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《Journal of Third Military Medical University》 2012-10
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Effect of environmental noise on growth and neuropsychological development of newborn rats

Zheng Yanyan,Meng Meng,Zhao Congmin(Department of Pediatrics,Xinqiao Hospital,Third Military Medical University,Chongqing,400037,China)  
Objective To investigate the effect of environmental noise on the growth and neuropsychological development of newborn rats.Methods Sixteen P7 SD rats were randomly divided into a high noise group and a control group(n=8).The mean noise intensities of the high noise group and the control group were 90db(A) and 50db(A),respectively.The body length and weight of the rats were measured at P10,P15 and P20.The Morris water maze test was applied to observe the learning and memory functions of the rats,ELISA was applied for the detection of growth hormone,and RT-PCR and Western blotting were applied to observe the expression of synaptophysin(SYP) at P20.Results The body length and weight of the rats in the high noise group were lower than those in the control group [body length(cm): P10(9.54±0.1) vs(9.98±0.1),P15(10.24±0.1) vs(10.79±0.1) and P20(10.59±0.1) vs(11.68±0.1);body weight(g): P10(14.33±0.02) vs(14.51±0.02),P15(15.31±0.02) vs(15.68±0.02) and P20(16.63±0.02) vs(16.76±0.02),P0.05].Compared with the control group,the rats of the high noise group showed decreased learning ability,lower level of growth hormone and lower levels of mRNA and protein expressions of SYP [growth hormone(pg/ml):(299.7±4.9) vs(504.9±13.14),SYP mRNA:(0.182±0.008) vs(1.056±0.011),and SYP:(0.168±0.007) vs(0.432±0.025),P0.05].Conclusion Slow body length and weight growth and declined learning and memory abilities were observed in newborn SD rats under high noise environment.
【CateGory Index】: R722.1
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Chinese Journal Full-text Database 10 Hits
1 Jia Huijuan1 Li Yuan1 Wu Juanjuan1 Zhang Anmin2(1.School of Phydical Education,Shanxi University,Taiyuan Shanxi 030006;2.School of Physical Education,Shanxi University of Finance and Economics,Taiyuan Shanxi 030006);Exercise and the Hippocampal cAMP Research[J];Sport Forum;2010-01
2 YUAN Guo hong,GAO Wei juan,MENG Fan xing,et al (Department of Pathophysiology,Chengde Medical College,Hebei Chengde,067000,China);EFFECT OF YISHENJIANGZHUO DECOCTION ON INTRACEREBRAL ACHE ACTIVITY OF ISCHEMIA REPERFUSION RAT[J];Journal of Chengde Medical College;2001-02
3 GAO Jie, WU Yamin. State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China;Research progress on traumatic memory in posttraumatic stress disorder[J];Chinese Journal of Neuromedicine;2005-01
4 YU Ruo-gu,LI Gang,ZHONG Xiao-yun,et al.(Chongqing Maternal and Child Health Institute,Chongqing 400013,China);Study of effect of enriched environmental inteference on neurons in hippocampus of HIBD neonatal rats[J];Chongqing Medicine;2009-22
5 LU Cheng-Qiu, ZHONG Le, TIAN Ying, YAN Chong-Huai, SHEN Xiao-Ming. Shanghai Key Laboratory of Children's Environmental Health,Shanghai Institute for Pediatric Research,Shanghai Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China;Effects of preweaning enrichment on activity-regulated cytoskeletal protein expression and long-term memory in rats[J];Chinese Journal of Contemporary Pediatrics;2008-02
6 LI Rui1,LIU Hong-liang1,SUI Jian-feng2,FAN Zheng-li2,HUANG Lu-shuai2,WAN Zi-bing3,ZHAO Hong-mei3(1Department of Rehabilitation and Physical Therapy,Southwest Hospital;2Department of Physiology,3Experimental Center of Experimental Teaching,College of Basic Medical Sciences,Third Military Medical University,Chongqing 400038,China);Establishment of classical eyeblink conditioned reflex model in conscious and unfixed guinea pigs and study of related acquisition rule[J];Acta Academiae Medicinae Militaris Tertiae;2009-05
7 TANG Wei1,PENG Kang2,YANG Zhen-hui2,DIAO Jian-xin2,ZHU Chuan-wu1,LEI Xiao-lin3 1Medical College of Jishou University,Jishou 416000,China;2College of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,China;3Orient Pharmaceutical Limited Company,Guangzhou 510515,China;Molecular mechanism of Wulongdan for improving the learning and memory abilities of rats with chronic cerebral ischemia[J];Journal of Southern Medical University;2010-10
8 Lü Pei-yuan~1,YIN Yu~1,MA Hong-jun~2,WANG Wei-bin~1,LIANG Cui-ping~1,LI Wen-bin~(3*)(1 Department of Neurology,Hebei Provincial People's Hospital,Shijiazhuang Hebei 050051;2 Electron Microscopy Center,Hebei Medical University,3 Department of Pathophysiology,Shijiazhuang Hebei 050017,China);Ultrastructural pathologic features of neuron of hippocampus in the mice with vascular dementia[J];Journal of Chinese Electron Microscopy Society;2004-05
9 QIU Li-ru, WANG Hong-wei. (Department of Pediatrics,Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology,Wuhan,Hubei 430030, China);Effects of environment and training on learning and memory and morphological structure of hippocampus in neonatal rats[J];Chinese Journal of Child Health Care;2006-03
10 LU Cheng-qiu,ZHONG Le,YAN Chong-huai,TIAN Ying,SHEN Xiao-ming.(Shanghai Institute for Pediatric Research,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai Key Laboratory of Children's Environmental Health,Shanghai 200092,China);Effects of preweaning enriched environment on spatial memory and morphological changes of hippocampal CA1 neurons of the rats[J];Chinese Journal of Child Health Care;2008-04
China Proceedings of conference Full-text Database 3 Hits
1 ZHANG Ri-hui LIU Yu HAN Zhong-yuan (Department of Sports Physiology and Biochemistry,Shenyang Sport University,Shenyang 110102);Influence of Fatigue by Training on Memory and Hippocampus Glutamate in the Rat[A];[C];2007
2 LI Hao,YAO Ming-jiang~*,XU Li,LIU Jian-gang,ZHAO Wen-ming (Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091 China);Effects of Huannao Yicong Decoction on Cognitive Function and Expression of Bcl-2 and Bax Protein of Hippocampus in Cognitive Impairment Rats[A];[C];2009
3 ;The difficulty judgment of Chinese-English source material for interpreting[A];[C];2011
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 XU Zhi-qiang,ZHANG Tao,ZHANG Meng,et al.(Department of Neurology,Daping Hospital,Third Military Medical University,Chongqing 400042,China);Effects of proBDNF on spatial learning and memory ability in aged mice[J];Chongqing Medicine;2008-07
2 GUO Hong-mei,CHEN Qiu-xia,CAI Li-feng,PENG Yan-hua (Dept.of Biology,Guangdong Education Institute,Guangzhou,Guangdong,510303, P.R.China);The Effect of Long-term Partial Sleep Deprivation on Immune Function,Learning and Memory in Mice[J];Journal of Guangdong Education Institute;2005-05
3 JIANG Fan, WU Shenghu, YAN Chonghuai, et al Department of Pediatric Development and Behavior, Shanghai Children's Medical Center 200127;The Effect of Long-term Partial Sleep Deprivation on Learning and Memory in Young Mice[J];Chinese Mental Health Journal;2003-09
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