Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of the Fourth Military Medical University》 2007-04
Add to Favorite Get Latest Update

Effect of infection on secondary necrosis of soft tissue blast injury in pigs

LI Jin-Qing, LI Xue-Yong, CHEN Shao-Zong, LI Wang-Zhou, LI Yue-JunDepartment of Plastics and Burns, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China  
AIM: To observe the influence of infection on the secondary necrosis of soft tissue blast injury in pigs. METHODS: Twenty-four blast wounds,created by explosion of a specific type of electric detonators which were fixed at 1 cm over the skin of the shoulders and hips of 6 small white domestic pigs (15-20) kg, were divided into 2 groups: group A which was treated with conventional dressing change, and group B which was not treaed until the 3rd day after injury. Tissue specimens, collected from the wounds on day 3, 6, and 9 after injury, were weighed and underwent bacteria counting. Meanwhile, the wound areas and depths were measured on the corresponding time points after injury. RESULTS: Six hours after injury, the mean area and depth of all wounds were (7.34±0.99) cm2 and (0.85±0.126) cm, without statistical significance between group A and B in both wound area and depth (P0.05). Three days after injury, the bacteria load, area, and depth of the wounds in group A were (0.157±0.171)×105 colory-forming unit/g (cfu/g), (9.17±0.60) cm2, and (1.43±0.13) cm, while those in group B were (323.417±30.631)×105 cfu/g, (10.81±0.32) cm2, and (1.66±0.09) cm, respectively, showing significant statistical differences between group A and B in the three definite measurements of wounds (P0.01). Wound areas of group B on day 6 and 9 after injury were (13.33±0.46) and (11.38±0.39) cm2, both being significantly different from those of group B on day 3 after injury (P0.01). Wound depths of group B on day 6 and 9 after injury were (2.42±0.22) and (2.46±0.25) cm, both of which had significant statistical differences as compared with those of group B on day 3 after injury (P0.01). CONCLUSION: Infection aggravates the secondary necrosis of soft tissue blast injury, and under the treatment of conventional dressing change, infection can cause about 1 cm tissue in the wound and the about 0.5 cm skin around the wound to necrosis.
【CateGory Index】: R64
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 LI Wang Zhou, LI Jin Qing, CHEN Shao Zong, LI Xue Yong Department of Plastics surgery and Burns, Tangdu Hospital, Fourth Military Medical University, Xian 710038, China;Study on vacuum-assisted closure accelerated granulation tissue formation in pig's infected soft tissue blast injury[J];Journal of The Fourth Military Medical University;2004-10
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LI Yang, SONG Liang-Wen, PENG Rui-Yun, WANG De-Wen, JIN Mei-Hong, GAO Ya-Bing, MA Jun-Jie Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing, 100850, P. R. China;Effects of SB203580 and WP631 on Smad Signal Transduction Pathway in Lung Fibroblasts after Irradiation[J];Chinese Journal of Cancer;2008-07
2 WANG Linbo,HUANG Yanlong,ZU Ling,et al.Department of Ophthalmodogy,the Tenth People's Hospital of Zhengzhou,Zhengzhou 450052,China;A Comparative Study of the Effect of Electromagnetic Pulse on Eyes of Monkey,Dog and Rabbit[J];Journal of Bethune Military Medical College;2006-03
3 LI Jin-qing,CHEN Shao-zong,LI Xue-yong,et al. (Department of Plastics and Burns,Tangdu Hospital,FMMU,Xi′an 710038,China);Vacuum-assisted closure alleviate secondary tissue necrosis of pig′s infected soft tissue blast injury[J];Chongqing Medical Journal;2005-05
4 LI Yang SONG Liangwen WANG Dewen PENG Ruiyun CUI Xuemei GAO Yabin JIN Meihong MA Junjie (Radiation Medicine Institute of Academy of Military Medicine Science, Beijing 100850);Studies on the expression of Smad3, Smad4 and Smad7 in rats with radiation pulmonary fibrosis[J];Journal of Radiation Research and Radiation Processing;2004-03
5 XIA Hongjie~(1,2) WANG Dewen~2 1 (Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China) 2 (Department of Integrated Traditional Chinese Medicine and Western Medicine for Rehabilitation,General Hospital of Chinese Peoples Armed Police Force,Beijing 100039,China);Effects of electromagnetic radiation on organism[J];Journal of Radiation Research and Radiation Processing;2008-05
6 CAI Guang, WANG De-weng , LI Quan-yue, et al. The 303 rd Hospital, PIA , Nanning Guangxi 530021, China;Effects of Mcrowave of Radar on People's Health[J];Military Medical Journal of South China;2005-02
7 Jiang tao, Wang dewen, Zhang Jian et al . Institute of Radiation Medicine, Academy of Military Medical Sciences,Beijing 100850, China;Study on the injury effect of EMP on Rhesus monkey eye[J];Medical Journal of Chinese People's Liberation Army;2004-09
8 Wang Dewen. Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, ChinaLiu Yao. The Second Institute, Ministry of Public Security, Beijing 100038, China;Terror attack and strategy of emergency medical support[J];Medical Journal of Chinese People's Liberation Army;2005-01
9 Zhou Hong, Liu Jiping, Cheng Xiaopeng et al. The Institute of Forensic Science, Beijing 100038, China;Explosive terror attack and emergency medical support[J];Medical Journal of Chinese People's Liberation Army;2005-01
10 Huang Changlin, Xue Gang, Hou Wengen. Institute of Military Training Related Medical Science of PLA, 150 Hospital of PLA, Luoyang 471031, China;Morphological mensuration of bone moulding reconstruction accelerated by “cyclic intensive training” and the influence of intervention in human beings[J];Medical Journal of Chinese People's Liberation Army;2006-04
China Proceedings of conference Full-text Database 1 Hits
1 Zhang Li Wangjin Guo Guo-Zhen Department of Radiation Medicine,Faculty of preventive Medicine,The Fourth Military Medical University.Xian 710032,China;Effects of EMP exposure on the memory function of rat pups[A];[C];2007
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 XU Long Shun,CHEN Shao Zong, QIAO Cheng, LI Xue Yong Department of Plastics, Tangdu Hospital, Fourth Military Medical University,Xi'an 710038,China;Effects of negative pressure on wound blood flow[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;2000-08
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved