Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Dalian Medical University》 2007-03
Add to Favorite Get Latest Update

Dynamic experiment study on anti-tumor immunity with SQ (shenqi) compound recipe

LI Qing,FAN Xiao-lei(Department of Medical Microbiology,Dalian Medical University,Dalian 116027,China)  
[Objective] On these bases,this experiment engaged in the dynamic study on anti-tumor immunity with SQ in order to discover the dynamic modulation on the immune system with SQ and the dynamic changes at immune function in mouse with tumor.[Method] All mice were implanted with tumor,3groups were NS control group,3 groups were CY(cyclophsphamide)treatment group.3 groups were SQ treatment group.NS group and SQ group were given NS and SQ decoction respectively by mouth.CY group was injected intraperitoneally with CY.weigh the tumors and fix then.mature NK/Mφactivity and serum IL-12,TNF-α.[Results] SQ could prolong the life span.suppress the growth of mice bearing tumors.Kill tumors rate of SQ treatment group gets 65.68%,that of CY group is 45.76%,difference with that of NS group(P0.05).SQ could enhance the functions of immune system,it could increase NK/Mφactivities in mice bearing tumors.After the first day of stopping drug,SQ treatment group inculde NK/MΦ increase(55.78±2.23)%/(57.23±1.37)% more than NS group(36.51±1.94)%/(38.57±1.15)%,after 5 d/9 d,they maintain(47.43±1.06)/(47.67±1.01)(P0.05).SQ could activate IL-12 and TNF-α.[Conclusion] SQ had significant anti-tumor effect in vivo.
【Fund】: 辽宁省自然科学基金资助课题(00225003)
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 4 Hits
1 ;Experimental study on anti-tumor effect with Shenqi compound recipe[J];Immunological Journal;2003-04
2 LI Hong zhe, FAN Xiao lei, LI Qing Department of Medical Microbiology, Dalian Medical University, Dalian 116027, China;Effects of Shenqi compound recipe on cell cycle and apoptosis of ascites inducible hepatocarcinoma cell line H22[J];Journal of Cellular and Molecular Immunology;2003-04
3 Medical College of Chinese People's Armed Police Forces (Tianjin 300162) Chen Xiaoyi, Xu Ruicheng, Chen Li Tianjin Institute of Pharmaceutical Research Qian Jin;Studies on the Cytotoxicity of Bufalin on Human Gastric Cancer Cell MGc-803 in vitro[J];Chinese Traditional and Herbal Drugs;2000-12
4 LI Hong Zhe,FAN Xiao Lei,ZHANG Li.Dalian Medical University Department of medical Micrbiology,Dalian 116027,China;Experimental study on anti-tumor effect with Shenqi compound recipe[J];Chinese Journal of Immunology;2003-06
Chinese Journal Full-text Database 10 Hits
1 WANG Jin, YIN Jun-qiang, SHEN Jing-nan, JIA Qiang, HUANG Gang, JIN Song, ZOU Chang-ye Department of Musculoskeletal Oncology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China;In vitro screening of 32 traditional Chinese herbal extracts against U_2OS human osteosarcoma cells[J];Journal of Southern Medical University;2006-09
2 ZHANG Xiao-mei 1a ,LUN Yong-zhi 1a ,WANG Ren-jun 1b ,HUANG Min 2,CAO Li-li 1a n;Immune mechanisms of the antitumor effects of F_3 preparation from Astragalus membranaceus[J];Immunological Journal;2005-01
3 Sun Ning,Xu Yufang,Liu Fenxia Henan College of Chinese Medicine,Zhengzhou,Henan,China 450008;The Effect on Morphology of Oxymatrine On Hunman Gastric Cancer MGC-803 Cell line Transplantation Tumor[J];China Journal of Chinese Medicine;2010-06
4 LIANG Jun-cai,ZHANG Xiu-hua,YOU Si-hong,HE Wei,MIAO Lin(Institute of Digestive Endoscopy and Medical Center for Digestive Diseases,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011,Jiangsu,China);Effects of bufalin on the proliferation and expressions of cyclin E and P27 in changliocarcinoma cell line QBC939[J];Journal of Medical Postgraduates;2010-11
5 ZHANG Jia-mei(Shandong Pharmaceutical Industry Designing Institute,Ji'nan 250013);Research advance on anticancer effect of Bufonis[J];Qilu Pharmaceutical Affairs;2008-07
6 QIAO Li,DUAN Wen-juan,YAO Yao,CHEN Huan,LIU Tao,PEI Yue-hu(School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China);Isolation and identification of bufadienolides from traditional Chinese drug Venenum Bufonis[J];Journal of Shenyang Pharmaceutical University;2007-10
7 ;Progress on pharmacology and mechanism of Chan Su with the active components[J];Acta Academiae Medicinae Cpapf;2003-05
8 QI Gang, ZHANG Li, HE Wen-tong, CHEN Xiao-yi, HU Wen-liang (Department of Central Laboratory, Medicial College of Chinese People's Armed Police Force, Tianjin 300162, China);The study on acute-toxicity of Bufalin[J];Acta Academiae Medicinae Cpapf;2004-01
9 XU Rui cheng 1, CHEN Xiao yi 1, CHEN Li 1, HU Wen liang 1, QIAN Jin 2 (1 Medical College of Chinese People's Armed Police Forces, Tianjin 300162, China; 2. Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China);HL-60 cell differentiation induced by bufalin and its relative gene expression[J];Chinese Traditional and Herbal Drugs;2002-02
10 Guo Jiangong1, Wang Chuyi2, HasiSurong2, Jirimutu1 (1.Key Lab of Dairy Biotechnology and Bioengineer, Education Ministry of P.R China College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018; 2.College of Animal Science and Medicine, Inner Mongolia Agricultural University, Hohhot, 010018);Effects of Naturally Fermented Bactrian Camel’s Milk on H_(22) Cells of Mice Ascites Carcinoma[J];China Dairy Cattle;2009-01
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 WANG Zhao-tai, DONG Guang-long, WANG Wei-zhong Department of Gastrointestinal Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China;The effects of Kang-Lai-Te on apoptosis and proliferation of advanced gastric cancer cells and T-cell subset in gastric cancer patients[J];Journal of Cellular and Molecular Immunology;2002-05
2 Tian Pu-xun;Nan Xun-yi; Li Xu; et al.(Department of Urology, The First Affiliated Hospital, Xian Medical University,Xian 710061);An experimental study of chansu liposome on extraculture cell of human bladder cancer BIU-87[J];CHINESE JOURNAL OF VROLOGY;1994-06
3 SHAN Bao en, ZHANG Jin yan, DU Xiao na, et al The Research Center 4th Hospital, Hebei Medical University, Shijiazhuang (050011);Immunomodulatory Activity and Anti-Tumor Activity of Oldenlandia Diffusa in vitro[J];Chinese Journal of Integrated Traditional and Western Medicine;2001-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved