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《Journal of Chinese Physician》 2006-04
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Treatment of avascular necrosis of femoral head by core decompression and autograft of mesenchymal stem cells

WANG Wu-zhou,XING Geng-yan,ZHANG Ke-chao,MA Li-gang,BAI Xiao-dong,LI Bing.Department of Orthopedics,General Hospital of the Chinese People's Armed Police Forces,Beijing 100039,China  
Objective To observe the therapeutic effect on the treatment of avascular necrosis of femoral head by core decompression with autograft of mesenchymal stem cells(MSCs).Methods Nineteen patients with avascular necrosis of femoral head,including 8 cases of phase I,6 cases of phase II and 5 cases of phase III based on ARCO classification,were treated with core decompression with autograft of MSCs.Results The patients were followed up for one year.The average ratio of necrosis zone diminished from 31.88% to 13.18%.The Harris hip score was increased significantly.Conclusion The treatment of core decompression with autograft of MSCs is safe and effective,and it deserves to application in early necrosis of femoral head.
【Fund】: 国家自然科学基金资助项目(30371430);; 首都医学发展科研基金资助项目(2002-3037)
【CateGory Index】: R687
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