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Objective To study the change of urine fluoride excretion after decreasing the iodine intake in the arer where the iodine and fluorine content is normal. Methods Stop iodized salt supply of 360 residents at the survey point for two nonths.Determine the urine fluoride and urine iodine when the study beginning ang two months later.Analysis the correlation. Results After stopping to supply iodized salt, median urine iodine paired difference is 95.86 μg/L,t=7.78,P0.01. The median urine fluoride paired difference is -0.15 mg/L,t=-3.31,P0.01. Conclusion After stopping to supply iodized salt, urine iodine content of the study population significantly reduced. At the same time, the urine fluoride content increased significantly and there is no difference between male and female. The results show that the discharge between iodine and fluoride in the body can antagonistic each other.
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