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《JOURNAL OF CHANGZHI MEDICAL COLLEGE》 1998-02
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The Experimental Study of DaChengQi Decoction Resisting Free-radical Damage

Guo Chunhua Lin xiuzhen Zhang Caili ChangZhi medical college(046000),  
In order to study the effect of DaChengQi decoction with protecting intracellular organelle,endotoxin was given to rabbits intravenously twice and produced generalized Shwartzman reaction(GSR).These animals were served as disseminated intravascular colagulation(DIC) model,serum and hepatic mitochondria lipid peroxides(LPO) were measured.The results showed LPO of DIC model group increased markedly than control group.Dexamethasone group was similar to control group,although DaChengQi decoction group was higher than control group they had no statistical difference(P0.05).Electronmicroscope result was in concordance with biochemical test.It indicate DaChengQi decoction can resist LPO damage induced by endotoxin and preserve intracellular organelle,reduce endotoxin injury to body.
【CateGory Index】: R285.5
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【Citations】
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【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Yang Yuzhong;Wang Xinfang;Guangdong Province Hospital of combination of traditional Chinese and Western Medicine;;Clinical Effect Observation on the Time of Large Chengqi Decoction Rheum Decocting Later in Patients with Yangmingfu-visceraexcess[J];世界中医药;2014-07
2 JIAN Lin-hong;LI Yong-min;XIAO Mei-ying;Hunan Academy of Chinese Medicine;;Comparison of pharmacology between ultra- micro quickly dissolved preparation of Dachengqi decoction and traditional decoction[J];湖南中医杂志;2014-04
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5 FAN Xin-rong ZHU Wen-feng WU Can-rong WANG Rong-tian HUANG Gui-hua LIU Tian Hu'nan College of Traditional Chinese Medicine;Research on Absorbability of D-xylose in Small Intestine and Activity of Liver Na~+-K~+-ATPase of Rats with Taiyin or Yangming Disease[J];上海中医药大学学报;2007-04
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7 YUAN Tian-shuo,CHEN Yue-bin,CHEN Wei-chao(Traditional Chinese Medical Hospital of Tiantai county,Tiantai 317200,China);Influence of Xinmaitong capsule on total ischemia burden in patients with coronary heart disease and its therapeutical mechanism[J];现代中西医结合杂志;2006-14
8 LIU Jian-xuan,WU Ying-jie,CHEN Ying(Academy of Traditional Chinese Medicine and Materia Medica of Jilin Province,Changchun 130021,China);Study on the Effect of Jiaotongxinshen Capsule on Pharmacodynamics[J];特产研究;2005-04
9 WU Quanlong,PENG Qinghua,ZHAO Haibin,et al Department of Ophthalmology,the First Affiliated Hospital of Hunan College of Traditional Chinese Medicine,Changsha 410007,China;An experimental study on the protective effects of qingguangan(青光安)granule on retina in rabbit eyes with acute ocular hypertension status[J];中国中医眼科杂志;2004-04
10 SONG Xiang-fu 1, ZHANG Jing-chun 2, WU Xiao-hui 1 (1. Department of Laboratory Animal, School of Pbulic Health, Jilin University, Changchun 130021,China;2. Department of Laboratory,China-Japan Union Hospital, Jilin University,Changchun 130031, China);Effects of Rhodiola extracts on lipideperoxygen and apoptosis of hepatocytes in aged mice[J];吉林大学学报(医学版);2004-05
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