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The changes of red blood cell and lynphoid organs LPO and SOD levels of the hosts bearlng highly and lowmetastatic tumor line

Xu Yuefei,et al.(Dept.of Biochemistry,Dalian Medical University)  
In this paper,we use Hca-F25/CL-16A3 and A2 to attack 615 mice and observed the influence of tumor lines on the superoxidation and antioxidation of RBC and lymphoid organs.The results showed hat SOD/LPO ratio of tumor-bearing groups is obviously lower than that of the control group.The ratio of the group bearing highly metastatic line is much lower than that of the low-metastatic group.However,the ratio change extent is different.This may be related to different immunogenicity of tumor lines.These results suggested that the occuring and development of tumors are closely related to the increase of peroxidation and the decrease of antioxidative activities.It is worth to do further investigation.
【CateGory Index】: R735.7
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