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《Science of Sericulture》 2008-03
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Anti-fatigue Effects of Bioactive Peptides From Male Silkworm Moth on Mice

ZHANG Lu1,2 TANG Dao-Bang1 XIAO Geng-Sheng1* LIU Ji-Ping2 XU Yu-Juan1 WEN Jing1(1 Sericulture & Farm Product Processing Research Institute,Guangdong Academy of Agricultural Sciences,Open Access Laboratory of Agricultural Product Processing,Guangzhou 510610,China;2College of Animal Science,South China Agricultural University,Guangzhou 510642,China)  
Bioactive peptides were prepared from the male silkworm moth,which had been used for eggs production.The anti-fatigue effects of bioactive peptides on mice,including the survival time of loaded-swimming,and concentration of blood lactate,blood urea nitrogen(BUN) and liver glycogen,were investigated in this paper.The experiment results showed that the treatment of bioactive peptides had no effect on the body weight and status of mice(P0.05).Compared with that of control group [(482.3±136.6) s],the survival time of loaded-swimming of middle and high dose group [(744.0±233.9) s,(816.6±270.4) s] were prolonged significantly(P0.01).Compared with that of swimming control group [(10.34±0.64)mmol/L],the concentration of BUN of middle and high dose group [(8.54±0.42) mmol/L,(9.04±0.81)mmol/L] were decreased significantly(P0.05,P0.01).And compared with that of swimming control group [(5.85±0.60)mg/g],the concentration of liver glycogen of middle and high dose groups [(7.91±0.65)mg/g,(7.82±0.73)mg/g] were increased significantly(P0.01).The above results indicated that the exercise endurance and anti-fatigue capability of mice,administrated with bioactive peptides from the male silkworm moth,can be strengthened.
【Fund】: 广东省社会发展计划项目(编号2007B031100004)
【CateGory Index】: R285.5
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