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《ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE》 2000-04
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Evaluation of histamine-releasing activity in the serum of the patients with chronic idiopathic urticaria

SUN Ren-shan, LIU Rong-qing, YIE Qing-yi, DIAO Qing-chun, XIANG Ming-ming, ZHANG Li, HUANG Xiu-ying (Department of dermatology, Southwest Hospital, Third Military Medical University, Chongqing 400038,China)  
Objective To evaluate the histamine-releasing activity in the serum of the patients with chronic idiopathic urticaria (CIU). Methods Skin tests with autologous serum and basophil histamine-release assay (BHRA)were performed. Results The positive rates of skin tests with autologous serum and BHRA were 37.5% and 43.75 respectively. Conclusion Certain patients with ClU exhibited elevated histamine-releasing activity in their serum. This implies unusual activating mechanism of their mast cells and basophils. It may be related to autoimmunity.
【Fund】: 重庆市科学技术委员会院士基金
【CateGory Index】: R758.24
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【References】
Chinese Journal Full-text Database 2 Hits
1 ZHAO Yan-ming, YI Ji-yuan, CAI Li (The Institute of Prevention and Treatment of Dermatosis of Heilongjiang Province, Harbin 150001, China);Significance and Improvement of Plasma Data Detection of Urticaria[J];Heilongjiang Medical Journal;2005-05
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【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LIU Yu mei 1,YE Shao qiong 1,LI Ping 1,JIANG Xiu ying 2 (1 Institute of Dermatology,Guang Zhou 510095 China; 2 Dept.of Dermatology, China Japan Union Hospital,Jilin University) [;Detection and analysis on the specific IgE level in patients with urticaria[J];Journal of Norman Bethune University of Medical Science;2001-03
2 YANG Bin, DIAO Qing-chun, ZHONG Bai yu, et al. (Department of Dermatology, Southwest Hospital, the Third Military Medical University,Chongqing 400038,China);Assay of skin prick test in patients with chronic urticaria in southwest China[J];Chongqing Medical Journal;2002-12
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【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 YAN Jun,LI Tao,HUANG Xiao-zhong.(Department of Dermatology,Maoming People's Hospital,Guangdong 525000,China);Serum Levels of IL-2,IL-4 and TNF-α in Case with Chronic Idiopathic Urticaria[J];Southern China Journal of Dermato-Venereology;2007-03
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