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Protective effect of neutral mucopolysaccharide on RBC membrane during ischemia reperfusion brain damage in gerbil

Ding Suju, Zheng Huimin, Zhang Renqin, Hou Xiaojun, Deng Benqiang (Department of Neurology, Changhai Hospital, Second Military Medical University, Shanghai, 200433)  
Objective: To study the protective effect of neutral mucopolysaccharide (NM) on RBC membrane during ischemia reperfusion brain damage in gerbil. Methods: The functional changes of red blood cell immune adherence (RCIA) and the content of red blood cell superoxidate dismustase (RBC SOD), red blood cell malonialdehyde (RBC MDA) were observed by means of cerebral ischemia reperfusion in gerbil. Results: NM recovered the function of RCIA; increased RBC SOD; decreased RBC MDA. Conclusion: NM regulates the function of RCIA by antioxygenic effection, and has the protective effect on RBC membrane during ischemia reperfusion brain damage.
【Fund】: 上海市自然科学基金
【CateGory Index】: R965
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