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《Acta Sericologica Sinica》 2005-04
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Cecropin Biotechnology and its Application

HUANG Ziran~1 HUANG Yadong~1 WEN Liufa~1 ZHENG Qing~1 LIAO Fupin~1 HU Jianxiong~2 HUANG Guoqing~2 JIANG Lihua~2 HUANG Yongtong~2 LI Yunnan~3 LIANG Shuwa~3 PENG Zhongjian~3 DONG Jiaxi~3 XIA Fenggeng~3 CHEN Songbin~4 (~1South China Agricultural University,Guangzhou 510642,China;~2Shenzhen Yiping Bio.Engineering Co.Ltd.,Shenzhen 518032,China;~3Guangzhou Microbiology Institute,Guangzhou 510630,China;~4Huasang Bio.Engineering Co.Ltd.,Guangzhou 510520,China)  
Cecropin from Chinese oak silkmoth Antheraea pernyi has a broad spectrum bactericidal effect.According to its amino acid sequence the cecropin D and CAD gene was designed,synthesized,and transferred into plants,such as tobacco,tomato,potato,rice,mulberry tree and citrus etc.Diseases resistant varieties were bred.Cecropin CAD gene was transferred and expressed in yeast Saccharomyce cervisiae.The recombinant cecropin produced by fermentation was used as an additives replacing the antibiotics to feed the chickens,young pigs and prowns.And well effects of the recombinant cecropin were obtained on preventing of diseases,raising survival rate,increasing body weight and reducing the rate of food/meat.Therefore its application in production has been started.More over,cecropin can be confected as mouth disinfectant and vagina sterilizer defending the disease of respiratory and vagina inflammation.Cecropin reagent has been mixed with growth factors to produce many kinds of cosmetics and put in the market,obtaining well economic effects.
【Fund】: 广东省成果孵化基金项目(编号98FF14);; 广州市科技局攻关计划项目(编号2002Z2-E0041)
【CateGory Index】: S886.9
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