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《Chinese Journal of Medicinal Guide》 2011-02
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Isolation and Identification of Chemical Constituents of Flavones from the Fruits of Acanthopanax Senticosus Harms

Liu Gui-ping~1,Li Zhi~2 (1 Harbin Pharmaceutical Group Sixth Pharm Factory,Harbin 150056,China; 2 Harbin Pharmaceutical prepared slices of Chinese crude drugs limited liability company,Haerbin 150088,China)  
Objective:To investigate the chemical constituents of the extract from thefruits of Acanthopanax senticosus Harms.Methods:The chemical constituents were isolated by various isolation methods(silica gel,ODS and HPLC column chromatography) and their structures were elucidated by the analysis of spectral data(NMR and MS).Results:Five flavones compounds were obtained and elucidated as following:luteolin(1)luteolin-4'-O-β-D -glucoside(2),luteolin-3'-O-β-D-glucoside(3),luteolin-7-O-β-D-glucoside(4),luteolin-7,3'-O-β-D-di-glucoside(5).Compound 2-5 were isolated from the Acanthopanax genus for the first time.Conclusions:Results five flavones compounds were obtained and elucidated as following:luteolin(1),luteolin- 4'-O-β-D-glucoside(2),luteolin-3'-O-β-D-glucoside(3),luteolin-7-O-β-D-glucoside(4),tuteolin-7,3'-O-β-D-di-glucoside(5).
【CateGory Index】: R284.1
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