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《Journal of Dalian Medical University》 2002-01
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The effects of Yi Zhi Chong Ji on treatment of dysmnesia in mice

DAI Su-fang 1,GAO Xi 2,XU Hong 1 (1.Experimental Room of Functionology,Dalian Medical University,Dalian 116027,China; 2.Department of Physiology)  
Objective:To observe the effects of Yi Zhi Chong Ji(YZCJ) on improving learning and memory in mice.Methods:Two kinds of models of dysmnesia were respectively established by injection of scopolamine (0.5 mg·kg -1 .ip) and repeated cerebral ischemia-reperfusion in mice .Influences of YZCJ on the dysmnesia were studied by the step-down test, and the results of learning and memory results were recorded.Results:The number of error in Step-down test was significantly fewer, and the cumulated stimulating time was obviously shorter in the YZCJ group than in the other model groups.Conclusion:The above results suggest that YZCJ be used to treat dysmnesia by both injection of scopolamine and repeated cerebral ischemia-reperfusion.
【CateGory Index】: R285.5
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