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《Journal of the Fourth Military Medical University》 2007-05
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Preventive and therapeutical effect of the kernel of zanthoxylum seed oil on experimental hyperlipidemia in rats

LIU Yong-Ying1,2, WANG Duo-Ning3, LIU Yuan-Sheng1,YANG Ying3,ZHAO Yan-Wu4,WANG Zeng-Lu5, YANG Ji-Qing11Department of Physics, School of Biomedical Engineering, Fourth Military Medical University, Xi'an 710033, China, 2Xi'an Yanliang 630 Hospital, Xi'an 710089, China, 3Scientific Research Center, Xi'an Medical College, Xi'an 710068, China, 4Economical Department, Engineering College of Armed Police Force, Xi'an 710086, China, 5Center for Biotechnology, Fourth Military Medical University, Xi'an 710033, China  
AIM: To investigate the effect of the kernel of zanthoxylum seed oil (KZSO) on experimental hyperlipidemia in rats and to probe into the mechanism of preventive and therapeutical effect of KZSO. METHODS: Thirty healthy SD rats were randomly divided into 3 groups, including control group, hyperlipidemia model group and KZSO group. Control group was fed ordinary forage; model group was fed high-lipid forage; KZSO group was administrated intragastrically KZSO besides high-lipid forage. Blood samples were obtained by cutting necks after 10-week feeding. The levels of blood lipids and the hemorheological parameters were determined, and the activities of superoxide dismutase (SOD) and catalase (CAT), the content of malondialdehyde (MDA) and the restraining ability to hydroxyl free radical (RAHFR) in the liver tissues were measured. RESULTS: Compared with the model group, cholesterol, triglyceride, high blood viscosity,and low blood viscosity of the KZSO group were decreased (P0.05, P0.01), high-density lipoprotein cholesterol was increased (P0.05). The activities of SOD and CAT and the RAHFR in the liver tissues of KZSO group were increased (P0.05, P0.01) and the content of MDA was decreased (P0.05) as compared with the model group. CONCLUSION: KZSO can modulate the blood lipid, improve the indexes in hemorheology and prevent lipid hyperoxidation. The mechanism may be related to its componential effects.
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 10 Hits
1 Feng Tao~1,Zhou Xing~1,Zhou Xiaohua~1 and Wang Dong~2 (1.College of Chemistry and Chemical Engineering,Chongqing University, Chongqing 400044,China;2.Chongqing Solid Wastes Managements Center, Chongqing 400015,China);SYNTHESIS AND ANTIOXIDATION PERFORMANCE OF HYDROXYPROLINE LAURYL ALCOHOL ESTER[J];Speciality Petrochemicals;2010-01
2 Liu Yuanyuan,Cao Wei,Zhang Ya,Wang Siwang△ Institute of Materia Medica,School of Pharmacy,Fourth Military Medical University,Xi′an 710032,China;Advances in Chemical Composition and Biological Activity of Zanthoxy lum L*[J];Chinese Journal of Ethnomedicine and Ethnopharmacy;2012-03
3 TIAN Feng 1, QI Xiao-xu 2, ZHENG Zhen-hui 1 (1. Department of Laboratory Animal Sciences, Peking University Health Center, Beijing 10083, China; 2. Crown Bioscience Co.Ltd);Effects of Polyunsaturated Fatty Acids on Hematology and Main Organs of Rats[J];Sichuan Journal of Zoology;2008-06
4 LIU Jie1,2 XU Ming-sheng2 WAN Xi-mei2 JIANG Yan2 LIU Jian-tao3 ZHAO Li3(1.Jiangsu Food Science College, Huaian, Jiangsu 223001, China;2. College of Food Science and Engineering, Jiangxi Agriculture University, Nanchang,Jiangxi 330045, China;3.School of Life Science, Jiangxi Normal University of Science and Technology, Nanchang,Jiangxi 330013, China);Effect of egg yolk oil on blood lipids in mouse[J];Food & Machinery;2008-01
5 XIAO Hui-min,HE Yue,WANG Si-wang,WANG Jian-bo,XIE Yan-hua,YUAN Juan-li,HE Zhong-min(Institute of Materia,SchoolofPharmacy,Fourth Military Medical University,Xi'an 710032 China);Component Analysis of Semen Oil of Zanthoxylum Bungeanum Maxim and Its Effect on Hyperlipidemic Rabbits' Model[J];Progress in Modern Biomedicine;2011-08
6 XIAO Hui-min,HE Yue,WANG Si-wang ,XIE Yan-hua,HE Zhong-min(Institute of Materia,School of Pharmacy,Fourth Military Medical University,Xi'an,Shaanxi,710032 China);Effects of Xin'an Soft Capsule's on Adiposis Hepatica Rats' Model[J];Progress in Modern Biomedicine;2012-30
7 LV Bin1,2,MA Jian-zhong1,2,GAO Dang-ge1,2,GAO Jian-jing1,2,HUO Yong-qiang1(1.College of Resource and Environment,Shaanxi University of Science & Technology,Xi’an 710021,China;2.Key Laboratory of Ministry of Education on Chemical Science and Technology of Light Chemical Additives,Shaanxi University of Science & Technology,Xi’an 710021,China);Research Advance of Prickly Ash Seed Oil and its Application Prospect in Leather Industry[J];Leather Science and Engineering;2013-03
8 DU Lijun1,2,ZHENG Guohua1,NIU Xianqian3 1 College of Horticulture,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China 2 Institute of Natural Products of Horticultural Plants,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China 3 Fujian Institute of Tropical Crops,Zhangzhou,Fujian 363001,China;Research Progress in Biological Activities of Zanthoxylum L.[J];Chinese Journal of Tropical Crops;2013-05
9 BIAN Feng-xia1,ZHENG Xu-xu1,2,YIN Zhong-yi2,ZHANG Yu-jing1(1.School of Environmental and Biological Engineering,Chongqing Technology and Business University,Chongqing 400067,China;2.Research Center of Medical Chemistry and Chemical Biology,Chongqing Technology and Business University,Chongqing 400067,China);Optimization of Alkaline Removal of Oil from Sichuan Pepper (Zanthoxylum bungeanum) Pericarp before Oil Pressing and Oxidative Stability of Sichuan Pepper Oil[J];Food Science;2013-16
10 YIN Cai-na2, SHI Yong-hui 1, 2, WANG Yan-yan2 , WANG Shu-ping2, LE Guo-wei1, 2 (1 The State Key Laboratory of Food Science and Technology,Jiangnan University, Jiangsu, Wuxi 214122; 2Jiangnan University, School of Food Science and Technology, The Institution of Food Nutrition and Safety,Jiangsu,Wuxi 214122);Effects of Lard and Tea Seed Oil or Oxidized Tea Seed Oil on the Antioxidation Capability and Blood Lipid Metabolism of Mice[J];Acta Nutrimenta Sinica;2008-06
【Citations】
Chinese Journal Full-text Database 4 Hits
1 WANG Duo Ning 1, ZHAO Yan Wu2, TIAN FuRong3 1Department of Basic Medicine, Shaanxi Medical College, Xi'an 710068, China, 2Department of Chemistry, Faculty of Preclinical Medicine, 3Department of Radiomedicine, Faculty of Preventive Medicine,;Protein quantification with coomassie bulliant blue microplate-colormetric[J];Journal of The Fourth Military Medical University;2001-06
2 Heng Liang, Li Chen, Jia Min et al.Department of Pharmacology, Fourth Military Medical University, Xi'an 710032, China;Therapeutic effect of pericarpium zanthoxylum oil on experimental hyperlipemia in mice[J];Medical Journal of Chinese People's Liberation Army;2005-11
3 CHEN Zhi-qiang 1*,DING Qi-feng1,YIN Zhi-wei1,ZHANG Xiu-jun1,HUANG Huai-peng2,LI Hong-xia1(1.Institute of Integration of TCM-WM Hebei Medical University,Shijiazhuang 050017,China;2.Shinwey Pharmaceutical Co.Ltd,Shijiazhuang 051430,China);Effects of Zhikeping on the Expression of Aortic ICAM-1 in a Rat Model of Experimental Early Atherosclerosis[J];Natural Product Research and Development;2006-03
4 MA Chuan guo, BI Yan lan,LIN Min gang, LI Xiao yang (School of Grain, Oil and Food, Zhengzhou Institute of Technology, Zhengzhou 450052, China);ANALYSIS OF CHEMICAL COMPONENTS IN HUSK AND KERNEL OIL OF ZATHOXYLUM BUNGEANUM SEED[J];Journal of Zhengzhou Grain College;2002-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 XU Wen,HAI Chun-xu ,YANG Chen,LIU Rui (Department of Toxicology,The Fourth Military Medical University,Xi'an710032,Shaanxi,China);The Study of Free Radical Toxicity and Genotoxicity of CHP on Male Mice[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-02
2 YANG Xue-kang,HAI Chun-xu,LIANG Xin,ZHAO Hai-long,BAI Hua.(Department of Toxicology,the Fourth Military Medical University,Xi'an 710033,China);Establishment of an Acute Aging Model in Mice Induced by γ-ray Irradiation[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-06
3 LIANG Xin,LI Wen-Li,HAI Chun-xu,YANG Xue-kang,ZHANG Wei,BAI Hua.(Department of Toxicology,the Fourth Military Medical University,Xi'an 710033,Shanxi,China);Oxidative damage which caused by γ-rays promotes aging[J];Carcinogenesis,Teratogenesis & Mutagenesis;2010-05
4 LUAN Ji-mei, HU Ming-jin, ZHANG Xiao-dong (Chemical College of Qingdao University, Qingdao 266071, China);The Study on Protein Determination through the Spectrophotometric Analysis by Means of Dyes[J];Journal of Anhui Institute of Education;2004-03
5 Li Jing(Huangshan institute of forestry science,Huangshan 245000,China);Radical scavenging activity and Constituents analysis of methanol extracts from leaves of Malus hupehensis[J];Anhui Agricultural Science Bulletin;2009-05
6 Jing HongYu (Nanyou Chuangyi landscaping Co.Ltd.,Shenzhen 518054,China);Radical Scavenging Activity and Constituents Analysis of Methanol Extracts from Flower of Viburnum Macrocephalum[J];Anhui Agricultural Science Bulletin;2009-21
7 WEI Yan-ming et al (College of Animal Science and Technology,Northwest Agriculture and Forestry University,Yangling,Shaanxi 712100);Protective Effects of Extract of Maize Plumule on Myocardial Ischemia Induced by Pituitrin in Rabbits[J];Journal of Anhui Agricultural Sciences;2007-07
8 YAO Qian et al(College of Food Science,Shanghai Fisheries University,Shanghai 200090);Antioxidant Activity of Carboxymethyl Chitosan with Different Substituted Degrees[J];Journal of Anhui Agricultural Sciences;2008-16
9 ZHU Shan-liang et al(Jiangsu Institute of Education,Nanjing,Jiangsu 210013);Effects of Lactobacillus Rich in Selenium on Tissue Lipid Peroxidation Response in Mice[J];Journal of Anhui Agricultural Sciences;2008-20
10 DENG Hong-mei et al(College of Chemistry and Life Science,Maoming University,Maoming,Guangdong 525000);Effect of Anionic Surfactant SDS on Some Physiological Indexes of Tomato Seedling[J];Journal of Anhui Agricultural Sciences;2008-35
China Proceedings of conference Full-text Database 10 Hits
1 ;Studing for the interference of AS on apoptosis of cardiac myocytes in ischemic and reperfused rats[A];[C];2005
2 HE Xiao Hui,CHEN Wen,CHEN Jian ZHang,et al The Jiang Xi Traditional Chinese Medicine Profession Training College,Fuzhou(344000);The Experiemntal Study of Shuang Pu Powder Treating Chronic Atrophic Gastritis model Rats[A];[C];2008
3 ZHANG Yu~1 Song cui-yan~1 Liu hai-tao~2 Sun Wei-nan~1 (1 Inner Mongolia Agricultural University,2 Fisheries Research Institute of Inner Mongolia);Dalinuoer Lake and Ganggeng Lake Valsalva Jarraud study of antioxidant enzyme[A];[C];2011
4 JIANG Yan (College of Life Science and Technology,Xinjiang University,Urumqi 830046,China);Effects of the anthocyanins from Xinjiang black mulberry fruit on anti-aging[A];[C];2011
5 LI Juan,ZHOU Yuan-da,HE Hai-xia,WAN Xia (Departement of clinical Pharmacology of Pharmacy,the First Affiliated Hospital of Chongqing Medical University,CHONGQING 400016,China);Comparison of the distribution and pharmacokineties of levofloxacin in aqueous humor and vitreous following oral or intravenous administration[A];[C];2011
6 WAN Xia,ZHOU Yuan-da (Departement of clinical Pharmacology,the First Affiliated Hospital,Chongqing Medical University,CHONGQING 400016,China);Pharmacokineties of levofloxacin of tears and corneal tissues in the rabbits eyes following oral and intravenous administration[A];[C];2011
7 ;The experimental study on the toxicity of Shandougen to SD Rats[A];[C];2009
8 CAO Hua-bin,Guo Xiao-quan*,LEI Peng,LI Hao-tang,ZHANG Cai-ying,GUO Xin,TIAN Shan (College of Animal Science and Technology,Jiangxi Agriculture University,Nanchang 330045,China);Effects of High Dietary Calcium from Different Sources on Free Radical Metabolism of Serum and Renal Mitochondria of Growers[A];[C];2011
9 Ni Ming,Yuan Hui (Veterinary Medicine of Hunan Agricultural University,HUNAU,Changsha 410128);Effects of gossypol induced luteal cells apoptosis in Mice[A];[C];2011
10 Su Yinhai Xu Shan Wu Zhenlie (Wenzhou Medical & Pharmacologic Science Institute,Wenzhou 325003);PHARMACOLOGIC ACTION OF PAECILOMYCES TENUIPES[A];[C];1996
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Liang Lixin et al. Department of Toxicology, Second Military Medical University Shanghai, 200433;STUDIES ON THE GENOTOXICITY AND INHIBITORY EFFECT ON GAP JUNCTION INTERCELLULAR COMMUNICATION OF BILE ACID[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1998-02
2 La mingping Chen meihua;Proceeding of Pharmacological Research on silymarin[J];Anhui Agricultural Science Bulletin;2007-07
3 LIU Chang-jian et al (College of Life Science,Dalian Nationalities University,Dalian,Liaoning 116600);Progress in Health Benefit and Therapeutic Effects of Probiotics[J];Journal of Anhui Agricultural Sciences;2009-20
4 LIU Jing et al (Department of life science, Shaanxi Institute of Education , Xi′an, Shaanxi 710061);Study on the Reducing Blood Lipid and Antioxidition Effects of Flavonoids from Eucommia ulmiodes Olirer Leaves[J];Journal of Anhui Agricultural Sciences;2010-11
5 HAN Shuang et al (Guizhou Provincial Key Laboratory of Mountainous Environment,Guiyang,Guizhou 550001);Gas Chromatograph Determination of Methyl-n-nonyl-ketone Content in Dried Houttuynia cordata Thunb[J];Journal of Anhui Agricultural Sciences;2010-28
6 LI Pin-ai et al(Luohe Medicinal College,Luohe,Henan 462002);Study on the Effect of PERICARPIUM ZANTHOXYLI Extracts on Proliferation and Apoptosis of SGC-7901 Cell[J];Journal of Anhui Agricultural Sciences;2011-20
7 LI Juan-juan et al (College of Agronomy of Inner Mongolia Agricultural University,Hohhot,Inner Mongolia 010018);Reviews on Influence Factors of Peppermint Oil Composition and Content[J];Journal of Anhui Agricultural Sciences;2011-36
8 Shi-Xiong Jiang, Xi-Shan Wang, Chang-Hui Geng and Gui-Yu Wang Department of Colorectal Surgery, Tumor Hospital, Harbin Medical University, Harbin, Heilongjiang, 150040, P. R. China;Altering trend of clinical characteristics of colorectal cancer: a report of 3607 cases[J];Chinese Journal of Cancer;2009-01
9 HOU Dangshe1,2,CHEN Shuanhu1(1.Dept.Chem., Northwest Univ., Xi'an 710069, Shaanxi, China;2.Qianxian Teachers School, Qianxian 713300, Shaanxi, China);Esterification deacidification of Chinese prickly ash seed oil[J];Journal of Baoji College of Arts and Science(Natural Science Edition);2003-01
10 XIE Jian-chun,SUN Bao-guo,SHA Shuang,ZHENG Fu-ping,DANG Wan-bin(College of Chemical and Environmental Engineering,Beijing Technology and Business University,Beijing 100037,China);STUDY ON SYNTHESIS OF FOOD FLAVOR 4-PENTENOIC ACID[J];Journal of Beijing Technology and Business University(Natural Science Edition);2007-01
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 LIN Jia-bin et al(Changchun University of Chinese Medicine,Changchun,Jilin 130117);GC-MS Identification of Volatile Oil from Zanthoxylum schinifolium[J];Journal of Anhui Agricultural Sciences;2012-30
2 HOU Jie,WANG Bao-wei(Institute of High Quality Waterfowl,Qingdao Agricultural University,Qingdao 266109,China);Current Situation and Development Prospect of Goose Fatty Liver Industry in China[J];Packaging and Food Machinery;2012-06
3 ZHANG Yanjun1,YANG Tuxi2*,WEI Anzhi2,FENG Shijing2(1 College of Life Science,Northwest A&F University,Yangling,Shaanxi 712100,China;2 College of Forestry,Northwest A&F University,Yangling,Shaanxi 712100,China);Accumulation Patterns of Total Flavonoids,Total Polyphenol during Growth of Zanthoxylum bungeanum Maxim.and Its Antioxidant Activities[J];Acta Botanica Boreali-Occidentalia Sinica;2013-03
4 WANG Lu1,LIU Li-juan2,YAN Jian-ye1,LI Shun-xiang1(1.Key Lab of Modernization of Chinese Medicine,School of Pharmacy,TCM University of Hunan,Changsha,Hunan 410208,China; 2.School of Pharmacy,TCM University of Hunan,,Changsha,Hunan 410208,China);Research progress on pharmacological actions and extraction technology of yolk oil[J];Journal of Traditional Chinese Medicine University of Hunan;2012-03
5 CAO Wei,WANG Si-wang,YANG Qian,HAO Rong-rong,LI Ying,CUN Li(Department of natural medicine,School of Pharmacy,the Fourth Military Medical University,Xi'an 710032,P.R.China);Study on the Identification and Content Determination of α-linolenic Acid in the Send oil from Zanthoxylum bungeanum Maxim[J];Science Technology and Engineering;2012-03
6 NIU Xiao-na;School of Chemical Engineering,Shaanxi University of Technology;;Research Progress on Extraction Process of Pepper Seed Oil[J];Jiangsu Condiment and Subsidiary Food;2013-04
7 WANG Chao-kai CHEN Zhen-lin GAN Quan etal;Processing technique of hanged leaf fat[J];Meat Industry;2010-03
8 WU Yin-ming LI Pei-hong YANG Lin ZENG Pan(Sichuan Academy of Plant Project,Zizhong 641200,China);Investigation on Zanthoxylum germplasm and Establishment of its Resource Repository in Sichuan[J];Journal of Sichuan Forestry Science and Technology;2011-06
9 YIN Ling,ZHANG Xiao-ming,LI Li,ZHAO Xiu-mei(Institute of Medical Information,Chinese PLA General Hospital,Beijing 100853,China);Effect of Tea-seed Oil on Serum Lipid Level and Atherosclerosis Formation in Rabbits[J];Food Science;2011-07
10 ZHU Rui-xue1,ZENG Wei-cai1,ZHAO Zhi-feng1,GAO Hong1,YAN Zhi-nong2(1.College of Light Industry,Textile and Food Engineering,Sichuan University,Chengdu 610065,China; 2.Sichuan Green Food Development Center,Chengdu 610041,China);Chemical Components and Antibacterial Activity of Hanyuan Zanthoxylum bungeanum Seed Oil[J];Food Science;2011-17
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Zhou Jie,Ding Jianping,Wang Zenong,Xie Xiaofeng (Anhui Agricultural University,Hefei 230036);Effect of Tea polysaccharides on Blood glucose,Blood lipid and Immunological Function of Mice[J];JOURNAL OF TEA SCIENCE;1997-01
2 ZHOU Rui-Hai, GAO Hai-Qing(Affiliated Hospital of Shandong Medical University, Jinan, 250012);ADVANCES OF DRUG THERAPY FOR HYPERLIPIDEMIA[J];THE CHINESE JOURNAL OF CLINICAL PHARMACOLOGY;1999-01
3 Zhang Rong; Liu Yu; Liu Bingwen(Apoiipoprotein Research Unit, School of Basic Medical Sciences(Chengdu 610041);The Colorimetric Method for Measuring Activities of Lipoprotein Lipase and Hepatic Lipase in Plasma[J];JOURNAL OF WEST CHINA UNIVERSITY OF MEDICAL SCIENCES;1996-01
4 Guo Minliang;Jiang Yongming(Basic Science Division; Jiangsu Agricultural college;Yangzhou 225009;China).;^Effect of Ingredients of Coomassie Brilliant Blue Color-developing Reagent on Protein Assay.[J];PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS;1996-06
5 JIANG XIANCHENG, ZHUANG QINQI, MEI MEIZHEN(Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Shanghai First Medical College, Shanghai);A SIMPLE METHOD FOR THE DETERMINATION OF LECITHIN CHOLESTEROL ACYLTRANSFERASE[J];;1985-02
6 Wu Manping, Huang Ruxin, Wei Ying, Li Yongwu, Chen Peifang,Zhuang Qingqi, Mei Meizhen (Deparment of Biochemistry, School of Pharmacy, Shanghai Medical University, Shanghai);A STUDY ON THE METABOLIC FUNCTION OF RAT HEPATIC ENDOTHELIAL LIPASE[J];;1989-05
7 Kong Qingsheng, Wang Yanying, Jiang Ying Department of Biochemistry, Jining Medical College (Jining 272013);Studies on Extraction and Hypolipidemic Activity of Polysaccharides from Pumpkin[J];CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS;2000-03
8 Zuo Shaoyuan, Qian Jinfu, Wan Shunkang, Di Yong, Zhou Jinghua Department of Biochemistry, DaLi Medical College (Dali 671000);Research of Polysaccharide from Spirulina platensis on Hypoglycemic and Hypolipidemic Effect in Experimental Diabetic Rats[J];Chinese Journal of Biochemical Pharmaceutics;2000-06
9 Zhou Hui-Ping; Jiang Xun-Tian; Wang Shu-Ru; Chen QiOng-Hua(Division of Biochemistry, China Pharmaceutical University, Manjing 210009);Effect of Polysaccharide from Enteromorpha prolifera on Lipemia,SOD Activity and LPO Content[J];;1995-02
10 Wang Dongfeng,Xie Xiaofeng ( Anhui Agricultural University, Hefei 230036) Wang Yin long ( Anhui Medical University, Hefei 230036);STUDYING PROGRESS IN TEA POLYSACCHARIDES AND ITS PHARMACOLOGY[J];Natural Product Research and Development;1996-01
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