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《Journal of Dali University》 2006-06
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A Study on Pharmacological Effects of Seselopsis on Mice

HUANG Bing,SUN Yan-lin,ZHANG Bu-fen et al(Undergraduates of Pharmacy,2000 Grade,Faculty of Pharmacy,Dali University,Dali,Yunnan 671000,China) Tutor: DU Yi-ming,FANG Chun-sheng,LIU Guang-ming(Faculty of Pharmacy,Dali University,Dali,Yunnan 671000,China)  
Objective: To study the effect of anti-fatigue,anti-anoxia and anti-high-temperature of seselopsis(vicatia thibetica de Boissl) on mice.Methods: ① By mice's swimming test,after seselopsis administration of the extract of vicatia thibetica de Boissl,3.3,6.6,13.4g.kg-1.d-1,qd×7d,ig;extract of ginseng 2.0g.kg-1.d-1 gd×7d,ig;as a control group,recorded the living time of every group and compared it with the control group.② By anti-anoxia test and heat-resistant test,after seselopsis administration of the extract of vicatia thibetica de Boissl,6.6g.kg-1.d-1,qd×5d,ig;extract of ginseng 2.0g.kg-1.d-1 gd×5d,ig,as a control group,the living time of every group were recorded and compared it with the control group.Results: The results showed that extract of seselopsis had obvious effects on improving mice's physical strength,abilities of anti-anoxia and heat-resistant.Compared with the saline control group,the living time of the mice seselopsis taken was much longer(P0.01),and it is no difference between seselopsis groups and ginseng group.Conclusion: The extractive of seselopsis has anti-fatigue effect,anti-anoxia effect and anti-high-temperature effect on mice.
【Fund】: 大理学院大学生科研项目(2004D×34/2005D×31)
【CateGory Index】: R285
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