Adsorption and separation properties of AB-8 resin for purifying arctinin
LU Lai-chun1,ZHANG Rong1,ZHOU Shi-wen2,JIANG Xue-wen1 (1 Department of Pharmacy, 2 Base for Drug Clinical Trial,Xinqiao Hospital,Third Military Medical University,Chongqing 400037, China)
Objective To study the separation ability of AB-8 macroporous resin in the purification of arctinin in Fructus arctii. Methods HPLC was used to measure the content of arctinin, and the adsorption performance and the elution parameters were investigated. Results The optimal separation conditions were as follows: the concentration of Arctinin was 5.5 mg/ml with a flow rate of 2 BV/h, and 50% alcohol was used as eluant. The adsorption of Arctinin was 52.08 mg/g, and the elution ratio of arctinin was 93.8%, and the purity of arctinin reached 65.2%. Conclusion AB-8 resin can be used to refine the arctinin in the extraction of Fructus arctii.
【CateGory Index】： R284