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《Chinese Journal of Medicinal Guide》 2007-05
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Sevoflurance vs Propofol in the Operative Induction of Cheilopalatognathus in Children

Guo Jian-zhong (Department of Anesthesiology,Boai Hospital of Zhongshan City,Zhongshan 528403,China)  
Objective:To compare the induction characteristics of sevoflurane inhalation with intravenous propofol in pediatric surgery.Methods:30 children patients(ASA physical statusⅠandⅡ)undergoing selective operations were randomly allocated to re- ceive induction by inhalation of sevoflurane or intravenous of propofol.BP、HR and SpO_2 were recorded before induction of anesthe- sia,after induction,immediately after and one minute after tracheal intubation.Time to consciousness loss,restlessness,breathholding, laryngospasm,bronchiospasm,nausea and vomiting were also recorded.Results:The times to loss of consciousness in the group of propofol and group of sevoflurane were(35.5±11.7)s and(38.5±11.4)s,respectively.There was no significant difference between the two groups.BPs after induction or tracheal intubation in both groups,compared with before induction,were no significant change. But the changes in HR were significantly different between two groups(P0. 05),Compared with before induction,HBs in group of propofol were increased significantly(P0. 05),and HRs in group of sevoflurane were significantly decreased(P0.05).Restless- ness was more common during induction with sevoflurane than propofol(46% vs.20%,P0.05).No incidence of breathholding,la- ryngospasm,bronchiospasm,nausea and vomiting were noted in both groups. Conclusion:Both propofol and sevoflurane can be used effectively and safely for induction of anesthesia in pediatric surgery.But heart rate was increased during induction with propofol and Excitatory movement was more common during induction with sevoflurane.
【CateGory Index】: R782.054
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