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《Chinese Journal of Medicinal Guide》 2013-08
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Containing Anthracycline Cardiac Toxicity in Breast Cancer Patients with Chemotherapy

Zhang Zong-lin(Linyi City,Shandong Province,People's Hospital,Department of Pharmacy,Linyi 276000,China)  
Objective: To investigate the implementation of breast cancer patients with anthracycline chemotherapy,the toxic effects of myocardial tolerance treatment programs provide the basis for clinical chemotherapy.Methods: In our hospital for the study of breast cancer patients treated with chemotherapy,according to different chemotherapy regimens in patients divided into three groups(EC,AC,TC),for each group of patients during chemotherapy,the patient via ultrasound to evaluate cardiac morphology and function.Results: After two treatment cycles,EC group of 19 cases,3 cases of myocardial toxicity AC group,18 patients,three cases of cardiac toxicity,TC group,18 patients,1 case of myocardial toxicity.After four treatment cycles,EC 5 cases of myocardial toxicity AC group 5 patients had myocardial toxicity,TC group patients had myocardial toxicity.Conclusion: The three treatment methods,compared with the TC program,EC,AC regimen containing anthracycline myocardial toxicity in breast cancer patients with chemotherapy more significant(P0.05).EC and AC program of cardiac toxicity in patients with no significant difference(P 0.05).
【CateGory Index】: R737.9
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