Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of The Fourth Military Medical University》 2005-18
Add to Favorite Get Latest Update

Effects of total glucosides of paeony on active Heymann nephritis in rats

SHI Peng Department of Nephrology, PLA 451 Hospital, Xi'an 710054, China  
AIM: To study the effects of total glucosides of paeony (TGP) on active Heymann nephritis (AHN) in rats. METHODS: The rat models of AHN were induced by intra-peritoneal administration of kidney homogenate and Freund's adjuvant. AHN rats were divided into 3 groups: AHN model group, TGP group and dexamethasone group. The control group was only given normal saline solution. Serum urea nitrogen, creatinine, total protein and 24-hour urinary protein were observed. RESULTS: In TGP group, the serum urea nitrogen, creatinine and 24-hour urinary protein significantly decreased (P0.01 or P0.05) while the serum total protein significantly increased, compared with those in model group. But no significant difference in renal cell histological pathology was observed between TGP- or dexamethasone-treatment group and model group. CONCLUSION: TGP is effective in the treatment of hypernitrogenemia, proteinuria and hypoproteinemia in AHN rats.
【CateGory Index】: R285;
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 3 Hits
1 ZHOU Qiang,LI Zhan guo (Department of Rheumatology and Immunology, People's Hospital, Peking University, Beijing 100044, China);Pharmaceutical effects of total glucosides of peony and its application in autoimmune disease[J];Chinese Journal of New Drugs and Clinical Remedies;2003-11
2 WANG Xing-Wang, CHEN Ming-Zhu. XU Shu -Yun (Institute of Clinical Pharmacology . Anhui Medical Unirersity . Hefei 230032);The effects of total glucosides of paeony (TGP) on T lymphocyte subsets[J];Chinese Pharmacological Bulletin;1992-05
3 WANG Bin, CHEN Min Zhu, XU Shu Yun (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032);Regulatory mechanism of total glucosides of paeony on tumor necrosis factor production by peritoneal macrophages in rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1997-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Li Xiaomei,Li Xiangpei,Wang Guosheng,et alDepartment of Rheumatology,Anhui Provincial Hospital,Hefei 230001;Effectiveness and safety of total glucosides of peony in the treatment of patients with Sjogren syndrome[J];;2006-05
2 SHAO Fu-rong,WEI Wei,LIU Hao,SUN Wu-yi,LI Xiang(Institute of Clinical Pharmacology of Anhui Medical University, Anhui Hefei 230032,China);Comparison of Protective Effect of Shaoqiduogan Extracted by Different Methods on Immunological Liver Injury in Mice[J];Journal of Anhui Traditional Chinese Medical College;2007-05
3 Anhui Technical Teachers College Fengyang 233100) LIU Han\|zhen 1\ LIU Ai\|rong 1\ LI Xiao\|liang 1\ LI yi\|song 2\;2 Anhui angriculture college Hefei 230031\;;The Chemical Composition and Pharmacodynamics Resersh Recent Development about Peeled Root of Herbaceous Penoy[J];Journal of Anhui Agrotechnical;2001-04
4 Wang Yuwei,Wang Yongjun Zhejiang Chinese Medical University Hangzhou(310053);Pharmacological Study and Clinical Application of Total Glucosides of Peony in Autoimmune Diseases[J];Journal of Zhejiang University of Traditional Chinese Medicine;2007-02
5 WANG Yuzhu;CAI Meishun;YU Zhongyuan;GAO Hubin;TIAN Song;Ll Xin(Department of Nephrology People,s Hospita1,Beijing Medical University l00044);TRANSPORT DYNAMIC STATE OF TETRAMETHYLPYRAZINE INSIDE RENAL TISSUE AFTER RENAL CAPSULE INJECT1ON IN RATS[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1996-04
6 HU Xiu-fang1, ZHANG Gao-liang2, YANG Xian-qiang3 (1. College of Life Science, Zhejiang University; 2. Yi Heng Science-Technology Development Cor LTD; 3. Department of Tea Science, Zhejiang University, Hangzhou 310029, China);Effect and Mechanism of Tea Polyphenols on Nephropathy[J];Journal of Tea Science;2002-02
7 YANG Yu-xiao,WANG Yi-xia,ZHANG Quan-qing,YANG Hong-liang,LI Fa-bing (Department of Ultrasound,the 86th Clinical Branch of PLA,Dangtu 243100,Anhui,China);Evaluation on absolute alcohol irrigation for interventional treatment effects of 502 patients with renal cyst[J];Military Medical Journal of Southeast China;2008-04
8 ;Blood purification in the treatment of acute renal failure caused by beetoxin: a report of 37 cases[J];Acta Academiae Medicinae Militaris Tertiae;2004-09
9 ZHANG Mao-qing,MA Meng(Tai'an Hospital of Women and Children's Care, Shandong Tai'an 271000, China);Clinical application and improvement of the total glucosides of peony[J];Journal of Pediatric Pharmacy;2006-01
10 SHU Qiang~* LI Xing-fu LI Dong HOU Huai-shui DAI Guo-feng LIU Hua-xiang. ~*Department of Rheumatology,Qilu Hospital of Shandong University,ji'nan 250012,China;Effect of total glucosides of paeony on the proliferation of fibroblast-like synovial cells in osteoarthritis[J];Chinese Journal of Rheumatology;2007-08
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 WANG Shi-hong~(1,2),WEI Wei~(1),XU Du-juan~(1),XU Shu-ping~(1),CUI Ying~(2)(1.Institute of Clinical Pharmacology,Anhui Medical University;Anhui Key Laboratory of Antiinflammatory and Immunopharmacology;Anhui Provincial Key Laboratory of R&D of Chinese Medicine,Hefei 230032;2.He'nan College of TCM,Zhengzhou 450008);Proliferation inhibition of TGP on SMMC-7721 Cell in vitro[J];Anhui Medical and Pharmaceutical Journal;2006-01
2 CHEN Xiang qing,WANG qin mao,FANG Hua wu,SU Cui mei (Dept. Of Pharmacy, Anhui Provincial Hospital,Anhui Hefei 230001,China);PROTECTIVE EFFECTS OF TOTAL GLUCOSIDES OF PAEONY AND EXTRACT FROM ANGELICA SINENSIS ON EXPERIMENTAL HEPATITIS[J];Journal of Anhui Traditional Chinese Medical College;2002-03
3 Anhui Technical Teachers College Fengyang 233100) LIU Han\|zhen 1\ LIU Ai\|rong 1\ LI Xiao\|liang 1\ LI yi\|song 2\;2 Anhui angriculture college Hefei 230031\;;The Chemical Composition and Pharmacodynamics Resersh Recent Development about Peeled Root of Herbaceous Penoy[J];Journal of Anhui Agrotechnical;2001-04
4 Fang Jianqiao,Kan Fangju Zhejiang College of TCM,Hangzhou(310053);Influences of Electroacupuncture on Pain Threshold and Antiˉcollagen Antibody,ILˉ1βin CIA Rats[J];Journal of Zhejiang College of Tcm;2003-01
5 WANG Xiao-ming~1,LI Fu-biao~2,LU Wen-wei~3,CHEN Xia~(3)(1.Department of Cardiology,First Hospital,Jilin University,Changchun 130021,China;2.Department of Urology,First Hospital,Jilin University,Changchun 130021,China;3.Department of Pharmacology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China);Protective effects of total glycosides of Pacony on acute myocardial ischemia in dogs[J];Journal of Jilin University(Medicine Edition);2006-03
6 CHEN Xiang-qing,WANG Qin-mao,FANG Hua-wu,et al (Dept.Of Pharmacy,Anhui Provinical Hospital,Anhui Hefei 230001,China);PROTECTIVE EFFECTS OF TOTAL GLUCOSIDES OF PAEONY AND EXTCACT FROM ANGELICA SINENSIS ON EXPERIMENTAL IMMUNOLOGICAL LIVER INJURY[J];Journal of Chengde Medical College;2004-01
7 LI Lian,WU Xiong-fei,YU Rong-jie,et al.(Department of Nephrology,Southwest Hospital,Third Military Medical University Chongqing 400038,China);A summary of renal pathological entities from 1096 cases of renal biopsy[J];Chongqing Medicine;2006-18
8 WANG Xiao-Li 1, JIANG Xue-Tao 1, LIU Gao-Lin 2, QIAN Fang 2, GUO Shou-Cheng 3 (1. Department of Pharmaceutics, College of Pharmacy, Second Military Medical University, Shanghai 200433, China; 2. Department of Pharmacy, Changzheng Hospital; 3. Confid;Comparison of drug incorporation into non-ionic micellar and O/W microemulsion systems[J];Academic Journal of Second Military Medical University;2002-01
9 YE Hai-ying 1 , ZHANG Zhong-yi 1 , GAO Shen 2 , LU Ying 2 , WANG Yan 11 Department of Pharmacy, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China; 2 Department of Pharmaceutics, College of Pharmacy, Second Military Medical University, Shanghai 200433, China;Preparation of famotidine microemulsion and its quality evaluation[J];Journal of First Military Medical University;2003-01
10 CHU Ai wu 1* ,CUI Yue hong 2,LIU Wen bo 3,JIANG Shao jun 3 (1 Department of Pharmacy,the Affiliated Hospital of Binzhou Medical College;2 Hospital of Binzhou Industrial School; 3 Electron Microscopy Laboratory,Binzhou Medical College,Shandon;Mechanism of oleic acid-induced percutaneous penetration enhancement: an ultrastructural study[J];Journal of Chinese Electron Microscopy Society;2002-02
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Gao Benbo; Dai Liming; Xu Shuyun(Institute of Natural Drugs 261042);THE SCAVENGING ACTIVITIES OF TGM AND TGP ON FREE RADICALS[J];JOURNAL OF WEIFANG MEDICAL COLLEGE;1996-01
2 Liang Junshan, Chen Minzhu and Xu Shuyun ( Clinic Pharmacoloy Institute, Anhui Medical University, Hefei);EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON CHEMILUMINESCENCE OF PERITONEAL MACROPHAGES IN RATS[J];Chinese Pharmacological Bulletin;1988-04
3 Wei Wei, Liang Junshan Zhou Aaiwu et al (The clinical Pharmacology Institute, Anhui Medical University, Hefei );EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON INTER-LEUKI'N 2 PRODUCTION[J];Chinese Pharmacological Bulletin;1989-03
4 Liang Junshan, Wei Wei & Zhou Aiwu (The Institute of Clinic Pharmacology, Anhui Mecical University, Hefei 230032);METHOD FOR MEASURING IL-1 AND EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ( TGP ) ON IL-1 PRODUCTION[J];Chinese Pharmacological Bulletin;1989-06
5 Wang Xingwang1, Wei Wei, Chen Mingzhu, Xu Shuyun ( Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032 );MECHANISM OF IMMUNOMODULATORY ACTIONS OF TOTAL GLUCOSIDES OF PAEONY IN MICE[J];Chinese Pharmacological Bulletin;1990-06
6 Li Jun, Zhao Weizhong1, Chen Minzhu , Xu Shuyun (Dept. of Phas., Institute of Clinical Pharmacology1, Anhui Medical University, Hefei 230032);EFFECT OF TOTAL GLUCOSIDES OF PAEONY ON LEUKOTRIENE B_4 BY PERITONEAL MACROPHAGES IN RATS[J];Chinese Pharmacological Bulletin;1992-01
7 WANG Xing-Wang, CHEN Ming-Zhu. XU Shu -Yun (Institute of Clinical Pharmacology . Anhui Medical Unirersity . Hefei 230032);The effects of total glucosides of paeony (TGP) on T lymphocyte subsets[J];Chinese Pharmacological Bulletin;1992-05
8 DAI Li-Ming, CHEN Xue-Guang, XU Shu-Yun (Dept Of Pharmacology, Anhui Medical University, Hefei, 230032);Protective effects of total glucosides of paeony on experimental hepatitis[J];Chinese Pharmacological Bulletin;1993-06
9 WANG Zhi-Jian; CHEN Ming-Zhu; SUN Gut-Hua; XU Shu-Yun(Anhui Medical University, Hefei 230032);Effect of total glucoside of paeony on rheumatoid arthris patients[J];CHINESE PHARMACOLOGICAL BULLETIN;1994-02
10 LI Jun; CHEN Min-Zhu; XU Shu-Yun (Inst,of Clinical Pharmacology,Anhui Medical University,hefei 230032);Effect of total glucosides of paeony on prostaglandin E_2 derived from peritoneal macrophapes and its sectional mechanism in rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1994-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved