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《Journal of The Fourth Military Medical University》 2003-09
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Application of leucine aminopeptidse in the diagnosis of hepatic diseases

WANG Bo Liang 1, ZHONG Yue Xia 1, GU Bing Quan 2, CAO Yi Zhan 1, LU Jiang 1, TIAN Xiao Xi 1 1Department of Emergency, 2Department of Clinical Laboratories, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China  
AIM: To study changes and clinical significance of serum leucine aminopeptidse (LAP) activity in patients with hepatic diseases. METHODS: The kinetic method was employed to examine the LAP activity in the serum of 63 patients with hepatic diseases and 25 normal controls. RESULTS: The serum LAP activity increased significantly in all of the patients with liver diseases, and the LAP activity in hepatic carcinoma group was higher than those in other hepatic disease groups and normal control group ( P 0.01). CONCLUSION: LAP activity is high in patients of liver disease, especially in patients with hepatic carcinoma. It can be used as one of indexes in the diagnosis of liver cancer.
【CateGory Index】: R446.1
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