Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Zoological Research》 2002-03
Add to Favorite Get Latest Update

Toxicity of Penicillic Acid in Broiler Chickens

HE Zu ping 1,YUAN Hui 2,3 ,FENG Mei fu 1,4 (1 State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, the Chinese Academy of Sciences, Beijing 100080, China; 2 College of Animal Science and Technology, Huna  
In order to provide scientific grounds for the prevention and treatment of penicillic acid poisoning on the poultry and the mechanism of penicillic acid toxicosis, the toxicity of penicillic acid has been investigated in broiler chickens. By the artificial contamination, we observed the pathological manifestation and measured the changes of blood biochemical value,the residue of penicillic acid in tissue and organs of the broiler chickens within 60 days. The results showed that: ① major pathological changes was fatty and vacuolar degeneration of hepatocytes, cloudy swelling of renal epithelial cells and myocardial cells; ② the contents of MCV and MCHC in poisoned groups were less than that in control group, whereas the activities of SGPT, LDH and AKP in the formers were higher than those in the latter; ③ as for the distribution of penicillic acid, the amount was the highest in liver, and the residue in kidney outweighed that in heart. It was understandable that there was a relation between the residue of penicillic acid and the degree of lesion. The target organ of penicillic acid poisoning was liver.
【Fund】: 湖南省自然科学基金资助项目 (970 3 7)
【CateGory Index】: S859.8
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 3 Hits
1 GUO Le,YAN Hui-yun,YUAN Hui(College of Veterinary Medicine, Hunan Agricultural University,Changsha,Hunan,410128,China);Advance in Toxicity of Penicillic Acid[J];Progress in Veterinary Medicine;2008-03
2 GUO Le,YUAN Hui*(College of Veterinary Medicine,HNAU,Changsha 410128,China);Renal injury and its mechanism on mice induced by penicillic acid from Penicillium cyclopium[J];Journal of Hunan Agricultural University(Natural Sciences);2010-03
3 WANG Di1J,IA Jin-sheng2(1.Shenyang Institute of Monster Medicine Animal Feed Control,Shenyang Liaoning110031;2.Shenyang Entry-Exit In-spection and Quarantine Bureau,Shenyang Liaoning 110016);Progress in Studies on Penicillic Acid[J];Jilin Animal Husbandry and Veterinary Medicine;2010-12
【Citations】
Chinese Journal Full-text Database 1 Hits
1 HE Zu ping,YUAN Hui(College of Animal Science and Technology,HNAU,Changsha 410128,PRC);Detoxification of Penicillic Acid by Chemical Treatments[J];JOURNAL OF HUNAN AGRICULTURAL UNIVERSITY;2000-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Ying,FENG Mei yun,WEN Ru (Teaching and Research Section of Exercise Biochemistry, BUPE, Beijing 100084, China);Mechanism and Monitoring of Sports Anemia[J];Journal of Beijing University of Physical Education;2001-03
2 Luo Yanfen,Guan Dehua,Wang Lixia (Beijing Children's Hospital,Capital University of Medical Sciences,Beijing 100045);The study of serum myocardial enzymogram in 187 children patients with infective diarrhea[J];Beijing Medical Journal;2001-05
3 LIANG Da-gang1, TU Zhen-li1, LU Shun-lin, XU Rong-qing2(1.Dept. of Special Animal Science, Zhejiang University, Zhejiang Hangzhou 310029,China; 2.The Country Government of Yutou, Zhejiang Jiangshan 324100, China);Effect of γ-Glutamyl Transpeptidase Activities in the Hemolymph of the Fluoride Poisoned Silkworm Larvae:[J];Bulletin of Sericulture;2004-02
4 LIANG Da-gang, LU Shun-lin,LU Huayun ,NI Chunxiao (Hangzhou Agriculture Bureau, Hangzhou 310002, China;College of Animal Science, Zhejiang University, Hangzhou 310029, China);Effect of γ-Glutamyl Transpeptidase Activities in the Hemolymph of the Fluoride Poisoned Silkworm Larvae[J];Bulletin of Sericulture;2005-04
5 Li Junye,Fang Guizhen,Li Hongzhen,Jin Zhongling(Key Laboratory of Bio-based Material Science and Technology,Ministry of Education(Northeast Forestry University),Harbin 150040,P.R.China);Liu Jianwei(the Train Center of Decoration and Fitment of Shanghai Guild);Synthesis of Ether with Cellulose and Picric Acid and Its Adsorption to Creatinine[J];Journal of Northeast Forestry University;2009-04
6 ZHOU Li-guo.Departement of Surgery,Zhuzhou Municipal First Hospital,Zhuzhou,412000,China;The Significance of Detection for Helicobacter Pylori Infection in Perioperative Period Patients with Liver Cirrhosis[J];Journal of Chinese Physician;2001-06
7 Dai Jianghong, Wu Jiyao, Liu Kaitai, et al (Department of Preventive Medicine, Xinjiang Medical College,Urumqi 830054);Experimental Study on the Effects of Arsenic-Fluorine on Serum Sulfhydryl,Blood Pyruvic Acid and Urine Hydroxyproline[J];ENDEMIC DISEASES BULLETIN (CHINA);1998-02
8 SU Xue Jia 1, ZHANG Hui Ying 2, YI Ding Hua 3, ZHANG Zhi Yong 1, ZHU Bin 1 1Department of Thoracic Surgery, PLA No.88 Hospital, Taian 271000, China, 2Clinic of First Rest home, Taian dispartment of Shandong Province Military Command, Taian 271000, China, 3Department of Cardiovascular Surgery, Xijing Hospital, Xian 710033, China;Effects of perfusion solution temperature on its protection against immature canine lung injury during cardiopulmonary bypass[J];Journal of The Fourth Military Medical University;2004-08
9 KUANG Wei~1 GUO Yu-hua~1 YIN Zhao-hua~1 ZHAO Guo-qi~(1*) WANG Jia-qi~2 LI Shu-cong~2(1.College of Animal Science and Technology,Yangzhou University,Yangzhou 225009,China;2.Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100094,China);Effects of Different Levels of VA on the Ruminal Environmental Parameters in Holstein Cows in Vitro[J];Chinese Journal of Animal Nutrition;2006-03
10 LIU Huan qi 1,HUO Hui jun 1,LU Zhan jun 1,SHAO Chun lan 2, GONG Qing jun 2,GUAN Wei feng 3,WANG Lin an 1,WANG Hong bin 1 (1 Northeast Agricultural University,Harbin 150030,China;2 Laiyang Agricultural College,Laiyang,shangdong, 265200,China );Study on the Influence of QFM Mixture on Kidney Function of Dogs at Anaesthetic Dose[J];Progress In Veterinary Medicine;2002-06
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CHEN Jian-shan et al (Environment and Plant Protection College,SCUTA,Danzhou,Hainan 571737);Application of ITS Sequences in Fungi Classification and Identification[J];Journal of Anhui Agricultural Sciences;2007-13
2 ZHANG Ke-Feng ZHANG Zi-Ping ** CHEN Yun LIN Peng WANG Yi-Lei* (The Key Laboratory of Science and Technology for Aquaculture and Food Safety,Fisheries College, Jimei University,Xiamen 361021,China );Antioxidant Defense System in Animals[J];Chinese Journal of Zoology;2007-02
3 WANG Ying,REN Li-song,LI YAN-dong,et al;Preparation,purification and identification of specialties of monoclonal antibody against chloramphenicol[J];Journal of Jilin University(Medicine Edition);2008-02
4 QUAN Zhu fu, YANG Chong, LI Ning, LI Jie shou (Research Institute of General Surgery,Nanjing General Hospital of Nanjing Command,Nanjing 210002,Jiangsu,China);Change in early postoperative intestinal permeability and its relation with systemic inflammatory response[J];Parenteral & Enteral Nutrition;2002-02
5 SHI Gang 1 reviewing, CHEN Jia yong 2, XU Peng yuan 2 checking (1.Department of General Surgery,North Sichuan Medical College, Nanchong 637007,Sichuan,China; 2.Department of Surgery,The Second Affiliated Hospital of Kunming Medical College,Kunming 650031,Yunnan,China);The injury and the protection of intestinal mucosal barrier[J];Parenteral & Enteral Nutrition;2004-01
6 BI Xian-min,LIANG Zhi-qing,SHI Li-feng(Department of Gynaecology and Obstetrics,Southwest Hospital,Third Military Medical University,Chongqing 400038,China);Determination of functional affinity of rhEndoglin conjugated eptide[J];Acta Academiae Medicinae Militaris Tertiae;2007-08
7 YUAN Hui,YI Hou-sheng,WEN Li-xin,PENG Tao,BAI Hong-guo,ZHOU Qing-feng(College of Animal Science and Technology Hunan Agricultural University,Changsha 410128,China);EFFECT OF PENICILLIUM NOTATUM AND PENICILLIUM TOXIN ON AMINO ACIDS AND VITAMIN CONTENTS IN FEEDSTUFFS[J];ACTA ZOONUTRIMENTA SINICA;1999-04
8 ZHU Can-sheng,SONG Chao-jun,PENG Shuang-qing,et al(Department of Laboratory,Shaanxi Provincial Institute for Endemic Disease Control,Xi'an 710003,China);Preparation and characterization of a monoclonal antibody against T-2 toxin[J];Chinese Journal of Control of Endemic Diseases;2006-05
9 PAN Xiao-cheng~(1), QI Ke-zong~(1),SUN Guo-ren~1,ZHU Liang-qiang~(2) (1.Anhui Agricultural University, Hefei ,Anhui,230036, China; 2.Anhui Institute of Veterinary Medicine Inspection,Hefei,Anhui,230036,China);Progress on Monoclonal Antibodies of Veterinary Drug[J];Progress In Veterinary Medicine;2005-04
10 GUO Le,YAN Hui-yun,YUAN Hui(College of Veterinary Medicine, Hunan Agricultural University,Changsha,Hunan,410128,China);Advance in Toxicity of Penicillic Acid[J];Progress in Veterinary Medicine;2008-03
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 HE Xiu-yuan,ZHU Jia-zeng,CHEN Yuan,HE Cong,YANG Yu-rong,HAN Jin-jin,DENG Li-xin(College of Animal Husbandry and Veterinary Science,Henan Agricultural University,Zhengzhou,Henan,450002,China);Diagnosis of Calf Poisoning Caused by Moldy Peanut Vine[J];Progress in Veterinary Medicine;2011-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved