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《Contemporary Medicine》 2009-20
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The Correlation Between MSCT Perfusion Parameters and Clinical Staging in Nasopharyngeal Carcinoma

Yu-lin LIU,Xian CHEN,Zhao-xi ZHANG,Dong-ping DU,Ning XU,Chun-lin JIANG,Qiong-hua TU Department of Radiology,Hubei Cancer Hospital,Wuhan 430079,China  
Objective To explore the correlation of MSCT perfusion parameters and clinical staging in nasopharyngeal carcinoma (NPC). To investigate the clinical utility ofMSCT perfusion for NPC. Methods 35 NPC patients proved by pathology were underwent MSCT perfusion imaging of nasopharynx with Mx8000 Quad CT. The perfusion data of tumors such as blood flow(BF),peak enhancement index(PEI),time to peak(TTP) and blood volume (BV)were measured. The correlation of MSCT perfusion parameters with TNM staging was analysed using Spearman rank correlation analysis. Results In 35 cases of NPC,BF,PEI,TTP and BV of NPC lesion were (51.65 ±3.25).ml.100g-1.min-1,(28.65 ± 1.52)HU,(30.68 ± 2.01)s,(12.49 ± 1.07) ml.100g-1 respectively,PEI and BV in NPC were correlated positively with its clinical stage (rs=0.46,rs=0.53,P0.05),BF and BV were correlated positively with T stage of NPC (rs = 0.37,rs = 0.42,P0.05),other perfusion values have no correlation with T stage or N stage. Conclu-sion It had characteristic manifest of NPC in perfusion image. PEI and BV have positively correlation with clinical staging of nasopharyngeal carcinoma. The MSCT perfusion valcan reflect some characters of NPC staging.
【CateGory Index】: R739.63
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