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《Journal of Changzhi Medical College》 2009-01
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Effects of Puerarin on Bone Mineral Density and IL-6 in Ovariectomized Rats

Li Xujiong,Zhang CuiyingPhysiology departement of Changzhi medical college  
Objective: To investigativ the effect of the puerarin on body mineral density(BMD)and IL-6 in ovariectomized(OVX)rats.Methods: Thirty virgin female Wistar rats of four months old were divided into four groups randomly.After ablating bilateral ovarian,Wistar rats were drunken remedium and its effects on osteoporosis were observe.On the twelfth week,blood was collected to assay estrogen(E),IL-6 levels.The bone densities of the femur were measured.Results: Rats in OVX group displayed the lower bone densities and the higher IL6,lower serum levels of estrogen.After drunken puerarin,compared with OVX group,rats in OVX+PUE group had lower levels of IL-6 and higher bone densities.Conclusion: Puerarin could promote the bone densities buildup and reduce serum IL-6 in OVX rats.
【Fund】: 山西省教育厅高校实验室建设资金资助项目(2005117)
【CateGory Index】: R285.5
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