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《Journal of Traumatic Surgery》 2008-03
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Anti-aging effects of theanine on aging model mice induced by D-galactose

LIU Xian-ming,LI Yue-fen,LI Guo-ping(Department of Neurosurgery,Municipal Hospital of Qingdao,Qingdao 266071,China)  
Objective To study the anti-aging effects of theanine on aging model mice induce by D-galactose.Methods After making the aging models by injecting D-galactose,we determined the learning and memory abilities by "Y" maze and detected the activities of SOD,MDA,NOS and AchE by enzymatic method in brain tissue of the aging mice.Results Compared with model group,theanine significantly increased the learning and memory abilities of aging mice.It also increased the activities of SOD and AchE,decreased the amount of MDA(P0.05,P0.01).Conclusion Theanine has the anti-aging effects on aging model mice and its mechanism may be related to its inhibitory effect on free radical and enhancement of central cholinergic fuction.
【CateGory Index】: R285
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