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《Academic Journal of Second Military Medical University》 2001-04
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Detection and genetic analysis of TT virus in hemodialysis patients

NI Wu 1, REN Hao 2, MIAO Xiao Hui 1, QI Zhong Tian 2, YE Chao Yang 3 (1. Department of Infectious Diseases, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China; 2. Department of Microbiology, Department of Basic Medicin  
Objective: To study the prevalence and pathogenesis of TT virus (TTV) in hemodialysis patients. Methods: Serum TTV DNA was tested in 69 hemodialysis patients from our hospital by nested PCR using primers from a conservative region of TTV genenome, genetic analysis and detection of hepatitis C virus antibody (anti HCV) and the levels of alanine aminotransferase (ALT) were also carried out simultaneously. Results: The overall prevalence of TTV viremia was 27.5%. The PCR amplified gene fragment from one patient was sequenced, and its gene sequence homologies with GH1,TA278, TTVCHN1 and TTVCHN2 ranged from 89% to 100%, its deduced amino acid sequence ranged from 87% to 100%. There was no significant difference of TTV prevalence between anti HCV positive and negative patients. No significant elevation of ALT was found in all patients. Conclusion: High prevalence of TTV infection is found among hemodialysis patients, and TTV infection has no significant association with HCV infection or elevation of ALT. [
【Fund】: 国家自然科学基金!资助项目 (396 80 0 18)
【CateGory Index】: R459.5
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Zhou Yusen, He Zhongping, Dong Jingfang, Wang Haitao Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071;Cloning and sequencing of partial gene from TTV isolate in China[J];BULLETIN OF THE ACADEMY OF MILITARY MEDICAL SCIENCES;1998-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Geng Lixia,Wang Yongfu,Guo Cunlin,Wu Rentana (The nedicine of first assistant hospital of Baotou Medical college, Baotou 014010,China);The Prevalence,Genotype of TTV in 50 Patients with Chronic Liver Disease Ofunknown Etiology[J];Journal of Baotou Medical College;2000-04
2 LI Jun1,LEI Xin-li2,CHEN Jian-li3,CAO Chun-bao4,WANG Ya-nan4,MA Xiu-min4,WU Yue-ming1,DING Jian-bing4(1.The Center for Diseases Control and Prevention of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang 830002,China;2.Urumqi Municipal Traditional Chinese Medicine Hospital,Urumqi,Xinjiang 830000,China;3.Shihezi Municipal People's Hospital,Shihezi,Xinjiang 832000,China,4.Pre-clinical College of Xinjiang Medical University,Urumqi,Xinjiang 830054,China);Primary Study on TTV Infection in Aged People[J];Endemic Diseases Bulletin;2009-03
3 Yang Zhiguo,Xu Jiazhang ,Zhou Yusen, et al. Department of Infectious Diseases, The 81st Hospital of PLA, Nanjing,China ,210002.;Clonning and sequencing of partial gene of TTV from Nanjing in China[J];;1999-02
4 ZHANG Rui, ZHANG Xu qing, GU Chang hai, HUANG Yang ping, WANG Hai tao (Infectious Diseases Research Center of PLA, Southwest Hospital, Third Military Medical University, Chong qing 400038);Detection of TTV-DNA and serum clinical characteristics of TTV hepatitis[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;2000-01
5 JI Xin-Ying 1, FU En-Qing 1, ZHOU Yu-Sen 2, WANG Hai-Tao 2, YANG Wei-Song 1 1Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China, 2Institute of Microbiology and Epidemiology, Chine;Partial sequence variation of TTV in several regions of China[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;2000-07
6 LE Mei zhao,XU Jia zhang,YANG Zhi guo,SONG Xiao ming (81st Hospital of PLA, Nangjing 210002,China.);Ultrastructural changes of liver in patients with hepatitis TTV[J];Journal of Chinese Electron Microscopy Society;2001-06
7 He Zhongping ,Zhou Yusen,Dai Wangsu, et al . Beijing Ditan Hospital , Beijing , 100011. Institute of Microbiology and Epidemiology , Academy of Military Medical Sciences . Beijing ,100071.;PRESENCE OF TTV DNA IN PERIPHERAL BLOOD MONONUCLEAR CELLS FROM PATIENTS WITH TTV INFECTION[J];Journal of Clinical Hepatology;1999-01
8 Yu jian guo , Han Ji ju , Xiao De ming, et al Department of infectious Diseases, 88th Hospital, Taian 271000.;PREVALENCE OF TTV INFECTION AND PARTIAL DNA SEQUENCE ANALYSIS OF TTV ISOLATES IN SHANDONG[J];Journal of Clinical Hepatology;1999-03
9 HUANG Xing,ZHAO Suyuan,ZHONG Yingna,et al.People's Hospital of Xinjiang Uygur Autonom_ous Region,Urumqi, Xinjiang 830001,China;Epidemiological investigation on TTV infection in sera of different population from Xinjiang[J];Guangxi Journal of Preventive Medicine;2002-06
10 ;广州地区献血者中输血传播病毒感染情况调查[J];Guangzhou Medical Journal;2002-06
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Zhou Yusen, He Zhongping, Dong Jingfang, Wang Haitao Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071;Cloning and sequencing of partial gene from TTV isolate in China[J];BULLETIN OF THE ACADEMY OF MILITARY MEDICAL SCIENCES;1998-02
2 Zhou Yusen; Wang Haitao; He Yuxian; Zhao Huiliu;Wang Huaichun; Chen Wei; Xu Jiag(Institude of Microbiology and Epidemiology, Beijing,100071)(Research Center of Beijing Ditan Hospital , Beijing 10011);GENOMIC ORGANIZATION OF CHINESE HEPATITIS G VIRUS (HGV) AND DISTRIBUTION OF HGV INFECTION IN CHINA[J];MICROBIOLOGY;1997-01
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