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《Journal of Northeast Agricultural University》 2007-02
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Histomorphology of development,lactation and involution of mice mammary gland(Ⅰ):Changes of common histomorphology

LI Jian,LI Qingzhang(Key Laboratory of Dairy Science,Ministry of Education;College of Food Science,Northeast Agricultural University,Harbin 150030,China)  
The changes of common histomorphology of mice mammary gland during virgin,pregnant,lactation and involution were studied to lay the groundwork for lactation biology and regulation of mammary gland function.The mammary gland tissue from various stages was made to paraffin section and hematoxylin-eosin(HE) staining,and the tissue structure was observed under common microscope.During the period before sexual maturation and stationary phase of mammary gland,the primary tissues were connective tissue,scattered output ducts,atrophied gland alveoluses and stuffed cell cables.The gland alveolus and condulet were simple cuboidal epithelium.After sexual maturation,secretory portion and duct began to develop,especially during the gestation period.Under the influence of progesterone,glandular tissue developed rapidly and gland alveolus and lobule were surrounded by interstitial substance.During the lactation,the mammary gland was full of activity.The later period of lactation,gland tissue got smaller,the lactation stopped and turned to stationary phase.During involution and the old age,the tissue of the mammary gland began to regress and replaced by the connective tissue and fat.The tissue structure of mice mammary gland during virgin,pregnant,lactation and involution showed regular periodical change.
【Fund】: 国家自然科学基金项目(30671538);; 黑龙江省自然科学基金重点项目(ZJN0504)
【CateGory Index】: Q954.6
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