Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Dalian Polytechnic University》 2008-04
Add to Favorite Get Latest Update

Antitumor and immunomodulating activity in vitro of the polysaccharide from Haliotis Discus Hannai Ino

WANG Li-sha,ZHU Bei-wei,SUN Li-ming,LI Dong-mei School of Biological & Food Engineering,Dalian Polytechnic University,Dalian 116034,China  
The polysaccharides AVP Ⅰ and AVP Ⅱ are extracted from the viscera of Haliotis Discus Hannai Ino and separated on Sephadex G-100 column.The polysaccharide contents of AVP Ⅰ and AVP Ⅱ are 66.41% and 51.84%,and the protein contents are 1.70% and 15.55% respectively.The molecular masses of AVP Ⅰ and AVP Ⅱ are 272 and 6 ku.AVP Ⅰ and AVP Ⅱ contain the same monosaccharide including rhamnose,glucose,xylose,mannose,galactose and fucose,the ratio of which for AVP Ⅰ is 1.00∶2.15∶4.00∶5.36∶33.18∶45.14,whereas AVP Ⅱ is 1.00∶1.46∶1.33∶4.98∶16.08∶12.51.AVP Ⅰ and AVP Ⅱ could restrain the proliferation of Hela and K562 cell in vitro.AVP Ⅰ and AVP Ⅱ can dose-dependently induce a significant increase in lymphocyte proliferation,phagocytosis of macrophage and natural killer cell activity in vitro.The abalone viscera can be used potentially as an immuneomodulating agent.
【Fund】: 国家国际科技合作重大项目(2006DFA32580);; 国家高技术研究发展计划项目(863计划)(2007AA091804)
【CateGory Index】: R151
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 7 Hits
1 CHEN Wen-xing;WU Hao;LU Yin;CHI Yu-mei Research Center of New and Marine Drugs,Nanjing University of Chinese Medicine,Nanjing 210029,China;Effect of polysaccharides from Hyriopsis cumingii on experimental transplanted tumor in mice and on activity of NK cells in vitro[J];Chinese Journal of Marine Drugs;2007-02
2 Xu Donghui Xu Shibo Wang Bing (Department of Pharmacy,Zhongshan University,Guangzhou 510275) Lin Yongcheng Shao Zhiyu (Department of Chemistry,Zhongshan University,Guangzhou 510275);A STUDY ON ANTI-TUMOR EFFECTS OF ABALONE POLYSACCHARIDE(AP) FROM HALIOTIS DISCUS HANNAI INO[J];Tropic Oceanology;1999-04
3 Chen Qianchao (Dept. of Pharmaceutics, Cancer Hospital Affiliated to Zhongsan Medical University, Guangzhou 510060);Extraction of Haliotis discushannai Ino. Polysaccharide and Experimental Study on Its Anti-tumor Action[J];Chinese Journal of Modern Applied Pharmacy;1998-01
4 Development Department, Shenzhen Neptunus Biotechnique Stock Co. Ltd. (Shenzhen 518054) Wang Bing Sun Yat sen University Jiang Jianmin, Xu Donghui, Xu Shibo, Shao Zhiyu and Lin Yongcheng;Antitumor Effect of Abalone Polysaccharide on Human Nasopharyngeal Cancer Inoculated on Nude Mice[J];CHINESE TRADITIONAL AND HERBAL DRUGS;2000-08
5 LI Sheng-jun,Lu Chang-long,LI Cheng,CAO Yan,YAN Jian-zhong(Department of Immunology,College of Basic Medical Sciences,China Medical University,Shenyang 110001,China);Immune-reinforcing effects induced by Porphyra polysaccharide on natural killer cell activity of mice[J];Journal of China Medical University;2007-02
6 Peng Wenduo,et al. (School of Life Sciences,Sun Yat-Sen University,Guangdong Guangzhou 510275,China);Physiological activities of enzymolytic extracts of abalone[J];Chinese Journal of Food Hygiene;2004-03
7 Xu Donghui, Wang Bing, Xu Shibo, ling Yongcheng, Shao Zhiyu (Zhongshan University, Guangzhou 510275);Effects of Abalong Polysaccharide on the Activity of the Peritoneal Macrophages and Delayed-type Hypersensitivity in Mice Bearing S_(180)[J];Journal of Chinese Medicinal Materials;1999-02
Chinese Journal Full-text Database 10 Hits
1 SUN Na et al(Shengyang Agricultural University,Shengyang,Liaoning 110161);Antitumor of Polysaccharide and its Application Prospect in Divestock[J];Journal of Anhui Agricultural Sciences;2007-20
2 LIU Shao1;SUN Lin2;YANG Ai-sheng2;CANG Dao-ping2;JIA Tao3;ZHAO Hou-ming3;LIAO Xing-hua1;CHEN Dong-chun1(1.College of Food Science and Technology,Hunan Agricultural University,Changsha 410128;2.Hunan Ruff Bio-Tech Co,Ltd.,Changsha 410005;3.Physics & Chemical Test Center of Jiangsu Province,Jiangsu Productivity Centre.Nanjing 210042,China);Analysis of Amino Acid Composition and Content in Andrias davidianus[J];Amino Acids & Biotic Resources;2007-04
3 KANG Ping,WANG Qiu-kuan(Key and Open Laboratory of Aquatic Product Processing and Utilization of Liaoning Province,Department of Food Engineering,Dalian Fisheries University,Dalian 116023,China);Enzymes Extracted from Abalone Viscera and Its Potential Application[J];Fisheries Science;2006-03
4 LI Dong-mei,TAN Feng-zhi,YANG Jing-feng,YIN Hong-ling,LI Tao,ZHU Bei-wei(College of Biology and Food Technology,Dalian Polytechnic University,Dalian 116034,China);Isolation,Purification and Identification of Polysaccharides from Abalone Viscera[J];Fisheries Science;2007-09
5 GUO Qing-dong1,LIN Chun-ying2,LIU Da-wei3,CHEN Hua1,CAI Jun-peng1,3(1.College of Light Industry and Food Science,South China University of Technology,Guangzhou 510640,China;2.Quan-zhou Entry-Exit Inspection and Quarantine Bureau,Quanzhou 362000,China;3.School of Bioscience and Bioengineering,South China Univresity of Techoology,Guangzhou 510640,China);Extra-cellular Factors from Bacteria Isolated from Abalone Farming Water[J];Fisheries Science;2008-06
6 MA Yu1,ZHANG Junxia2(1.Department of Secondary Technical and Vocation,Chengdu University,Chengdu 610015,China;2.School of Medicine and Nursing,Chengdu University,Chengdu 610015,China);Research Progress of Cancer-fighting Marine Animals[J];Journal of Chengdu University(Natural Science Edition);2009-03
7 Wang Yafei,Meng Qingyong Clinical Laboratory of Heping Hospital Affiliated to ChangZhi Medical College,Changzhi(046000),China;Effect of Gracilaria Gigas Harvey Polysaccharides (GHPS) on Natural Killer Cells Activity in Mice with Radiation Injury[J];Journal of Radioimmunology;2009-06
8 Xia Xue yan, Peng Ren xiu, Wang Zhi yong Department of Pharmacology, Medical College, Wuhan University, Wuhan 430071, China;The Effect of Angelica Sinensis Polysaccharide and Its Ingredients on Mice's Immunocompetence[J];Journal of Hubei Medical University;2001-03
9 Wang Zhi Cai Jun-peng Wen Qi-biao(College of Light Chemistry and Food Science, South China Univ. of Tech., Guangzhou 510640, Guangdong, China);Mensuration of Chitinase-Producing Abilities of Strains Isolated From Digestion Guts and Farming Water of Haliotis Diversicolor Supertexta[J];Journal of South China University of Technology(Natural Science);2005-03
10 WANG Shun-chun,SHI Song-shan,WENG Ying-qi,WANG Zheng-tao,HU Zhi-bi (Institute of Chinese Materia Medica,Shanghai University of T.C.M.,Shanghai 201203,China);Studies on the structural features and anticoagulant activity of the polysaccharide from Aeodes orbitosa[J];Chinese Journal of Marine Drugs;2007-04
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
2 Ji Yubin, Li Wenju, Gu Chunshan (Department of Pharmacology ,Heilongjiang Commercial College, Harbin 150067);AN EXPERIMENTAL STUDY OF THE ANTICANCER EFFECT OF POLYSACHARIDES MIXTURE[J];Chinese Journal of Marine Drugs;1994-03
3 Li Taiwu Su Xiurong Ding Mingjing (Department of Biology of Liaoning Normal University,Dalian 116022);THE DETERMINATION OF SOME NUTRITIONAL ELEMENTS IN ABALONE HALIOTIS DISCUS HANNAI INO[J];Chinese Journal of Marine Drugs;1995-01
4 Hu Shuigen Wang Yun Zhu Guoping,et al.. (The Naval Pharmaceutical Science Center, 411 Naval Hospital,Shanghai 200081);STUDIES ON ANTITUMOR EFFECTIVE CONSTITUENT OF ANODONTA WOODIANA——Ⅱ SEPARATION AND PURIFICATION OF HB - I PROTEOGLY- CAN[J];Chinese Journal of Marine Drugs;1997-02
5 Zhang Qinfen ,PengJu ,Li Chunhou (South China Sea Fisheries Institute ,CAFS,Guangzhou 510300);PRELIMINARY STUDIES ON THE EXTRACTION AND THE ANTITUMOR ACTIVITY OF RIBONUCLEIC ACID ( RNA ) FROM PINCTADA MARTENSII AND PINNA PECTINATA[J];Chinese Journal of Marine Drugs;1998-02
7 WANG Qun,Lü Chang long,Lü Chao, et al (Department of Immunology,China Medical University,Shenyang 110001);Study on the induction of IFN γ and LAK cells activity in mice stimulated with sepia[J];Chinese Journal of Marine Drugs;2001-01
8 HE Sheng, XIE Guang-lin, HE Ming-chang(Department of Preclinical medicine ,China medical university , shenyang, 110001, China);Studies of sepia influence on NK cells activity and effect on in- hibition tumor in mice[J];Chinese Journal of Marine Drugs;2002-05
9 Qing Kui; Wang Qifeng;et al.;Experimental Study on Anti-stress Action of Guipi Decoction(Rhizoma Atractylodis Macrocephalae Poria, etc,)on Mice[J];CHINESE TRADITIONAL PATENT MEDICINE;1996-12
10 Guo Guohua; Lu Yaobang; Jiang Maoheug; et al ( Hunan College of TCM, Changsha);Effects of Compatibility Between Ginseng (Panax ginseng) and Trogopterus Dung of Complextoothed Flying Squirrel (Trogopterus xanthipes) Decoction On Immune Functions in Immunosuppressed Mice[J];Chinese Traditional and Herbal Drugs;1994-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved