Effect of alanyl-glutamine dipeptide on glutathione concentration and antioxidation in burned rats
SHI Ying qin, ZHANG Wen jie, WANG Qing, ZHANG Xiao peng, ZHOU Jian li (Nutriology Center,Hebei Province Hospital,Shijiazhuang 050071,Hebei, China)
Objectives:In the study, effect of Ala Gln on glutathione concentration and antioxidation were investigated in burned rats . Methods:Thirty male SD rats were randomly divided into three groups,A:control group,B:TPN group,C:Ala Gln PN group.The nutrient solution was administered through central venous catheter for 7 days.Glutathione concentration and levels of xanthine oxidase(XOD) and superoxide dismutase(SOD) in the serum were determined. Results:Compared with control group and TPN group,the levels of serum glutathione and SOD in group C were significantly increased( P 0.05),and the level of XOD in group C was significantly decreased( P 0.05). Conclusions:Ala Gln can increase glutathione concentration and the antioxidative capacity in burned rats.
【CateGory Index】： R459.3