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《Journal of Dalian Medical University》 2003-02
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Small-bore catheter drainage and bi-platin intraplueral chemotherapy in treatment of patients with malignant pleural effusion

LIU Su-qin, ZHOU Tao, SUN Liang-xin (Department of Oncology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China)  
To evaluate the clinical effectiveness of small-bore catheter drainage and intrapleural chemotherapy using Carboplatin plus Cisplatin in the patients with malignant plueral effusion. Thirty-six patients with malignant plueral effusion were inserted into the pleural space using 16 F small-bore catheters and connected to a closed drainage bag and received Carboplatin 150 mg/m 2·wk plus Cisplatin 40 mg/m 2·wk for 3 times. The response rate is 88.9 %, CR 23 cases, PR 9 cases and NC 3 cases, and the side effect is mild. [Conclusions] Using a small-bore catheter accompanied by bi-platin intraplueral chemotherapy is effective in the treatment of malignant plueral effusion.
【CateGory Index】: R730.5
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