Study of examination of liver function following liver injury
MA Xiao lin,CHEN Wei,JIN Rong bing (Center for Treatment of Trauma and War Wounds,Daping Hospital,Third Military Medical University,Chongqing 400042, China)
Objective To explore the parameters used for the clinical evaluation of post traumatic hepatic function.?Methods By establishing the animal model of liver impact injuries,blood was sampled before injuries and 30min,1h,3h,6h,9h after injuries. Liver function parameters including ALT,AST,LD L,CRP were measured and analyzed statistically.?Results ALT and AST were increased at 30min after injuries, but no statistical significance(P0.05). 1h later, these two parameters were significantly increased all the time after injuries(P0.05;? P0.01),except that AST showed no difference at 9h after injuries(P0.05). For LD L,there was no significant difference at 9h after injuries, otherwise the wounded animal showed increased level of LD L (P0.05,P0.01). There was no difference for other parameters measured following injuries.?Conclusion The ALT,AST and LD L are sensitive parameters for the detection of liver function which can be used for diagnosis.