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《Journal of Changchun University of Chinese Medicine》 2015-04
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Study on antibacterial activity of Gentianine

LI Wei;WANG Linlin;YU Heshui;ZHANG Liyuan;SONG Xinbo;Tianjin University of Traditional Chinese Medicine;  
Objective Studying the bacteriostatic activity of gentianine in order to provide a basis for developing an active ingredient of Chinese herbal medicine monomer treating disease of department of gynaecology which induced by bacteria or fungi. Methods Using double dilution method combining with Colony counting method. Results Gentianine could inhibit the growth of Escherichia coli,Staphy lococcus aureus,P. Aeruginosa and Monilia albican,and the MIC to Escherichia coli,Staphy lococcus aureus and P. Aeruginosa is 0. 8 750- 1. 750 mg / m L,to Monilia albican is 0. 9037- 1. 807 mg / m L. Conclusion Gentianine has a certain inhibition to Gram-negative and Gram-positive bacteria.
【Fund】: 天津市科技计划项目(12TXGCCX03800)
【CateGory Index】: R285
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