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《Journal of Dalian Medical University》 2008-04
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Effect of compound surfactants on O/W microemulsion region

ZHAO Shan,FAN Qing(Department of Pharmacy,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China)  
[Objective] To study the effect of compound surfactants on the O/W microemulsion(ME) region,which was guidance for selection the formulation of ME.[Methods] Phospholipid(PC) and Poloxamers 188(F68) were used as compoundsurfactants,glycerol as cosurfactant,ethyl oleate as oil phase.Prepare the pseud-triangularphase diagrams with different ratio of surfactant/cosurfactant(Km) and F68/PC.Whilefor the PC,glycerol and ethyl oleate system with the same condition.Then,the correspondingarea of O/W ME in both system were compared.The effect of compound surfactantson the O/W ME region was investigated.[Results]The micromulsion region of compound surfactants system was larger than the single surfactant system.In the scope of this study,thearea of ME region was decrease when the Km1 or Km1,while the area of ME was increase with the increase of the ratio of F68.[Conclusions]The microemulsion region of compound surfactants system is more larger than the single surfactant system.The afflication of compound surfactants is a feasible method with guiding significance for the selection of ME formulation.
【Fund】: 辽宁省科技基金(2005225012-9)
【CateGory Index】: R94
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【References】
Chinese Journal Full-text Database 3 Hits
1 LI Zi-wei;HUANG Hua;QIN Yao;XIAO Kun-quan;LUO Wei-zao;YANG Yong;GU Dan-dan;Department of Pharmaceutics,Chongqing Medical University;Taiji Group;Chongqing Institute of Traditional Chinese Medicine,Key Laboratory of Natural Resources of Chinese Medicinal Materials of Chongqing;Department of Medicinal Chemistry,Chengdu Chinese Medicine University;;Preparation of Sodium Aescinat Micro-emulsion for Injection[J];Journal of Sichuan University(Medical Science Edition);2014-01
2 Huang Juanping,Li Sufang,Li Jiao,Kang Meng,Han Tianheng(State Key Laboratory of Chemo/Biosensing and Chemometrics,College of Chemistry and Chemical Engineering,Hunan University,Changsha,410082,China);Study on Preparation of Waterborne Epoxy Emulsion with Composite Emulsifier and Its Film Properties[J];Paint & Coatings Industry;2013-06
3 HUANG Juanping;LI Sufang;LI Jiao;KANG Meng;WANG Congcong;LIU Tingting;State Key Laboratory of Chemo/Biosensing and Chemometrics,College of Chemistry and Chemical Engineering,Hunan University;;Synthesis and Properties of Waterborne Epoxy Composite Emulsifier[J];Chinese Journal of Applied Chemistry;2014-03
【Citations】
Chinese Journal Full-text Database 5 Hits
1 XIANG Dong,ZHANG Li, YE Li- min,ZHANG Zhi - rong ( West China School of Pharmacy, Sichuan University, Chengdu 610041, China);Preparation of Norcatharidin microemulsion and its quality evaiuatikm[J];West China Journal of Pharmaceutical Sciences;2004-02
2 WT4”,5BZ]LU Bin, ZHANG Zheng quan (School of Pharmacy, West China University of Medical Sciences, Chengdu 610041, China) [WT4”,5HZ];APPLICATION OF TRIANGULAR PHASE DIAGRAMS TO INVESTIGATE THE FORMULATION CONDITIONS OF PHARMACEUTICAL MICROEMULSIONS[J];Acta Pharmaceutica Sinica;2001-01
3 PAN Guoliang,JIA Xiaobin(Jiangsu Provincial Academy of TCM,Nanjing210028,China) PAN Guoliang,JIA Xiaobin,WEi Huihua,WANG Yong(Jiangsu University,Zhenjiang212013,China);Comparison among Several Preparation Methods for Pseudo-ternary Phase Diagrams of Pharmaceutical Microemulsions[J];China Pharmacy;2006-01
4 LIAN Yun-Fei, LI Juan*, PING Qi-Neng, YAN Fei(Dept. of Pharmaceutics,China Pharmaceutical University, Nanjing 210009);Preparation and Transdermal Absorption of Indomethacin Microemulsion[J];Chinese Journal of Pharmaceuticals;2005-03
5 WANG Yang, WU Wei*, QUE Li (Dept. of Pharmaceuticals, School of Pharmacy, Fudan University, Shanghai 200032);Application of Pseudo-ternary Phase Diagrams for Oil-Tween-alcohol-water System in Self-microemulsifying Drug Delivery System[J];Chinese Journal of Pharmaceuticals;2005-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 QIAN Wei et al(School of Biology and Food Engineering,Dalian Industry University,Dalian,Liaoning 116034);Preparation of Nano-plant Sterol Ester by Oil-in-water Micro Emulsion Method[J];Journal of Anhui Agricultural Sciences;2009-08
2 FU Xiu-juan et al (School of Pharmacy,Luzhou Medical College,Luzhou,Sichuan 646000);Optimization of Inclusion Technology for 6-Gingerol in RHIZOMA ZINGIBERIS[J];Journal of Anhui Agricultural Sciences;2011-06
3 HUA Xiao et al(School of Food Science and Technology,Jiangnan University,Wuxi,Jiangsu 214122);Preparation of Snack Food Fruit-vegetable Chewing Tablets[J];Journal of Anhui Agricultural Sciences;2011-30
4 TANG Li Qin, LIU Sheng, CHEN Li Ming, CHEN Xiang Qing, TIAN Li (Anhui Provincial Hospital, Hefei 230001);Selection of excipient on compound folium sennae pellets[J];Anhui Medical and Pharmaceutical Journal;2002-04
5 HU Shi Lin (Dept of Pharmacy, Anhui Provincial Hospital, Hefei 230001);The improvement and quality control on furacilin solution prescription[J];Anhui Medical and Pharmaceutical Journal;2003-02
6 LI Yuan fu,XU Ming (Yijishan Hospital Wannan Medical College,Wuhu 24001,China);Examination of the quality of purified water made by twice reverse osmosis[J];Anhui Medical and Pharmaceutical Journal;2004-04
7 XIE Dong-mei,LIU Cong-bin (School of Pharmacy,Anhui College of TCM,Hefei 230031,China);Preparation of free-sugar suspension granule of guizhifuling[J];Anhui Medical and Pharmaceutical Journal;2005-05
8 WAN Mao-lin,SUN Yu-liang,ZHANG Qun-wei(The School of Materia Madica of Anhui College of Traditional Chinese Medicine,Hefei Anhui,230038);Preparation of dispersible propranolol hydrochloride tablets[J];Anhui Medical and Pharmaceutical Journal;2009-07
9 QI Xue-ping1,GUI Shuang-ying1,2,3,LIU Peng1,CHENG Bing1,PENG Dai-yin2,3 (1.Anhui Traditional Chinese Medicine,2.Anhui Engineering Research Center of Modernized Chinese Material Pharmacy Teaching and Research,3.Research & Development Innovative Team of Modernized Chinese Material of Anhui Province Hefei 230031);Preparation technology of the tetrandrine self-microemulsifying system[J];Anhui Medical and Pharmaceutical Journal;2010-04
10 Yu Xiujuan Yu Hongjie Bao Changjin1 (Hospital for Mother and Child Health Care of Xing'an League,Wulanhaote, 137400, 1Xing'an League Institute for Drug Control, Wulanhaote, 137400);Preparation and Quality Control of Paracetamol,Caffein,Chlorphenamine Maleate and Methylephedrine Hydrochloride Capsules[J];Journal of North Pharmacy;2006-03
China Proceedings of conference Full-text Database 10 Hits
1 ZHAO Li-Jie 1,FENG Yi 1,XU De-sheng 2,RUAN Ke-Feng 1,FU Xiao-Ju (1.Engineering Research Center of Modern Preparation Technology of TCM,Ministry of Education,Shanghai University of TCM,Shanghai 201203,China;2.Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China);Effect of Physical Characteristics on Hygroscopicity of Chinese Traditional Medicine Raw Materials[A];[C];2011
2 WANG Zhaohong (Guangyuan Food and Drug inspection office,Guangyuan 628000,Sichuan,China);Analysis of Hydrochloric Acid Berbamine Sugarcoating Piecespilt and Countermeasures to the Spilt[A];[C];2009
3 TIAN Lei~1,YANG Da-kai~2,CHEN Wu~2 1 Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing 210029,China 2 Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China;Study of Permeation Enhancers of shangkexiaoyan Cataplasm[A];[C];2010
4 ;SLB脂质纳米粒小鼠体内外相关性研究[A];[C];2008
5 Jian Xiaona~1 HU Ming~2 Jiang Xuehua~(*2) (1.Chengdu Pharmaceutical Co.,Diao Group;2.West China School of Pharmacy,Sichuan University);The study of management about approed oral solid chemical drug's formulation and manufacture process improvement[A];[C];2009
6 LIU Ji-Yong, HAN Ying, YANG Ming, ZHU Quan-Gang, HU Jin-Hong* (Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China);Preparation of Paeonol Microemulsion Gel and transdermal Characterization in vitro[A];[C];2009
7 WU Min~1,YAN Hui-yu~1,GUO Qiu-shi~1,LIU Hong-jian~1,DING Zhi-ying~(1*) (School of Pharmaceutical Sciences,Jilin University,Changchun 130021,China);Preparation and quality evaluation of Andrographolide microemulsion[A];[C];2010
8 LIU Ji-Yong,HAN Ying,YANG Ming,ZHU Quan-Gang,HU Jin-Hong (Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China);Preparation of Paeonol Microemulsion Gel and transdermal Characterization in vitro[A];[C];2010
9 CAO Fa-hao OUYANG Wu-qing (College of Annimal Science and Technology,Northwest A&F University,Yangling 712100,Shanxi;China);Study on the Preparation and in Vitro Antibacterial Activity of Furacillin Nanoemulsion[A];[C];2008
10 SUN Jiang-cai OUYANG Wu-qing XU Li-geng YANG Xue-feng LIYun-rang (College of Animal Medcine,Northwest A&F University,Yangling,Shanxi 712100;China);The Preparation and Antibacterial Activity in Vitro of Furacilin-Tinidazole Combination Nanoemulsion[A];[C];2008
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 GAN Zhi-ping,GUAN Jian-guo,WANG Zhen-jie(State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology,Wuhan 430070,China);Effects of the Polymerization Conditions on the Structure of P(St-co-AA)Latexes[J];Micronanoelectronic Technology;2005-07
2 HU Hao~(1,2),LIU Yong-ru~2,TU Wei-ping~1,ZHANG Li-ping~2 (1.Mobile Post-doctoral Stations,School of Chemistry and Chemical Engineering,South China University of Technology, Guangzhou,Guangdong 510640,China;2.R&D Center,Guangzhou Liby Enterprise Group Co.Ltd,Guangzhou,Guangdong 510170,China);Study of particle size change during AA-MA copolymerization in aqueous solution[J];China Surfactant Detergent & Cosmetics;2010-06
3 YI Xiang,YANG Hui-qiong,XIAO Xin,HUANG Jian-bing(Department of Chemistry and Chemical Engineering,Hunan Institute of Engineering,Xiangtan 411104,China);Development of a Rust-Conversion Fluid for Steel[J];Materials Protection;2007-05
4 XU Rui-ting,ZHANG Yu-cang ZHANG Wen-ming Institute of Resources Recycling,Dalian Polytechnic University,Dalian 116034,China;Preparation of straw-based epoxy resin emulsion and its coating property[J];Electroplating & Finishing;2012-03
5 JIA Yun~(1),LIU Huo-an~(1,2),DAI Chuan-yun~(2)(1.College of Chemistry and Bioengineering,Chongqing Polytechnic College,Chongqing 400050,China;2.College of Bioengineering,Chongqing University,Chongqing 400030,China);Study Progress of Controlled-delivery System on Vaccine[J];Journal of Chongqing University(Natural Science Edition);2006-02
6 Wang Guojian,Liu Yang,Wang Lijuan(School of Materials Science and Engineering,Tongji University,Shanghai 200092,China);Study on the Synthesis and Properties of Water Dispersed Alkyds Resin[J];Guangdong Chemical Industry;2007-01
7 Luo Guanghua,Zheng Dianmo,Li Guangmei(School of Environment Science and Engineering,Nanchang University,Nanchang 330029,China);Choice of Emulsifier for O/W Emulsion[J];Guangdong Chemical Industry;2008-11
8 ZHU Yan, YANG Zhen-Zhong, ZHAO De-Lu (Polymer Physics Laboratory, Center for Molecular Science, Institute of Chemistry, The Chinese Academy of Sciences, Beijing 100080, China);Effects of the Hydrophilic Composition PEG Content in the Emulsifier Molecules on Phase Inversion Process[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;2000-02
9 LI Shan-Jun, ZHANG Shu-Yong, LUO Xiao-Wen, DING Yi-Fu, ZHOU Wei-Fang ( Department of Macromolecular Science, the Key Laboratory of Molecular Engineering of Polymers, State Educational Ministry; Department of Chemistry, Fudan University, Shanghai 200433,;Comparison of the Effects of Acetoxy and Hydroxy Groups on the Water Uptake into the Cured Epoxy Resin[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;2000-05
10 WANG Hai\|Bo, LIU De\|Shan  (Department of Chemical Engineering and School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China);Investigation of the Factors Influencing the Process of Emulsification United Effect of cmc_O and cmc_W[J];Chemical Research In Chinese Universities;2002-09
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 LIU Hong-qing,LI Ying-bo Chinese Academy of Medical Sciences,Peking Union Medical College,Institute of Medical Biology,Kunming 650118,Yunnan Province,China;Progress in research on nanoemulsion adjuvant in influenza vaccine[J];Chinese Journal of Biologicals;2013-08
2 WU Kangyu HUANG Zhihui CHEN Turong XIONG Ying▲ The Affiliated Orthopaedics and Traumatology Hospital of Traditional Chinese Medicine University of Guangzhou,Guangdong Province,Guangzhou 510240,China;Study on preparation and stability of emodin microemulsion[J];China Medical Herald;2013-24
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 CHU Ai wu 1* ,CUI Yue hong 2,LIU Wen bo 3,JIANG Shao jun 3 (1 Department of Pharmacy,the Affiliated Hospital of Binzhou Medical College;2 Hospital of Binzhou Industrial School; 3 Electron Microscopy Laboratory,Binzhou Medical College,Shandon;Mechanism of oleic acid-induced percutaneous penetration enhancement: an ultrastructural study[J];Journal of Chinese Electron Microscopy Society;2002-02
2 WU Shun-qin 1, LI San-ming 1, ZHAO Guo-bin 2 (1. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China; 2. The Institute for Drug Control of Jilin Province, Changchun 130062, China);Microemulsions and their application to pharmaceutics[J];Journal of Shenyang Pharmaceutical University;2003-05
3 Tian Wei, Yang Yahui, Wang Maoyi (Department of pharmacy,First Affiliated Hospital);THE EFFCT OF AZONE ON PENETRATION OF INDOMETHACIN[J];Journal of Xi'an Jiaotong University(Medical Sciences);1992-04
4 Lu Qiuhong and Chen Zhaokun (Hainan Institute for Drug Control,Haikou 570102);An Improved Method for the Determination of Cantharidin Cream[J];CHINESE JOURNAL OF PHARMACEUTICAL ANALYSIS;2000-05
5 WT4”,5BZ]LU Bin, ZHANG Zheng quan (School of Pharmacy, West China University of Medical Sciences, Chengdu 610041, China) [WT4”,5HZ];APPLICATION OF TRIANGULAR PHASE DIAGRAMS TO INVESTIGATE THE FORMULATION CONDITIONS OF PHARMACEUTICAL MICROEMULSIONS[J];Acta Pharmaceutica Sinica;2001-01
6 Tang Ganghua (Tang GH), Wang Shizhen (Wang SZ), Wu Shuqin (Wu SQ), et al (Peking Uion Medical College Hospital, Chinese Academy of Medical Sciences, Peking Uion Medical College, Beijing 100730);Organic synthesis of perlolyrine[J];CHINESE PHARMACEUTICAL JOURNAL;1998-08
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