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《Endemic Diseases Bulletin》 2010-02
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Clinical Analysis of Involved Organs Besides Gastro-intestine after Rotavirus Infection in Infants and Young Children

CHEN Chun-hua, REN Xiao-mei, WANG Jian-rong(The 5th Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China)  
Objective To study clinical manifestations of organ damage besides gastro-intestine after rotavirus (RV) infection in infants and young children. Methods ELISA was taken to detect feces for RV antibody of 276 children with acute diarrhea in the hospital from January 2007 to October 2009. All patients were divided into RV IgM positive group (detected group, 112 children)and negative group (control group, 164 children). A retrospective analysis was carried out to compare general condition, intestinal symptom, manifestation outside the intestine and laboratiory examination between the two groups. Results There was statistical difference in incidence of organ damage besides gastro-intestine between the two groups (P=0.027 1) No difference was found in simultaneous phenomenon (dehydration, electrolyte disturbances, and acid base-equability derangement, P0.05). It indicated that there was no relationship between the incidence and patients' condition. Statistical difference in incidence of hepatic damage was observed in different age stages (≤1 year-old and 1 year-old) in the detected group(P=0.013 0), that suggested the lower age for rotavirus infection, the higher incidences of liver damage. Differences were detected in incidences of involved organs in two groups, respectively. Conclusions Clinical manifestations of organ damages besides gastro-intestine after RV infection are most of delitescence and sub-clinic. It should think highly of whether there are organs involved besides stomach and intestine in the diagnosis and treatment, effectively symptomatic treatment must be administered positively, so that the patients will get good prognosis.
【CateGory Index】: R725.1
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