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《JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY》 2000-07
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Partial sequence variation of TTV in several regions of China

JI Xin-Ying 1, FU En-Qing 1, ZHOU Yu-Sen 2, WANG Hai-Tao 2, YANG Wei-Song 1 1Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China, 2Institute of Microbiology and Epidemiology, Chine  
AIM To determine the variation of sequence of TTV. METHODS We selected 6 patients with TTV-PCR-positive hepatitis from Beijing, Shenzhen, Nanjing and Shandong and isolated the TTV DNA from sera. The compared sequences were located in the ORF-1 region of TTV DNA, with a length of 309 bp. The sequence variation was known by aligning the 6 sequences and that of Japan. RESULTS It was found that there was 91% of homology between the 6 Chinese ones and all the Chinese sequences were 98% analogous to those of Japanese isolate. CONCLUSION The genotype of all the chosen Chinese ORF-1 sequences of TTV is the same as that of Japanese.
【CateGory Index】: R446.6
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1 Geng Lixia,Wang Yongfu,Guo Cunlin,Wu Rentana (The nedicine of first assistant hospital of Baotou Medical college, Baotou 014010,China);The Prevalence,Genotype of TTV in 50 Patients with Chronic Liver Disease Ofunknown Etiology[J];Journal of Baotou Medical College;2000-04
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