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《Acta Academiae Medicinae Militaris Tertiae》 2007-15
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Effect of Fiveleaf Gynostemma Herb on hyperlipoidemia and hemorheological changes in rabbits

TAN Hua-bing(Medical Department,The People's Hospital of Yunyang Medical College,Shiyan 442000,China)  
Objective To study effect of Fiveleaf Gynostemma Herb on hyperlipoidemia and hemorheological changes in rabbits.Methods Forty rabbits were randomly divided as groups A(fed with high fat food plus 5 g/kg Fiveleaf Gynostemma Herb),B(high fat food plus 5 mg/kg simvastatin),C(high fat food),E(standard feedstuff).TG,TC,LDL-C,HDL-C,endothelin-1(ET-1)and hemorheological indexes(blood viscosity,plasma viscosity,erythrocyte aggregation)were checked before experiment and at 9th week after experiment.Ultramicrostructure of endothelial cells was observed.Results TG,TC and LDL-C of groups A,B and C increased gradually.TG,TC,LDL-C of groups A and B were lower than those of group C(P0.05-0.01).TG,HDL-C,LDL-C of group A were higher than those of group B(P0.05-0.01).TC of group B was higher than that of group A(P0.05).ET-1 of groups A,B and C increased gradually(P0.01),that of groups A and B lower than group C(P0.01).Blood viscosity,blood viscosity and erythrocyte aggregation were higher than those before experiment(P0.05-0.01),those of groups A,B higher than group C(P0.05).As compared with group C,endothelial cell injury in groups A and B was lighter,with few lipid droplet vacuoles in cytoplasm,various cell organs and elastic membrane.Conclusion Fiveleaf Gynostemma Herb has interference effect on hyperlipoidemia and hemorheological changes in rabbits fed with high fat food.
【Fund】: 湖北省十堰市科技攻关项目(2005075D)~~
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 1 Hits
1 TENG Li-xin1,LIU Sheng-xue2,HE Zuo-yun1(1Department of Cardiovascular Diseases,Xinqiao Hospital,Third Military Medical University,Chongqing 400037;2Department of Military Toxicology,College of Military Preventive Medicine,Third Military Medical University,Chongqing 400038,China);Effects of hypercholesterolemia on hemorrheology and cTn-I in rats[J];Acta Academiae Medicinae Militaris Tertiae;2009-22
【Citations】
Chinese Journal Full-text Database 3 Hits
1 MA Lingjun,CHEN Qunli,YANG Wubiao,XI Shoumin,WAN Xuedong,TANG Xiaoming,YU Yanni,KANG Jian Department of Biochemistry and Molecular Biology,Medical College, Henan University of Science and Technology,Luoyang 471003;Effect of lycium barbarum polysaccharide against atherosclerosis in rabbits[J];Journal of Zhengzhou University(Science Medical);2005-02
2 CHEN Xin,WANG Lin,YANG Hang-dong, et al . (Department of Cardiology ,Dongfeng Hospital,Yunyang Medical College,Shiyan,Hubei 442000);The Comparison of the effects of Defibrase,Valsartan and Simvastatin on Atherosclerosis in Rabbits Fed with Cholesterol-Rich Diet[J];Journal of Yunyang Medical College;2004-03
3 LI Feng-wen,LIU Xiao-ying,ZHANG Li-shi,LIU Hong,PAN Jing-hua,JIA Xiao-yuan,DING Jia-xin (Institute of Basic Theory, China Academy of Traditional Chinese Medicine,Beijing 100700, China);Effect of Maifukang on Endothelial Function in Rabbits with Hyperlipoidemia[J];China Journal of Basic Medicine In Traditional Chinese Medicine;2003-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SONG Yu-lin1,ZENG Min-de2,LU Lun-gen2,FAN Zhu-ping2,MAO Yi-min2 (1.Department of Gastroenterology,The First Affiliated Hospital of Anhui Medical University,Hefei 230032;2.Renji Hospital,School of Medicine,Shanghai Jiaotong University Shanghai Institute of Digestive Disease,Shanghai 200001);Preventive and therapeutic effects of Lycium barbarum polysaccharide on rat nonalcoholic fatty liver induced by high fat feeding[J];Anhui Medical and Pharmaceutical Journal;2007-03
2 MENG Wei - xing;YU Yong - hong Medical College of Hubei Institute for Nationalities, Enshi 445000,China;Inhibitory Effect of Artemisia Capillaris Thunb、Radix paeonia Rabrae、Spargrnium Buch - Ham and Epimedium Brevicornum Maxim on the LDL - C Oxidation[J];Journal of Hubei Institute For Nationalities Medical Edition;2004-02
3 YANG Sheng1,DONG Jun-jie2,JIANG Zhen-ling2,CHEN Qin2,FU Xu-ping1,LI Yao1,GU Shao-hua1(1.State Key Laboratory of Genetic Engineering Institute of Genetics,School of Life Sciences,Fudan University,Shanghai 200433,China;2.United Gene Company,Shanghai 200437,China);Effect of Lycium barbarum Polysaccharide on the Gene Expression Profile of Dgalactose Subacute Aging Mice[J];Journal of Fudan University(Natural Science);2008-05
4 ZHEN Yanjun,LIU Hong,WANG Lin.Department of Basic Subjects Teaching,Hebei Medical University,Hebei,Shijiazhuang 050091;Protective effect of Equisetum decoction on aorta endothelium in rats with experimental hyperlipemia[J];Hebei Medical Journal;2007-08
5 DU Yi Feng, SUN Seng Gang ,TONG E Tang Depantment of Neurology, The Affiliated Hospital of Qingdao Medical college;The study on effects of oxidatively modified low density lipoprotein on the Expression of VCAM-1 In vascular endothelial[J];Journal of Brain and Nervous Diseases;2001-02
6 CHEN Qiong,MAO Na (Longhua Hospital Attached to Shanghai University of TCM,Shanghai 200032,China);Effect of Rougan Xiezhi Recipe on Preventing the Lipidosis of Aorta in Fatty Liver of Rats[J];Journal of Liaoning University of Traditional Chinese Medicine;2007-05
7 HOU Qing-ning,HE Lan-jie.(Ningxia Medical University,Yinchuan 750004,China);Effect of Lycium Barbarum Polysaccharides on Blood Glucose,Blood Lipid and TNF-α in Type 2 Diabetic Rats[J];Ningxia Medical Journal;2009-03
8 Zheng YongfeiDepartment of Pharmacy,Zhengzhou University(Zhengzhou 450001);Health function and application of active polysaccharide[J];Cereal & Food Industry;2009-04
9 LI Ya-juan1 Murad Ferid1,2 BIAN Ka1,2,3 1. Murad Research Center for Modernized Chinese Medicine, Shanghai University of TCM 2. Department of Integrative Biology and Pharmacology, Institute of Molecular Medicine, University of Texas Medical School 3. E-Institute of Shanghai Universities, Division of Nitric Oxide and Inflammatory Medicine;Effect of Herbs for Nourishing Yin and Clearing Heat on Vascular Homeostasis[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2007-05
10 TAN Hua-bing~*,KUANG Ying-wen.~*People′s Hospital of Yunyang Medical College,Hubei 442000,China;Interfering effect of Gynostemma pentaphillia on atherosclerosis caused by high cholesterol diet in rabbits[J];Shanxi Medical Journal;2006-10
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Wo xingde; Gao Chenxian;Hong xingqiu et al(Institution of Molecular Medicine, Zhejiang College of TCM, Hangzhou 310009);Experimental Study about the Extracts of Turmerol in Dietary Rabbit with Hyperlipemia[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1999-01
2 Gao Bo, Fan Chunlei, Bao Ruimei Zhejiang College of Traditional Chinese Medicine,Hangzhou(310053);Study on Effect of Curcumin on the Expression of Mouse Macrophage LDl Receptor[J];Journal of Zhejiang College of Tcm;2005-01
3 LI Xiang-Hua1,ZHOU Liang2,HE Xiao-zhi3,TANG Xiang-bin4,PENG Yu1(1.P.E.Department,Hunan Institute of Science and Technology, Yueyang 414006,Hunan,China;2.Graduate School,Beijing Sport University,Beijing 100084,China;3.Changsha University of Science and Technology,Changsha 410071,Hunan China;4.Physical Education Department,Hunan Normal University,Changsha 410081,Hunan China);The Effects of Gynostemmapentaphyllum on Experimental Hyperglycemia Rats' Plasma Lipoprotein Metabolism and Their Related Enzyme Activity[J];Journal of Beijing Sport University;2007-02
4 SUI Da yuan *, HAN Cong cheng,YU Xiao feng,QU Shao chun (Department of Pharmacology, School of Pharmacy, Jilin University, Changchun 130021, China);Effects of Acanthopanax senticosus saponins on blood lipid metabolism and antioxidative activity in experimental hyperlipidemia rats[J];Journal of Jilin University of (Medicine Edition);2004-01
5 ZHAO Yan-wei 1,2 , YU Xiao-feng 1, XU Hua-li 1,QU Shao-chun 1, SUI Da-yuan 1 (1. Department of Pharmacology, School of Pharmacy, Jilin University, Changchun 130021, China; 2. Department of Pharmacology, Tianjin Medical College of Chinese People′s Armed Police Force, Tianjin 300162,China);Effects of IGFS on blood lipid metabolism in experimental hyperlipidemia rats[J];Journal of Jilin University of (Medicine Edition);2005-03
6 He Jiaqing Huang Xunduan ( College of Life Sciences, Anhui University);Effects of Compound Konjac Glucomannan on Hyperlipidemia in Rats[J];China Journal of Traditional Chinese Medicine and Pharmacy;2005-11
7 TANG Shi-ying,HU Gui-cai,LI Ke-ji,et al (Department of Preventive Medicine,Chengde Medical College,Hebei Chengde 067000,China);APPLICATION RESEARCH OF HYPERLIPIDEMIC ANIMAL MODEL OF GOLDEN HAMSTER[J];Journal of Chengde Medical College;2002-03
8 LI Chuan-xun,ZHOU Qin,GAO Guang-you, et al (Department of Pharmacology,Dalian Medical University,Dalian 116027,China);Effects of Ginkgoliloba leave flavonoids on blood lipid level in high lipid rats[J];Journal of Dalian Medical University;2001-03
9 JIA Yi, LI Xiao-hui (Department of Pharmacology, College of Medicine, Third Military Medical Univrersity, Chongqing 400038, China);Role of inflammation in and effects of saponin of Panax Notoginseng on formation of foam cells[J];Acta Academiae Medicinae Militaris Tertiae;2005-10
10 HUANG Dan, SHI Yuan-gang (Department of Food and Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China);Interventional effects of hawthorn, konjac and their compound on the levels of lipid and NO in plasma of rats being induced to hyperlipidemia[J];Acta Academiae Medicinae Militaris Tertiae;2005-13
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 CAO Feng-pu1,DING Cheng-hua1,XING Wen-ru1,LIU Shan-shan1,Shi Jie2(1.School of Chemistry and Pharmaceutical Engineering,Nanyang Normal University,Nanyang 473061,China;2.Department of Chemistry,Zhengzhou University,Zhengzhou,450052,China);Determination of trace bismuth and arsenic in gynostemma pentaphyllum by hydride generation atomic fluorescence spectrometry[J];Journal of Nanyang Normal University;2009-03
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 LI Rui Feng, WEN Hai Tao, LI Li, CHEN Rong, REN Dong Mei, GUO Cheng Ha o, YAN Xiao Mei, and HU Wei Cheng (Department of Pathophysiology, School of Medicine, Shandong University, Jinan 2 50012, China);Effects of Different Element from Scute Llaria Barbata on Metabolism of Endothel in and Endothelial Nitric Oxide Synthase in Arterial Endothelium[J];Chinese Journal of Arteriosc Lerosis;2002-01
2 Tang Ya-Hui Li Chi-Fen Laboratory of Hematoloyy, the Navy General Hospital, Beijing (100037);The effects of defibrase on platelet function, fibrinolytic activity and theology in rabbits on high cholesterol diet[J];Chinese Journal of Pathophysiology;1997-02
3 ZHAO Shuiping,ZHANG Xiangyu, GAO Mei,et al. Department of Cardiology, Second Affiliated Hospital, Hunan Medical University, Changsha 410011, China;Preliminary observation on the effect of the different dosage simvastatin on the endothelial function in patients with acute myocardial infarction[J];Chinese Journal of Cardiology;2001-03
4 TAN Hua-bing, CHE Zhou, CHE Jin-zhang, et al. Fangxian People' s Hospital, Hubei 442100, China;Experimental Study of Wild Gynostemma Pentaphyllum Prescription to Prevent High Sticking Syndrome[J];Journal of Chinese Microcirculation;2002-06
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