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《Pratacultural Science》 2009-04
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Research progress on toxicity, harm and prevention of Oxytropis

LI Quan,LI Jun-nian,TAO Shuang-lun,DING Yu-jing,HE Lan,WANG Zheng(College of Biology and Environmental Sciences, Jishou University, Jishou 416000, China)  
The research progress on the source, toxicology, harm to livestock and prevention and treatment methods of Swainsonine, which was the main toxic component of Oxytropis, was reviewed in this paper. The swainsonine mainly originated from the metabolism of Oxytropis endophyte, and its concentration was related with the nitrogen fixation of nodule, but not genetic characteristics. Swainsonine was transported to the tissue organ of livestock by blood and inhibited mannosidase activity when accumulated to a certain degree, which leads to the degeneration of cells in the form of cavitation. Then, the immune, health, mental behavior, digestion, absorption, growth, propagation and introduction of livestock were influenced. At present, the preventive methods were rotational grazing, isolation and anorexia, and the main treatment to this disease was to treat the livestock with medicine.
【Fund】: 国家自然科学基金资助项目(30570285);; 湖南省自然科学基金项目(05JJ40033);; 湖南省教育厅重点资助项目(03A037)
【CateGory Index】: S452
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