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Discovery and application of green fluorescent protein

ZHANG Xin-sheng1,LIU Xiao-yu1,REN Shuang-yi2(1.Seven-Year Program of Clinical Medicine,Dalian Medical University,Dalian 116044,China;2.Department of General Surgery,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China)  
Green fluorescent protein(GFP) is a kind of bioluminescent protein that can emission visible green light when it is excited by ultraviolet or blue light.Because of its illuminant characteristic,the applied perspective of GFP is extensive in scientific research,biology,medicine and the other fields.GFP's high resolution crystal structure provides a opportunity to understand and study protein structure and spectroscopy function.So it has become an idea marker for monitoring gene expression and protein localization in integral cell and tissue.Discovery and applied perspective of GFP will be reviewed in this article.
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