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《Contemporary Medicine》 2009-35
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The experience of psychro-circulation microwave to treat solid tumor and experiment of treat pork liver

He xuxun,Xia yueqing,Sun xueqing,Chen yan,Dong zhengyu,Jin cheng Department of oncology,the Cancer Hospital of Yan cheng,Yan Cheng,Jiangsu Province,224003 China  
Objective To explore the technical parameters of microwave coagulation therapy with better therapeutic effect in solid tumor.Methods Experiment of treating pork liver ex vivo by using psychro-circulation microwave coagulation therapy was done,and on the basis of its result we treated 11 patients with tumor using psychro-circulation microwave with 70W~75W and 10~15minutes.The tumor included liver cancer,lung cancer and renal carcinoma.Results The clotting extent of pork liver ex vivo was described as follows:70W,single knife,3cm×2.3cm,3cm×3cm,4cm×3.2cm corresponded to 5min,10min,15min respectively;75W,single knife,4cm×3.8cm corresponded to 15min;70W,double knives,4cm×6cm corresponded to 15min.The recent curative effect of 11 patients was CR 18.2%(n=2),PR 36.4%(n=4),SD 27.3%(n=3),PD 18.2(n=2).Conclusions Psychro-circulation microwave coagulation treating solid tumor has explicit local effect,little invasive,less adverse reaction and it is convenient.Because of its good quality,most of solid tumor which can be located and punctured could use it.It also can be combined with chemotherapy.For tumor of liver,single knife,70W-75W,the maximum available extent is 3-4cm×3-3.2cm corresponded to 10-15min,so the suitable parameter is 70W,15min.Single knife treatment only once is feasible if the tumor's maximum diameter is shorter than 3cm;but if the tumor's maximum diameter is longer than 3cm,single knife treatment exceeds one is pragmatic and it can elevate the effect.In a word,the reliable effect can be found if therapy is no dead zone and reasonable;if it has residual dead zone,it must be recurred or progressed.
【CateGory Index】: R730.5
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