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《Chinese Journal of Medicinal Guide》 2008-09
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Clinical Study on Docetaxel Combining Cisplatin and 5-Fluotreating Advanced Gastric Cancer

Zhang Wen-xia,Li Ji-jun (Department of oncology,Cangzhou central Hospital,Hebei,Cangzhou 061001,China)  
Objective:To evaluate the clinical effects and toxicity of DCF reginen(docetaxel plus 5-fluorouracil and cisplatin)chemotherapy in the treatment of advanced gastric cancer(AGC).Methdos:Twenty-seven patients with AGC treated with DCF regimen.Results:27 patients were evaluated with clinical response,including CR 2(7.4%),PR 14(51.8%),SD 8(29.6%),PD 3(11.5%).The totle effective rate was 59.2%. Median time to progression(TIP)was 6.4 months and median over all survival time was 10.2 months.The main side effects were:suppression of bone marrow in 22 patients(81.5%),nausea/vomiting in 23(85.2%),diarihea in 12(44.4%)and stomatitis in 9(42.3%).There was no death during the treatment.Conclusions:DCF reginen chemotherapy was well tolerated regimen in the treatment of AGC,which can relieve suffering and improve quality of life of patients.It can be used as the first-line therapy for relapsed advanced gastric cancer.
【CateGory Index】: R735.2
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【References】
Chinese Journal Full-text Database 1 Hits
1 WANG Xing-yuan,JIANG Bo,LI Cheng,et al.Department of Oncology,the People's Hospital of Guangan Sity,Guangan sichuan 638000,China;Clinical Observation on Treatment by Docetaxel for the Joint Topotecan in Advanced Gastric Carcinoma[J];West China Medical Journal;2009-09
【Citations】
Chinese Journal Full-text Database 1 Hits
1 ZHUO Li\|juan\+1, SHI Zuo\|lin\+2, GAO Mei\|qin\+1, LI Yan\|hui\+2, ZHENG Wei\+1 1.Division of Pathology, Fujian Medical University, Fuzhou 350004, China 2.Department of Pathology, Fujian Province Hospital, Fuzhou 350001, China;Expression of Thymidylate Synthase in Gastric Carcinoma and its Clinicopathological Significance[J];Journal of Fujian Medical University;2003-02
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Yang Qiumeng, Zhu Zhenggang, Yan Min, et al. Department of Surgery, Ruijin Hospital, Shanghai Second Medical University, Shanghai(200025);Establishing Clinical Indications of Intraoperative Peritoneal Hyperthermic Chemotherapy for Gastrointestinal Malignancy[J];Journal of Surgery Concepts & Practice;1998-01
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