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《Acta Academiae Medicine Militaris Tertiae》 2001-11
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Analysis of short-term therapeutic efficacy of radio-frequency ablation on 14 cases of medium and small hepatocarcinoma

CHEN Min, FAN Lin jun, MA Kuan sheng, HUANG Xiao lan, DONG Jia hong, HE Zheng ping (Institute of Hepatobiliary Surgery of PLA, Southwest Hospital, Third Military Medical University, Chongqing 400038, China)  
Objective To explore the therapeutic efficacy of radio frequency ablation (RFA) in the treatment of medium and small hepatocarcinoma (diameter ≤5 cm). Methods A total of 14 cases of medium and small hepatocarcinoma with 18 foci treated with RFA were analyzed. Peroid and times of treatment and the patients' reactions to RFA were observed, and needle biopsy and images of hepatic foci were recorded before and after RFA. All cases had been followed up for at least 12 to 18 months. Results Eighteen foci of 14 cases had treated with RFA for 1 to 2 times with mean therapeutic peroid of 50 min. The patients' major reaction to RFA included self limited hemorrhage of the wounds, increased transaminase, hyperpyrexia and pain of liver region. Coagulation necrosis and fibrous tissue were found with multi point needle biopsy of every focus in 9 patients. Enlarged hypo attenuation foci were seen on CT scans after RFA, and no obvious hyper attenuation on the contrast enhanced CT scans, the foci became contracting in 3 months. Complete necrosis was seen in 13 cases (93%). All cases survived during the subsequent following up of 12 18 months. Conclusion RFA appears to be an effective, safe, and relatively simple procedure for the treatment of small hepatocarcinoma, and is expected to become one of the principal way of treating medium and small hepatocarcinoma.
【CateGory Index】: R735.7
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