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《Journal of Dalian Medical University》 2005-06
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Anti-tumour activity of concentrated elemene injection in vitro

DOU Yu-qin1, LIU Yu-xin1, YAN Hui-fang2, LU Hong-qi2 (1. Dalian Institute of Medical and Pharmaceutical Sciences, Dalian 116013, China; 2. Laboratory of Pharmacology, Shanghai Institute of Pharmaceutical Industry,Shanghai 200437, China)  
[Objective] To study the inhibitory effect of concentrated elemene injection on cancer cells in vatro. [Method]Five cell lines of SHG-44, LAX, HL-60, QGY and MGC. The concen the elemene injection with concentrativen of 2%, then cell proliferation inhibitory of concentrated elemene injection by MTT live cell staining method.[Results] Cell proliferation inhibitory rates of SHG-44, LAX, HL-60, QGY and MGC, the IC_ 50 were 56.07~60.47 μg/mL,88.76~92.80 μg/mL,39.37~40.14 μg/mL,90.26~100.82 μg/mL and 61.29~83.64 μg/mL respectively. [Conclusion] Concentrated elemene injection could inhibit proliferation of some tumor cells in vatro.
【CateGory Index】: R73-36
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