Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Southeast University (Natural Science Edition)》 2003-04
Add to Favorite Get Latest Update

Study on binding characteristics of (S)-naproxen imprinted polymer and performance of its complexes during preparation

Li Ping Rong Fei Xie Yibing Zhu Xinle Yuan Chunwei ( 1Department of Biomedical Science and Medical Engineering, Southeast University, Nanjing 210096, China) ( 2Department of Bioengineering, Beijing University of Aeronautics and Astronautics, Beijng 100083, China)  
A molecularly imprinted polymer (MIP) was synthesized as the highly chiral selective materials for (S)-naproxen with acrylamide as functional monomers. UV (ultra-violet) studies showed that the template (S)-naproxen and functional monomer acrylamide formed complexes before polymerization and Hyperchem was used to simulate the structures of complexes. The binding capacity of MIP to (S)-naproxen is higher than that of its enantiomer and the chiral separation factor α is 1 87. Scatchard analysis suggests the MIP recognizing (S)-naproxen with two classes of binding sites. The calculated dissociation constant K d,1 and apparent maximum number Q max,1 of binding sites with high affinity are 28 0 μmol/L and 52 94 μmol/g respectively, while K d,2 and Q max,2 of binding sites with low affinity are 0 489 mmol/L and 0 122 mmol/g.
【Fund】: 高校博士学科点专项科研基金资助项目( 2 0 0 10 2 860 0 6);; 江苏省自然科学基金资助项目(BK2 0 0 10 15 )
【CateGory Index】: O631
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 4 Hits
1 JIAO Feipeng HUANG Kelong YU Jingang PENG Xiahui ZHAO Xuehui NING Fengrong (College of Chemistry and Chemical Engineering,Central South University,Changsha 410083);Study on Process of Thermodynamics for Chiral Separation of Naproxen in Molecular Imprinting[J];Materials Review;2005-08
2 WANG Xue-jun,XU Zhen-liang~*,BING Nai-ci(Chemical Engineering Research Center,East China University of Science and Technology,Shanghai 200237,China);Concept of Imprinting Efficiency and Recent Progress of Molecular Imprinting[J];Chemical World;2007-04
3 Zheng Haiyan Ma Fen Shao Wei Fang Lei Wang Cheli (Department of Chemical Engineering,Jiangsu Polytechnic university,Changzhou,213164,Jiangsu,China,;Molecular simulation for preparation of molecularly imprinted polymers of salicylic acid by using different functional monomers[J];Computers and Applied Chemistry;2008-12
4 ZHU Xiu-fang, HOU Neng-bang, WANG Guo-song, CAO Qiu-e, DING Zhong-tao(Department of Chemistry, Yunnan University, Kunming 650091, China);Rapid Screening for Non-convalented Molecular Imprinted Systems[J];Yunnan Chemical Technology;2005-01
Chinese Journal Full-text Database 10 Hits
1 Wei Xiang(DepartmentofExperimentandHandlingofMaterialsofAnhuiUniversity,Hefei230039);Analysis of Permethrin by HPLC[J];Anhui Chemical Industry;2002-04
2 TANG Shu-yuan, LI Chuan-yi, ZHANG Peng-cheng, XIE Lin, LI Qi-lin, LUO Lin (Agro-Environment Protecting and Monitoring Station of Chongqing City, Chongqing 400020, China);INVESTIGATION ON HEAVY METAL POLLUTION TO VEGETABLES IN CHONGQING[J];Journal of Safety and Environment;2003-06
3 SU Hai jia HE Xiao jin TAN Tian wei (College of Chemical Engineering, Beijing University of Chemical Technology, Beijing 100029, China);Adsorption properties of heavy metal ions from wastewater with chitosan-chelated bead[J];Journal of Beijing University of Chemical Technology;2003-02
4 BAI Hong-ying~1, JIA Meng-qiu~1 , WU Wei~2 ,WANG Jin-ling~1(1.School of Materials Science and Engineering,Beijing University of Chemical Technology,Beijing 100029,China; 2.Research Center of the Ministry of Education for High Grarity Engineering and Technology,Beijing University of Chemical Technology,Beijing 100029,China);In-situ Modification of NM SiO_2 and its Application in the Heat-Resisting Coating[J];Surface Technology;2003-06
5 CHEN Yun-hui~1,LI Wen-fang~1,DU Jun~1,CHEN Dong-chu~1, WU Xi-kun~2,LIANG Yi-qing~2(1.School of Mechanical Engineering,South China University of Technology,Guangzhou 510640,China;2.Guangdong Xingfa Group Co.,Ltd,Foshan 528000,China);Composite Modification New-style Surface Active Agent for Nano-sized SiO_2[J];Surface Technology;2006-05
6 LIU Bolin YAN Jinghui HUI Boran (college of materials and chemical engineering, changchun university of science and technology, changchun 130022);Study on Modified Bentonite in Absorbing the heavy metal ions[J];Journal of Changchun Institute of Optics and Fine Mechanics;2005-01
7 XU Lei, HAN Jinghong, LIANG Weiguo,ZHANG HongElectronics,Chinese Academy of Sciences,Beijing 100080,China);Application of light-addressable potentiometric sensor in organophosphorus insecticide determination[J];Journal of Transducer Technology;2003-10
8 Shen Weiren, He Fei, Zhao Wenkuan, Fang Youling (College of Chemistry, Wuhan University, Wuhan 430072);PREPARATION OF NANOCRYSTAL TITANIA BY SUPERCRITICAL DRYING[J];CHINESE JOURNAL OF CATALYSIS;1999-03
9 PENG Rong hua, CHEN Li juan, LI Xiao xiang (School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China).;Adsorption of Wastewater Containing Heavy Metal Ions by Modified Fly Ash[J];Materials Protection;2005-01
10 PENG Rong-hua, LI Xiao-xiang (School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China).;Adsorption of Ni 2+ and Cd 2+ Ions by Acid-Modified Bentonite[J];Materials Protection;2006-01
【Secondary References】
Chinese Journal Full-text Database 5 Hits
1 ZHU Qiu-jin1,DAI Jun2,CHENShang-wei2,GU Xiao-hong2,TANG Jian2(1.School of Life Science,Guizhou University,Guiyang550025;2.Testing &Analysis Center,Southern Yangtze U-niversity,Wuxi 214036,Jiangsu);THERMODYNAMICS STUDY OF SEVERAL STEROLS ISOMERS SEPARATION ON TFMAA-co-TIRM MOLECULARLY IMPRINTED POLYMER[J];Guizhou Science;2007-S1
2 WANG Pan,XIONG Wei-de,ZHANG Ying-qing(College of Bioengineering,Hubei University of Technology,Wuhan 430068,China);Advance in the Molecular Imprinting Based Protein Recognition[J];Chemistry & Bioengineering;2008-09
3 Huang Weihong1 Chen Xiaoting1 Xu Wanzhen2 Yan Yongsheng2(1.School of Environment,Jiangsu University,Zhenjiang 212013,China;2.School of Chemistry and Chemical Engineering,Jiangsu University,Zhenjiang 212013,China);Studies on preparation and characteristics of binding and recognition of phenol molecular imprinted polymers[J];Chinese Journal of Environmental Engineering;2011-01
4 LUAN Chonglin1,LI Mingjie1,2,LI Zhongjin2,SU Xiuxia2,JIANG Xiaohua1(1Department of Fine Chemicals & Materials,Shenzhen Polytechnic College,Shenzhen 518055,Guangdong,China; 2 Key laboratory of Auxiliary Chemistry & Technology for Chemical Industry,Ministry of Education, School of Chemistry and Chemical Engineering,Shaanxi University of Science & Technology, Xi'an 710021,Shaanxi,China);Progress of molecularly imprinted electrochemical sensor[J];Chemical Industry and Engineering Progress;2011-02
5 ZHU Qiu-jin1,2,TANG Jian1,2,3,*,DAI Jun3,GU Xiao-hong3,CHEN Shang-wei3 (1.Key Laboratory of Food Science and Safety, Ministry of Education, Southern Yangtze University, Wuxi 214036, China;2.School of Food Science, Southern Yangtze University, Wuxi 214036, China;3.Analysis and Testing Centre, Southern Yangtze University, Wuxi 214036, China);Synthesis and Characterization of Molecularly Imprinted Microspheres as β-estradiol Antibody Binding Mimics[J];Food Science;2006-10
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved