei dong, FENG Qi hui (FUNG Ki fai), CHEN Zhang liu (College of Veterinary Medicine, South China Agric. Univ., Guangzhou 510642, China);Study on Mastitis Model Infected Experimentally with Staphylococcus aureus in Lactating Milky Goats[J];Journal of South China Agricultural University;2002-04
Chinese Journal Full-text Database 9 Hits
1 LIU Di jie, SHI Wei, ZHUANG Wei dong, FENG Qi hui (FUNG Ki fai), CHEN Zhang liu (College of Veterinary Medicine, South China Agric. Univ., Guangzhou 510642, China);Study on Mastitis Model Infected Experimentally with Staphylococcus aureus in Lactating Milky Goats[J];Journal of South China Agricultural University;2002-04
2 WANG Jia xin 1, CHEN Yao xing 2,ZHAO Xiang ru 1, DENG Ze pei 2, CUI Ping 1, SUN Bing gui 2 (1.Laboratory of Reproductive Immunology, Zhangjiakou Agricultural College,Zhangjiakou 075131;2.Laboratory of Reproductive Immunology,China Agricultur;Mucosal Immunologic Properties of Mast Cells in Mammary Gland of Dairy Cow[J];Shanghai J.of Immunology;2001-03
3 ZHANG Da-song,ZHANG Yuan-shu,ZOU Si-xiang,CHEN Wei-hua(Key Laboratory Animal Physiology and Biochemistry,Ministry of Agriculture,Nanjing Agricultural University,Nanjing,Jiangsu 210095,China);Inducing mastitis in rats by jointly using two pathogens[J];Journal of Northwest A & F University(Natural Science Edition);2007-07
4 ZHANG Xin jun,LI Yu jun,ZHUANG Guo hong,JIAO Ku hua (College of Animal Husbandry and Veterinary Medicine,Yangzhou Univ,Yangzhou 225009,China);Isolation & identification of the pathogen of cow mastitis[J];ANIMAL HUSBANDRY & VETERINARY MEDICINE;2000-05
5 CHEN Shen-ren1, CHEN Lin-xin1, CHEN Shao-ru2 (1. The 2nd Clinical School in Medical College of Shantou University,Shantou 515041; 2. Pathophysiology of Medical College, Shantou University, Shantou 515031, China);Inducible nitric oxide synthase in diseases[J];Chinese Journal of Pathophysiology;2000-02
6 ZHANG Xiang,LIN Lu-biao,JI Xi-tuan,et al.Institute of Neurosurgery of Chinese PLA,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China;Expression of inducible nitric oxide synthase induced by hypoxia in neural stem cells from mouse[J];Chinese Journal of Experimental Surgery;2003-07
7 PENG Xian-feng,ZENG Zhen-ling,CHEN Zhang-liu (Laboratory of Veterinary Pharmacology, College of Veterinary Medicine,South China Agricultural University,Guangzhou 510642,China);Screening of Therapeutic Drug for Clinical Mastitis in Dairy Cattle and Their Efficacy[J];Chinese Journal of Veterinary Science;2003-02
8 LI Yan1, ZHANG Xue-jun2, WANG Meng-jun1 (1.Department of Hematology, Handan First Hospital, Handan, Hebei 056002, P.R.China; 2.Department of Hematology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, P.R.China);Study on interferon-γ and interleukin-4 levels in acute leukemia patients[J];China Journal of Modern Medicine;2006-21
9 Long-Gang Li, Hui-Mian Xu, Department of Surgical Oncology, First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning Province, China;Inducible nitric oxide synthase, nitrotyrosine and apoptosis in gastric adenocarcinomas and their correlation with a poor survival[J];世界胃肠病学杂志(英文版);2005-17
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 Wu Guojuan Zhang Zhongwen Liu Fenghua Sheng Hong Kong Gang (Beijing Agricultural Collage,Beijing 102206);Study on Positive Rate and Regularity of Milking Cow Mammitis of Milk Cow Dairy in Beijing Area[J];Journal of Beijing Agricultural College;2001-03
2 LI Hong-sheng, YU Jie, LI Xin-pu, LUO Jin-yin, XU Ji-ying, ZHANG Li-hua,PAN Hu, ZHANG Zhi-chang,YUAN Yong-long, YANG Yu-ying, LIU Chun-chuan, HOU Yi-zhao (Institute of Lanzhou Animal Science and Vet. Pharmaceutics,Chinese Academy of Agricultural Sciences,Lanzhou,Gansu,730050,China);Study on Relativity between Mastitis Type and Pathogenic Bacterial Infection in Dairy Cows[J];Progress In Veterinary Medicine;2004-06
3 Pu Shijin Bai Chaoyong He Hongmei Liu Hongwei (Dept. of Vet. Med., Anim. Sci. and Vet. Med. Coll., YangZhou Univ., YangZhou 225009);EXPERIMENTAL MASTITIS INDUCED BY ESCHERICHIA COLI ENDOTOXIN IN DAIRY GOATS[J];;1998-04
5 Gao Yulong, Bao Hongmei, Sun Yanming, Ouyang Wuqing(College of Animal Science and Veterinary Medicine, Northwestern Scienceand Technology University of Agricultrue and Forestry Yangling, Shaan xi 712100);The Research Progress of New Antibacterial Drugsfor Prevention and Treatment of Bovine Mastitis[J];CHINA DAIRY CATTLE;2000-03
6 Yuan Yunglong Zhang Lihua Liu Chunchuan Yang Yuying Hou Yizhao Li Hongsheng Pan Hu Zhang Zhichang Yu Jie Li Xinpu (Institute of Traditional Chinese Veterinary, Chinese Academy of Agricultural Sciences Lanzhou 730050 Zhang Yongxin (Institute of Gongbei Animal and Plant Quarantine Zhuhai 519020;A SURVEY OF THE PATHOGENS OF BOVINE MASTITIS IN CHINA[J];Scientia Agricultura Sinica;1992-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved