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《Journal of Datong Madical College》 2004-02
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The Effect of Intracenelro-ventricular Injection of PUERARIN on Arterial Blood Pressure and Heart rate in Rats

Luo Chao Cheng Desen Peng Jixia et al (Combined Medical Functional Laboratory,Yungyang Medical College.Hubei shiyan 442000)  
Objective:To study the effect and mechanism of Intracenelro-ventricular Injection of PUERARIN on the reduction of arterial bood pressure(BP)and heart rate(HR) in rats.Methods:BP and HR acted as the index,to observe the effect of PUERARIN.injected on the artificially ventilaled SD rats,anesthsized with urethate and immobilized by gallamine triethiodide,with 60 minutes continual observation of changes of the curres of BP and HR.Then the result was compared with that of the contral group and NS group.Results:After injection of PUERARIN.The rats BP and HR dropped significantly,with the minimum level of BP and HR between 5 to 15 minutes. Compared with the control group and the NS group,BP and HR have marked difference (p0.01).Conclusion:Intracenelro-ventricular Injection of PUERARIN has a significant effect on the reduction of rats BP and HR..
【CateGory Index】: R285
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