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Studies on Hyaluronate in Carbon Tetrachloride Induced Cirrhotic Rat Liver

Gao Feng;Cao Manlin;Kong Xiantao(Center of Clinical Immunology,Changzheng Hospital,Second Military Medical University,Shanghai,200003)  
Liver cirrhosis was induced in rats with carbon tetrachloride.Hyaluronate(HA)levels were measured in both serum and liver homogenate using ELISA.The results demonstrated a significant increase of serum HA levels that occurred early and in the late stage of liver fibrosis.The serum concentrations of HA in different stages paralleled the progressed liver damage.In contrast, no significant increase was seen in the liver homogenate level of HA in the early stage of liver fibrosis, but occurred in the late stage.The results suggest that immunoassay for HA in serum is a more sensitive index for liver cell damage and hepatic fibrosis.
【CateGory Index】: R575.202
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Chinese Journal Full-text Database 4 Hits
1 CHEN Xiaopeng,WU Tongsheng,HU Yehong,et al.Department of Internal Medicine,the First People's Hospital,Tongling,Anhui 24000,China;Long-term observation of CCL_4-induced live cirrhosis in rat[J];实用肝脏病杂志;2006-04
2 WANG Yu,CHENG Wei-Bo.ZHANG Yin-zhu,et al.Department of Pathology,West China School of Public health,Sichuan University,Chengdu 610041.;A STUDY OF CHRONIC INJURY MODEL INDUCED BY 10% CARBON TETRACHLORIDE.[J];现代预防医学;2006-05
3 YANG Kai-xuan,CHENG Wei-bo,WANG Wen-dong,et al.Department of Pathology,West China Second Hospital of Sichuan University,Chengdu,610041.;A STUDY OF CHRONIC INJURY MODEL INDUCED BY 40% CARBON TETRACHLORIDE[J];现代预防医学;2005-01
4 邓居有 2 李宜辉 1 胡 云 2;胆道肿瘤患者血清甘胆酸和透明质酸的变化[J];世界华人消化杂志;1999-09
China Proceedings of conference Full-text Database 1 Hits
1 ;Pathological observation of spirulina in prevented experiment Hepatic Fibrosis rats[A];[C];2006
Chinese Journal Full-text Database 2 Hits
1 Gao Feng;Kong Xiao-tao Wang Xiao-li,et al.(Depart ment of Clinical Immunology, Changzheng Hospital ,The Second Millitary College,Shanghai,200003);THE EXTRACELLULAR MATRIX AND LIVER DISEASE:A STUDY WITHENZYMOIMMUNOLOGICAL ASSAY[J];中华内科杂志;1994-02
2 Gao Feng, Kong Xiantao, Xie Yinghua, Wang Xiaoli, Fan Lieying, Tan jinxing( Center of Clinical Immunology, Changzheng Hospital, Shanghai, 200003);Extracellular Matrix in Liver: Experimental Study and Clinical Application[J];第二军医大学学报;1993-05
Chinese Journal Full-text Database 10 Hits
1 GAO Zhen1,LI Fengsen1,HALMURAT·Upur2,JING Jing1,XU Dan1(1.Research Department,National Clinical Research Base of Traditional Chinese Medicine,the Affiliated Traditional Chinese Medicine Hospital,Xinjiang Medical University;2.Integrated Traditional Chinese and Western Medicine Teaching and Research Section,College of Traditional Chinese Medicine,Xinjiang Medical University);Effect of cold and dry environment on hyaluronan and laminin in the model of chronic obstructive pulmonary disease[J];重庆医科大学学报;2012-09
2 LU Yong1,LI Fengsen2,JING Jing2,WANG Jing2,XU Dan2,GAO Zhen2 1.Orthopaedic Center Tradition,Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University,Urumqi 830000,China 2.National Clinical Research Base of Traditional Chinese Medicine,Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University,Urumqi 830000,China;Influence of Cigarette Smoking and Cold Dryness on Matrix Metalloproteinase and Airway Extracellular Matrix in Rat[J];科技导报;2011-29
3 LI Jin-tian,LIANG Jing,TIAN Yong-yan,LIU Yong-qi,LI Juan,REN Hong-yan,ZHANG Qian,ZHANG Yi(Gansu College of Traditional Chinese Medicine,Lanzhou 730000,Gansu,China);Effect of Qizhi Zhoufei Sugar-Free Granules on rat small airway remodeling suffered from COPD[J];中成药;2010-11
4 LIU Chun Yu, GU Zhen Lun, ZHANG Ke Ping, ZHOU Wen Xuan 1, GUO Ci Yi 1 (Dept of Pharmacology, Medical College of Suzhou University, Suzhou Institute of Chinese Meteria Medica, Shuzhou 215007 1 Hong Kang Health Care Association for HEALTH CARELTD , HongKong );Effect of flavonoids of Astragali complanali on liver librosis induced by DMN in rats[J];中国药理学通报;2004-01
5 Jiang Duyin Fu Xiaobing Research Department of Burn of Wound and Plastic Institute,The Fourth People's Hospital,Taizhou 225300;The clinical significance of measurement of serum hyaluronic acid concentration in severely burned patients[J];感染.炎症.修复;2002-02
6 GAO Hong, HUANG Yao-tian,ZHAO Li,et al.Xinjiang Provincial Crops Hospital,Chinese People's Armed Forces,Wulumuqi 830000,China;The extracellular matrix of the sternocleidomastoid muscle in the congental muscular torticollis: a histochemistry study[J];现代康复;2001-24
7 Wan Fujun,Zhang Quan,Lu Rong,et al. Department of Nephrology,The General Hospital of Mine Administration Bureau,Fuxin Liaoning,123000[;EVALUATION AND SIGNIFICANCE OF THE DETECTION OF SERUM LAMININ AND α_1 -MICROGLOBULIN OF THE PATIENS WITH CHRONIC RENAL FAILURE[J];中国现代医学杂志;2001-04
8 Wang hongman, Bai junhua The third people ' s hospital of Chongqing (400015);CLINICAL SIGNIFICANCE OF HYALURONIC ACID AND LAMININ LEVELS IN COPD PATIENTS[J];放射免疫学杂志;1999-06
9 Wang Yi, Li Jingge, Pan Lei, Bai Xuefan (Institute of Hepatology, Beijing Army General Hospital, Beijing 100700);Evaluation of the therapeutic effects of radix salviae miltiorrhizae on patients with chronic hepatitis by serum interleukin 6 and hyaluronic acid[J];军医进修学院学报;1999-04
10 Zhang Bo,Liu Shufen, Zhang Shaofu, et al. Jinan Military Region Hospital, Jinan 250031;THE STUDY OF SERUM LAMININ LEVEL AND ITS RELATIONSHIP WITH LUNG CANCER INFILTRATION[J];临床肿瘤学杂志;1996-Z1
Chinese Journal Full-text Database 5 Hits
1 YANG Kai-xuan,CHENG Wei-bo,WANG Wen-dong,et al.Department of Pathology,West China Second Hospital of Sichuan University,Chengdu,610041.;A STUDY OF CHRONIC INJURY MODEL INDUCED BY 40% CARBON TETRACHLORIDE[J];现代预防医学;2005-01
2 XU Qing zhong, LEI Ting wen, MA Xiao ping (Departmant of Biochemistry and Molecular Biology, Guiyang Medical College,Guiyang 550004,China);Content Changes of the Serum Albumin in Rats with CCl_4 Induced Liver Fibrosis[J];贵阳医学院学报;2002-02
3 Zhao Minghe et alTangShan Worker's Hospital, 063000;An Experimental Liver Cirrhosis Model Established in Rats[J];实验动物科学与管理;1998-02
4 Gao Feng;Cao Manlin;Kong Xiantao(Center of Clinical Immunology,Changzheng Hospital,Second Military Medical University,Shanghai,200003);Studies on Hyaluronate in Carbon Tetrachloride Induced Cirrhotic Rat Liver[J];第二军医大学学报;1994-04
5 Liu Yimin, et al.;Comparative histological study of liver fibrosis during subacute poisoning of some hepatic toxicants.[J];职业医学;1991-06
【Secondary References】
Chinese Journal Full-text Database 8 Hits
1 SU Dong-Na;WU Shi-Pin;Department of Infectious Diseases,Shenzhen People' s Hospital,the Second Clinical Medicine College,Jinan University;;Experimental research of therapeutic effect of Smad7 gene modified bone marrow mesenchymal stem cells on liver cirrhosis rats[J];中国免疫学杂志;2016-05
2 XIONG Yao-bin;FU Ying;YU Hong;ZI Xiao-fei;YANG Hui;Jiangxi Academy of Medical Sciences;The Second Affiliated Hospital of Nanchang University;;Effects of Liquid Extract of Sarcandra Glabra to Anti-hepatic Fibrosis in Rats[J];江西中医药大学学报;2015-01
3 CHEN Li;ZHANG Lingyun;LAI Chun-hua;Department of Pharmacy,Third Hospital of Nanchang City in Jiangxi Province;Department of Pharmacy,First Hospital of Nanchang City in Jiangxi Province;;Study on protective effect of Qinggan Yizhi Tang in treating chronic liver injury[J];江西医药;2014-11
4 LI Meng;ZHAI Ya-nan;WANG Jing-jing;MENG Xia;SUN Quan;CHEN Bo-an;LU Jing;Capital Medical University;;Establishment of a mouse model of chronic hepatic injury induced by low dose carbon tetrachloride[J];中国实验动物学报;2014-04
5 XU Peng;TAN Wei-feng;LIU Bo;XIE Zhen;CAO Yi;ZHOU Nian;Department of Pharmacology,Jiangxi University of TCM;;Model Comparison in Liver Injury in Mice Induced by CCl_4[J];江西中医药大学学报;2014-03
6 TIAN Zheng-liang;DENG Xiu-na;LU Guan-chao;WANG Xiao-hua;Shaanxi College of Traditional Chinese Medicine;People's Hospital of Changle County,Weifang,Shandong;Fuping County Hospital,Shaanxi;;Experiment study on “Ruangan Xiaogu Decoction”for the treatment of cirrhosis in rats[J];上海中医药杂志;2014-04
7 ZHANG Jing;PING Jian;CHEN Hong-yun;Institute of Liver Diseases,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;Key Laboratory of Liver and Kidney Diseases,Ministry of Education;Department of Traditional Chinese Medicine,Changhai Hospital Affiliated to Second Military Medical University;;Preventive effects of Yiguanjian decoction on CCl_4-induced fatty liver in rats[J];中西医结合肝病杂志;2014-01
8 TAO Lin;JIANG Hai-xing;QIN Shan-yu;JIN Qun-xin;HUANG Xue;GUO Xiao-yun;TAN Zhi-rou;TANG Guo-du;Department of Gastroenterology,the First Affiliated Hospital,Guangxi Medical University;;Effect of Mesenchymal Stem Cells Transplantation on Anti-Hepatic Fibrosis in Rats and Its Mechanism[J];广西医学;2014-02
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