Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Chinese Physician》 2002-03
Add to Favorite Get Latest Update

Changes of Serum Endotoximia and Interleukin-6 Levels Before and After Treatment at Intestine Depollution and Adjustment Intestine Microenvironment in Patients With Liver Cirrhosis

CHU Yan-jun,LU Yan-ru,GUO Chang-qing.Department of Gastroenterology,The First Affiliated Hospital,Hennan Medical University,Zhengzhou 450052,China  
Objective To observe the changes of serum endotoxin and interleukin-6 level before and after treatment at intestine get rid of filth and adjustment intestine microenviroment in patients with advanced stage liver cirrhosis and to oberserve the incidence of spontaneous bacterial peritonitis(SBP) and to research a method that can more efficient reduce the incidence of SBP.Methods Group A was given conventional treatment such as protection liver,supplement human albumin and uragogue;goup B was given FPA 0 2g tid po,continuous three days on the basis of two weeks conventional treatment,group C was given Tab comfort get 0 5g tid po,Changtai orally taken liquid,10ml tid po,lactulose 10ml tid po, for all 8 weeks,on the basis of group B treatment after pausing use FPA.Results Serum endotoxin and interleukin-6 levels in group A was not significantly changes after treatment,,SBP incidence was higher than both group B and group C;at group B,serum endotoxin and interleukin-6 levels decline,SBP incidence significantly drop afer treatment,at group C,serum endotoxin,interleukin-6 level and SBP incidence significantly drop,the difference was significant at statistics as compared with group A and B.Conclusions The treatment at intestine get rid of filth and adjustment intestine microenviroment can effectively reduce serum endotoxin and interleukin-6 levels and can significantly reduce the incidence of SBP.
【CateGory Index】: R575.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 ZHOU Hong-yu,ZHOU Guo-hua, LENG Ming-fang,et al.Department of Digestive Disease,169th Hospital of PLA,Hunan Province,Hengyang 421002,China;A study on small intestinal bacterial overgrowth in patients with hepatic cirrhosis[J];Chinese Journal of Difficult and Complicated Cases;2011-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 WU Gang, YAN Ge, WU Guo-yi,et al. (Institute for Viral Hepatitis, Chongqing University of Medical Sciences,Chongqing 400010,China);The study of N-acetylcysteine-restrained apoptosis of human hepatocyte in vitro[J];Chongqing Medical Journal;2005-01
2 WANG Yun-ying,YE Yue-hong,Li Xing-lu,et al.(The Second Affiliate Hospital,Chongqing university of Medical Sciences,Chongqing 400010,China);Study on changes of coagulation factors in the treatment of chronic severe hepatitis with plasma exchange by using FFP or FP[J];Chongqing Medical Journal;2005-11
3 Wu Gang, et al Research Institute for Viral Hepatitis, Chongqing University of Medical Sciences;THE STUDY OF LIPOPOLYSACCHARIDE-INDUCED APOPTOSIS OF HUMAN HEPATOCYTE IN VITRO[J];Journal of Luzhou Medical College;2004-04
4 Wang Jianjun; Tong Wenbin;Gu Guizhen;Li Zefen (Department of Microbiology, Luoyang Medical Collegr * Luoyang Health School)Xu Linngzhen; Li Dongru; Deng Tongmei; Yue Yutao (Departinent of Infectious Disease, Affiliated Hospitel of Luoyang Medical college);Analyses of determining plasma endotoxin of hepatopaths[J];Journal of Luoyang Medical College;1994-02
5 ;内毒素对离体鼠肝细胞的致伤作用[J];WORLD CHINESE JOURNAL OF DIGESTOLOGY;1999-05
6 ;IL-6和 SIL-6R 在病毒性肝炎中的关系及其致病作用[J];World Chinese Journal of Digestology;2000-12
7 ZHANG Da zhi,REN Hong,ZHANG Ding feng (The Institute of Viral Hepatitis,Chongqing University of Medical Sciences,Lingjing Road74,Chongqing,400010);Studies on LPS Induces Apoptosis of cells[J];Modern Medicine Health;2004-08
8 REN Da-bin,HAN De-wu,ZHAO Yuan-chang (Department of Pathophysiology,Shanxi Medical University,Taiyuan 030001,China);Effect of intestinal endotoxemia on hepatic energy metabolism in acute liver failure[J];Chinese Journal of Pathophysiology;2001-09
9 Wu Xirun Ma Xuehui Ying Lei *Department of Gastroenterology,The second hospital,Shanxi Medical University,Taiyuan 030001;STUDY ON LIVER REGENERATION IN FULMINANT HEPATIC FAILURE IN RATS[J];Chinese Journal of Hepatology;1997-04
10 Jiang Li, Li Yuehua, Qi Xiaohong,et al. Department of Pathophysiology, Nanjing Medical University. Nanjing, 210029;The Preventative effect and Mechanism of Danshensu on Endotoxin Induced Liver Injury[J];Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases;1999-02
【Co-references】
Chinese Journal Full-text Database 3 Hits
1 ;Study on Relationship Between Small Intestinal Bacterial Overgrowth and Disease of Digestive System[J];Journal of Henan University of Science & Technology(Medical Science);2007-04
2 ZHOU Hong-yu,ZHOU Guo-hua.(Department of Gastroenterology,169 Hospital of PLA,Hengyang 421002,China);The Relationship between Antibiotics and Portal Hypertention in Liver Cirrhosis[J];Medical Recapitulate;2007-13
3 LIU Wei, JIANG Yi-bin, ZHONG Liang,et al. Department of Gastroenterology, Huashan Hospital, Fudan University, Shanghai 200040,China;Small intestinal bacterial overgrowth and endotoxinemia in patients with chronic liver disease[J];Chinese Journal of Digestion;2005-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved